- Acute Myeloid Leukemia Research
- Multiple Myeloma Research and Treatments
- Drug-Induced Hepatotoxicity and Protection
- Advanced biosensing and bioanalysis techniques
- Liver Diseases and Immunity
- Health and Medical Research Impacts
- Immune cells in cancer
- SARS-CoV-2 and COVID-19 Research
- Leprosy Research and Treatment
- Berberine and alkaloids research
- Extracellular vesicles in disease
- Analytical Chemistry and Sensors
- Acute Lymphoblastic Leukemia research
- Molecular Junctions and Nanostructures
- Hepatitis Viruses Studies and Epidemiology
- Science and Science Education
- Information Science and Libraries
- Telomeres, Telomerase, and Senescence
- Hematopoietic Stem Cell Transplantation
- Education and Public Policy
Universidade do Porto
2012-2025
Hospital de São João
2011-2024
IPO Porto
2012-2024
Purpose: Many chemotherapy drugs have the potential for producing liver damage, though they occur rarely and are deemed idiosyncratic, believed to be attributable host response possible immunologic mechanism. Thalidomide is a synthetic derivative of glutamic acid used in myeloma myelodysplastic syndromes; hepatotoxicity considered very rare, with 7 cases described literature. We present case 77 year-old male unremarkable past medical history, admitted our hospital two months earlier acute...
percentage, a semi-quantitative evaluation of Glasgow Microenvironment Score 7 was performed.Also, Prognostic Score, that is widely known as systemic inflammatory-based marker, determined for each patient. 8Results: Diabetic patients presented significant higher glycaemia than the control (190.1 ± 13.6 mg/dL vs 98.2 3.6 mg/dL, p < 0.001, respectively).Decreased survival rates were observed in diabetic (611.5 916.0, = ns).Tumours exhibited increased fibrosis relatively to adjacent mucosa both...