A5077645932- Invertebrate Immune Response Mechanisms
- Bone Metabolism and Diseases
- Statistical Methods and Inference
- Financial Risk and Volatility Modeling
- Insect symbiosis and bacterial influences
- Insect Resistance and Genetics
- Genetic diversity and population structure
- Stochastic processes and financial applications
- Genomics and Phylogenetic Studies
- Studies on Chitinases and Chitosanases
- Perovskite Materials and Applications
- Silk-based biomaterials and applications
- Antimicrobial Peptides and Activities
- Trace Elements in Health
- Fungal and yeast genetics research
- Wheat and Barley Genetics and Pathology
- Lepidoptera: Biology and Taxonomy
- Advanced Measurement and Detection Methods
- Aldose Reductase and Taurine
- Signaling Pathways in Disease
- Inflammatory mediators and NSAID effects
- Phytochemical compounds biological activities
- Turfgrass Adaptation and Management
- Enzyme function and inhibition
- Berberine and alkaloids research
Yulin Normal University
2024-2025
Nanjing University of Aeronautics and Astronautics
2015-2024
Shanghai Jiao Tong University
2023
Southern Medical University
2023
Shanghai Ninth People's Hospital
2023
Jinzhou Medical University
2023
Zhujiang Hospital
2023
Anhui Agricultural University
2009-2022
The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine
2022
Sichuan University
2018
In eukaryotes, multiple genes encode histone proteins that package genomic deoxyribonucleic acid (DNA) and regulate its accessibility. Because of their positive charge, 'free' (non-chromatin associated) histones can bind non-specifically to the negatively charged DNA affect metabolism, including repair. We have investigated effect altering dosage on repair in budding yeast. An increase gene resulted enhanced damage sensitivity, whereas deletion a H3-H4 pair reduced levels free H3 H4...
Smoking is a risk factor associated with bone and oral diseases, particularly periodontitis. Nicotine, the major toxic component of tobacco, able to affect quality quantity bone. Osteoblasts serve an important role in formation. Thus far, effects nicotine on metabolism‑associated gene protein expression osteoblasts have been controversial mechanisms remain unclear. The present study assessed alterations osteogenic activity by performing Cell Counting kit‑8 assay investigate proliferation,...
Staphylococcus aureus is the aetiological agent of many hospital- and community-acquired infections. Toll-like receptor 2 (TLR2) has been shown to play a crucial role in host defence against S. infection. The aim this study investigate roles heterogeneous TLR family proteins TLR2, TLR4 RP105 during Peritoneal macrophages from mice were exposed aureus. Their production inflammatory cytokines chemokines, their expression cell-surface markers interactions between assessed presence or absence...
In this study, a complete mitochondrial genome (mitogenome) sequence of Abraxas suspecta (Lepidoptera: Geometridae) is isolated and characterized. The DNA 15,547 bp length contains 2 ribosomal RNA genes, 23 putative transfer (tRNA) genes including an extra tRNAAsn (AUU), 13 protein-coding adenine (A) + thymine (T)-rich region. nucleotide composition gene organization are identical to those other lepidopteran, except for the presence copy trnN (AUU). Of 38 twenty-five (9 PCGs 16 tRNAs)...
BmSuc1, a novel animal-type β-fructofuranosidase (β-FFase, EC 3.2.1.26) encoding gene, was cloned and identified for the first time in silkworm, Bombyx mori. BmSuc1 specifically highly expressed midgut silk gland of Until now, function unclear. In this study, it found that expression changes fifth instar were consistent with growth rate gland. Next, aid CRISPR/Cas9 system, locus genetically mutated, homozygous mutant silkworm strains truncated β-FFase (BmSUC1) proteins established. larvae...
Abstract Dose rate meters operating in pulse counting mode usually encounter the problem of uneven energy response. While current methods coating a single probe with metal layer can effectively improve flatness response, range flat response is limited. In this research, multi-probe compensation method was proposed to solve CsI(Tl) dose meter. method, different relative curves were obtained by adding hardware compensations probe. Then, two four selected and weighted obtain flatter within...
This article mainly studies the asymptotic properties of recursive kernel density estimation for high-frequency data with a long time span. Under appropriate conditions, variance, bias, mean squared error, and optimal bandwidth are obtained. The normality is proven by using moment inequalities ρ-mixing data. Numerical simulations show that provides good fitting results invariant function Vasicek diffusion process. Empirical analysis reveals not only reflects distribution characteristics...
This paper mainly focuses on the asymptotic properties of histogram density estimation for long-span high-frequency data in diffusion processes. We use some inequalities mixing as research tools to derive variance, integrated mean squared error, and globally optimal bandwidth under strong conditions. Furthermore, normality with convergence rate is provided. The simulation results show that sample size increases, fitting become better better, it less affected by sampling interval. empirical...
* 1 四川农业大学农学院, 四川雅安 625014; 2 中国农业科学院作物科学研究所国家小麦改良中心 / 国家农作物基因资源与基因改良 重大科学工程, 北京 100081; 3 江苏省农业科学院农业生物技术研究所, 江苏南京 210014; 4 CIMMYT 中国办事处, 5 中 国科学院成都生物研究所, 四川成都 610041 摘 要: 高分子量谷蛋白亚基 Bx7
The superfamily of short-chain dehydrogenases/reductases (SDRs) is crucial in biosynthetic and signalling pathways, which the carbonyl reductases (CBRs) subfamily important biosynthesis tetrahydrobiopterin (BH4). BH4 an essential coenzyme for animals, its deficiency can lead to neurological diseases. There are few reports on CBRs involved synthesis silkworms, Bombyx mori. Here, we identified 67 SDR genes B. mori (BmSDR) through whole genome survey first time. Based bioinformatics analyses...
The silk-spinning and Lepidopteran model insect Bombyx mori (Bombycidae) is a mulberry specialist. BmSuc1 gene the first β-fructofuranosidase (β-FFase) encoding identified in animals, β-FFase acts as an essential sucrase for glycometabolism modulation silkworm larvae, involved resistance to alkaloids. Glyphodes pyloalis Walker (Lepidoptera: Pyralidae) important pest leading heavy economic loss of sericulture. However, no molecular or biochemical information available about G. homologs. In...
Tetrahydrobiopterin (BH4) is a vital coenzyme for several enzymes involved in diverse enzymatic reactions animals, and BH4 deficiency can lead to metabolic neurological disorders due dysfunction its metabolism. In the silkworm natural homozygous mutant leml, key enzyme sepiapterin reductase (BmSPR) de novo synthesis pathway of inactivated, resulting severe synthesis. However, it not known why leml larvae survive second-instar stage which pathways their death when deficient. Here, we...