A5101525960- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Advanced Neuroimaging Techniques and Applications
- Voice and Speech Disorders
- EEG and Brain-Computer Interfaces
- Circadian rhythm and melatonin
- Autism Spectrum Disorder Research
- Health disparities and outcomes
- Dysphagia Assessment and Management
- Mercury impact and mitigation studies
- Head and Neck Cancer Studies
- Anesthesia and Neurotoxicity Research
- Mental Health and Psychiatry
- Advanced MRI Techniques and Applications
- Attention Deficit Hyperactivity Disorder
- Bioinformatics and Genomic Networks
- Genetic Associations and Epidemiology
- Neural and Behavioral Psychology Studies
- Statistical Methods and Bayesian Inference
- Animal Disease Management and Epidemiology
- Cystic Fibrosis Research Advances
- Anesthesia and Pain Management
- Hemispheric Asymmetry in Neuroscience
- Neurological disorders and treatments
- Nausea and vomiting management
University of North Carolina at Chapel Hill
2021-2024
Capital Medical University
2014-2024
Beijing Tian Tan Hospital
2024
Beijing Tongren Hospital
2011-2022
Ministry of Education of the People's Republic of China
2021
South China Normal University
2021
Nanjing Medical University
2016-2021
Nanjing Brain Hospital
2016-2021
University of Stirling
2018
Beijing Center for Disease Prevention and Control
2011
General anesthesia (GA) provides an invaluable experimental tool to understand the essential neural mechanisms underlying consciousness. Previous neuroimaging studies have shown functional integration and segregation of brain networks during anesthetic-induced alteration However, organization pattern hubs in remains unclear. Moreover, comparisons with well-characterized physiological unconsciousness can help us unconsciousness. Resting-state magnetic resonance imaging was performed...
Background Previous neuroimaging studies have described shared and distinct neurobiological mechanisms between autism spectrum disorders (ASDs) attention-deficit/hyperactivity disorder (ADHD). However, little is known about the similarities differences in topologically structural connectivity patterns two disorders. Methods Diffusion tensor imaging (DTI) deterministic tractography were used to construct brain white matter (WM) networks of children adolescents (age range, 6–16 years); 31 had...
Background The mechanism of general anesthesia (GA) has been explored for hundreds years, but unclear. Previous studies indicated a possible correlation between NREM sleep and GA. purpose this study is to compare them by in vivo human brain function probe the neuromechanism consciousness, so as find out clue GA mechanism. Methods 24 healthy participants were equally assigned or propofol sedation group sleeping ability. EEG Ramsay Sedation Scale applied determine stage depth respectively....
Medialization thyroplasty or injection laryngoplasty for unilateral vocal fold paralysis cannot restore mobility of the fold. Recent studies have shown that transplantation mesenchymal stem cells is effective in repair nerve injuries. This study investigated whether adipose-derived cell could recurrent laryngeal injury. Rat models injury were established by crushing with micro forceps. Adipose-derived (ADSCs; 8 × 105) differentiated Schwann-like (dADSCs; extracellular matrix injected at site...
Abstract The human cerebral cortex is a vital component of brain function, but the genetic influences on cortical functional organization remain poorly understood. In this study, we used parcellation-based approach to process resting-state and task-evoked magnetic resonance imaging (fMRI) from over 48,000 individuals in UK Biobank ABCD studies. We identified 47 loci associated with areas networks at rest, 15 which also affected connectivity during task performance. observed patterns...
Little is currently known about the longitudinal developmental patterns of hubs in whole‐brain white matter (WM) structural networks among toddlers with autism spectrum disorder (ASD). This study utilized diffusion tensor imaging (DTI) and deterministic tractography to map WM 37 ASD 27 age‐, gender‐ quotient‐matched controls delay (DD) aged 2–3 years old at baseline (Time 1) 2‐year follow‐up 2). Furthermore, graph‐theoretical methods were applied investigate alterations network these...
To investigate the role of laryngeal electromyography (LEMG) in diagnosis and treatment spasmodic dysphonia (SD).The clinical manifestations, characteristics motor unit potentials (MUPs), recruitment potentials, nerve evoked (EPs) LEMG, as well changes after botulinum toxin (BTX) treatment, were analyzed 39 patients with adductor SD.The main manifestations a strained voice phonation interruptions; addition, displayed hyper-adducted vocal folds during phonation. LEMG revealed significantly...
Abstract It is crucial to understand how anesthetics disrupt information transmission within the whole-brain network and its hub structure gain insight into network-level mechanisms underlying propofol-induced sedation. However, influence of propofol on functional integration, segregation, community networks were still unclear. We recruited 12 healthy subjects acquired resting-state magnetic resonance imaging data during 5 different effect-site concentrations (CEs): 0, 0.5, 1.0, 1.5, 2.0...
<b><i>Background:</i></b> Sevoflurane is a volatile anesthetic that widely used in pediatric anesthesia due to its low toxicity. However, whether neonatal exposure sevoflurane induces long-lasting cognitive impairment remains unclear. It has been reported neuronal injury the main cause of sevoflurane-induced learning and memory disabilities development brain. But, specific mechanism not well elucidated. The synapse occurs earlier than cell brain injury. synaptic...
摘要:
Objective To evaluate the reliability and validity of Chinese version Griffith empathy measure parent ratings(Chinese GEM-PR). Methods Eighty-five autism spectrum disorder(ASD) 344 children typical development(TD) were assessed using GEM-PR scale.The detected by exploratory factor analysis confirmatory analysis. Results The Cronbach-coefficient (Chinese version) was 0.860, split half 0.731 test-retest 0.851.A two-factor model obtained factory KMO 0.902.The revealed a good fit,...
The aim of this paper is to systematically investigate merging and ensembling methods for spatially varying coefficient mixed effects models (SVCMEM) in order carry out integrative learning neuroimaging data obtained from multiple biomedical studies. "merged" approach involves training a single model using comprehensive dataset that encompasses information all the Conversely, "ensemble" creating weighted average distinct models, each developed an individual study. We prediction accuracy...
1 华南师范大学, 国家绿色光电子国际联合研究中心, 广州 510006) ( 2 华南先进光电子 研究院, 广东省光信息材料与技术重点实验室&彩色动态电子纸显示技术研究所, 3 华南师范大学心理学院, 光与身心健康实验室, 510631) 4 华南师范大学基础教育与培训 5 肇庆华师大光电产业研究院, 智能照明与身心健康研究中心, 肇庆 526000)