Gheorghe G. Bălan

ORCID: 0000-0002-2919-4940
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About
Contact & Profiles
Research Areas
  • Gallbladder and Bile Duct Disorders
  • Gastroesophageal reflux and treatments
  • Liver Disease Diagnosis and Treatment
  • Esophageal and GI Pathology
  • Pancreatic and Hepatic Oncology Research
  • Pancreatitis Pathology and Treatment
  • Liver Disease and Transplantation
  • Pediatric Hepatobiliary Diseases and Treatments
  • Eosinophilic Esophagitis
  • Gastrointestinal disorders and treatments
  • Medical Device Sterilization and Disinfection
  • Microscopic Colitis
  • Healthcare cost, quality, practices
  • Helicobacter pylori-related gastroenterology studies
  • Diet and metabolism studies
  • COVID-19 and healthcare impacts
  • Childhood Cancer Survivors' Quality of Life
  • Extraction and Separation Processes
  • Hepatitis Viruses Studies and Epidemiology
  • Biliary and Gastrointestinal Fistulas
  • Liver Diseases and Immunity
  • Colorectal Cancer Screening and Detection
  • Bariatric Surgery and Outcomes
  • Gastric Cancer Management and Outcomes
  • Healthcare and Environmental Waste Management

Grigore T. Popa University of Medicine and Pharmacy
2016-2025

Spitalul Clinic Judeţean de Urgenţe "Sf. Spiridon" Iaşi
2015-2025

Pediatrics and Genetics
2024

Ştefan cel Mare University of Suceava
2024

Titu Maiorescu University
2024

Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș
2024

Institute of Applied Physics
2022

Academy of Sciences of Moldova
2022

Hai phong University Of Medicine and Pharmacy
2010

Spitalul Clinic de Recuperare
1995

Background: Over the last two decades, therapy for benign esophageal strictures has shifted from empirical dilatations and surgery to evidence-based complex endoscopic surgical procedures, aiming achieve long-term patency. Aim: The purpose of our study is provide descriptive evidence regarding appropriate tailored medical, endoscopic, management strictures. Methods: This retrospective includes patients with strictures; data collected encompass complete patient profiles, detailed etiologic...

10.3390/jcm14072181 article EN Journal of Clinical Medicine 2025-03-22

The Romanian Society of Gastrointestinal Endoscopy developed a multicentre, prospective study to evaluate the frequency and epidemiological features inflammatory bowel disease (IBD) in an adult population that refers gastroenterology centres Romania.Eighteen with adequate diagnostic therapeutic facilities uniformly distributed across Romania reported through proforma new old IBD cases between 1 June 2002 2003. rates incidence prevalence ulcerative colitis (UC) Crohn's (CD) have been per 100...

10.1097/00042737-200411000-00012 article EN European Journal of Gastroenterology & Hepatology 2004-10-14

The novel COVID-19 infection has spread all over the world and is still generating a lot of issues at different levels. There lack control in disease early diagnosis rapid evolution, which impacts both medical economic system. Young gastroenterologists should adapt to overcome current difficulties continue their life general training. This multi-center national study, aims assess perspective young (residents specialists) from six university centers Romania regarding training psychological...

10.3389/fpsyg.2020.579177 article EN cc-by Frontiers in Psychology 2020-12-23

Background and Objectives: The aim of this study was to investigate the association between H. pylori positivity with specific symptoms, risk factors endoscopic patterns among pediatric population in northeastern Romania. Materials Methods: A prospective performed 18 months on 185 children aged 6−18 years an indication for upper digestive endoscopy. Demographic, anamnestic, symptomatic, histologic data were recorded. Results: Of 116 pylori-positive children, most affected group 15−17 years....

10.3390/jcm11092432 article EN Journal of Clinical Medicine 2022-04-26

In response to rising concerns over multidrug resistance patterns in acute cholangitis patients, this retrospective study was conducted at the Emergency County Hospital Timisoara, Romania, encompassing patients treated between August 2020 and 2023. The aimed investigate influence of prior interventions, specifically sphincterotomy (with or without stent placement), on current clinical microbiological profiles patients. By differentiating with a history endoscopic retrograde...

10.3390/life13112205 article EN cc-by Life 2023-11-13

Background: Endoscopic retrograde cholangiopancreatography (ERCP) has been one of the most intensely studied endoscopic procedures due to its overall high complication rates when compared other digestive endoscopy procedures. The safety and outcome such have linked multiple procedure- or patient-related risk factors. aim our study is evaluate whether morphology major duodenal papilla influences ERCP outcomes rates. Methods: A total 322 patients with a native included in over an eight month...

10.3390/jcm9061637 article EN Journal of Clinical Medicine 2020-05-28

Abstract Introduction Pancreatic malignancies represent highly fatal diseases with poor prognosis and constantly increasing incidence despite modern diagnostic therapeutic options. Both endoscopic ultrasound (EUS) retrograde cholangiopancreatography (ERCP) are regarded as mainstays in pancreatic cancer management. The present study aims to evaluate whether accuracy EUS fine‐needle aspiration or biopsy (FNA FNB) diagnosis is influenced by prior biliary stenting technical anatomical features...

10.1002/jcu.23186 article EN Journal of Clinical Ultrasound 2022-03-07

Duodenoscopes have been widely used for both diagnostic and therapeutic endoscopic retrograde cholangiopancreatography (ERCP) procedures, but recently, numerous outbreaks of multidrug-resistant organisms (MDRO) infections reported which has led to extensive research their possible causes. Consequently, the aim this study is search duodenoscope surface damages that could provide an alternative plausible source infections.In order assess outer inner surfaces, a was dismantled samples were...

10.3390/molecules24122343 article EN cc-by Molecules 2019-06-25

Calcium peroxide nanoparticles (NPs) coated with sodium alginate (CaO2–Alg NPs) were synthesized and tested to obtain a disinfectant capable of fighting nosocomial infections produced by the duodenoscope investigations. was characterized X-ray diffraction, Fourier transform infrared spectroscopy, electronic microscopy, electron spin resonance, thermal analysis. CaO2–Alg NPs proved ensure moderate oxidative environment at pH = 7, as suggested analysis resonance spectra free radicals that...

10.1021/acsanm.3c04470 article EN ACS Applied Nano Materials 2023-12-12

The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) infection has required a complete change in the management of patients with gastrointestinal disease who needed to undergo endoscopic procedures. In second year pandemic, due restrictions for elective procedures large number cancer were prevented from early diagnosis several digestive cancers, which led serious burden health system nowadays needs be dealt with. We designed prospective study that...

10.20944/preprints202401.2075.v1 preprint EN 2024-01-31

Similar autonomic innervation of the esophagus and left atrium with sympathovagal imbalance seems to explain association between non-valvular atrial fibrillation (AF) gastroesophageal reflux disease (GERD). We aimed assess this via parameters heart rate variability in time (SDNN) frequency (low-frequency (LF)/high-frequency (HF) ratio) domains by 24-hour electrocardiographic (ECG) Holter monitoring.One hundred thirty-five patients were prospectively included a joint team consisting...

10.5152/tjg.2017.16540 article EN The Turkish Journal of Gastroenterology 2017-01-30

Cholangiocarcinoma is the most common malignancy of bile ducts causing intrahepatic, hilar, or distal duct obstruction. Most jaundiced patients are diagnosed with unresectable tumors in need for palliative drainage and chemotherapy. Endobiliary radiofrequency ablation (RFA) an adjuvant technique that may be applied prior to biliary stenting. The aim our study was assess efficacy endobiliary RFA stent insertion cholangiocarcinomas.Twenty-five (eight treated stenting 17 alone) were included a...

10.3390/diagnostics12081804 article EN cc-by Diagnostics 2022-07-26

Duodenal gangliocytic paragangliomas are rare neuroendocrine tumors primarily localized in the periampullary area. Though mostly asymptomatic, they can present with various symptoms, most often jaundice, anemia and abdominal pain. The paper is a case series report, describing our personal experience patients presenting to Emergency Unit different symptoms due duodenal paraganglioma. Endoscopic resection safe indicated of cases, being also associated lower medical costs. EUS plays central...

10.3390/life13030597 article EN cc-by Life 2023-02-21

New hydrogels nanocomposites, based on iminoboronate and ZnO nanoparticles (ZnO-NPs), were obtained characterised in order to develop a new class of disinfectants able fight the nosocomial infections produced by duodenoscopes investigation procedures. The formation imine linkages between chitosan aldehyde was demonstrated using NMR FTIR spectroscopy, while supramolecular architecture developed systems evaluated via wide-angle X-ray diffraction polarised optical microscopy. morphological...

10.3390/polym15122669 article EN Polymers 2023-06-13

The progression of liver fibrosis and the presence portal hypertension are two key points in follow-up severity assessment patients with chronic disease. Objective evaluation such aspects has proven to be difficult due lack reproducible standardized non-invasive methods. Therefore, aim this study was evaluate whether spleen stiffness (SS) can rule out high-risk varices (HRVs) non-alcoholic fatty disease (NAFLD). We designed a prospective cohort 48 consecutive diagnosed compensated advanced...

10.3390/app13095764 article EN cc-by Applied Sciences 2023-05-07
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