Irina Roșca

ORCID: 0000-0003-3080-1709
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About
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Research Areas
  • Electrospun Nanofibers in Biomedical Applications
  • Nanocomposite Films for Food Packaging
  • Wound Healing and Treatments
  • Silk-based biomaterials and applications
  • Hydrogels: synthesis, properties, applications
  • Advanced Drug Delivery Systems
  • Antimicrobial agents and applications
  • Nanoparticles: synthesis and applications
  • Lignin and Wood Chemistry
  • Antifungal resistance and susceptibility
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Medical Device Sterilization and Disinfection
  • Fungal Infections and Studies
  • Synthesis of Tetrazole Derivatives
  • Polymer Surface Interaction Studies
  • biodegradable polymer synthesis and properties
  • Polymer composites and self-healing
  • Advancements in Transdermal Drug Delivery
  • Fish Biology and Ecology Studies
  • Hemiptera Insect Studies
  • Insect Resistance and Genetics
  • Extraction and Separation Processes
  • Wood Treatment and Properties
  • Synthesis and properties of polymers

Romanian Academy
2018-2025

Institutul de Chimie Macromoleculară Petru Poni
2016-2024

Carol Davila University of Medicine and Pharmacy
2024

Institute of Macromolecular Chemistry
2016-2023

Grigore T. Popa University of Medicine and Pharmacy
2023

InterAcademy Partnership
2023

University of Limerick
2014-2019

Kompetenzzentrum Holz
2005

The paper reports new hydrogels based on quaternary ammonium salts of chitosan designed as biocidal products. derivative was crosslinked with salicylaldehyde via reversible imine bonds and supramolecular self-assemble to give dynamic which respond environmental stimuli. crosslinking mechanism demonstrated by 1H NMR FTIR spectroscopy, X-ray diffraction polarized light microscopy. hydrogel nature, self-healing thixotropy were proved rheological investigation visual observation, their...

10.1016/j.carbpol.2024.122389 article EN cc-by-nc Carbohydrate Polymers 2024-06-13

Introduction: Duodenoscopes have been widely used for both diagnostic and therapeutic endoscopic retrograde cholangiopancreatography procedures. Numerous outbreaks of duodenoscope-associated infections involving multidrug-resistant bacteria recently reported. Plasma activated water (PAW) has considered an effective agent surface decontamination is increasingly disinfection medical equipment. The aim this study was to evaluate whether the duodenoscopes currently on market are suited repeated...

10.2147/idr.s159243 article EN cc-by-nc Infection and Drug Resistance 2018-05-01

Different formulations containing Pluronic F127 and polysaccharides (chitosan, sodium alginate, gellan gum, κ-carrageenan) were investigated as potential injectable gels that behave free-flowing liquid with reduced viscosity at low temperatures displayed solid-like properties 37 °C. In addition, ZnO nanoparticles, lysozyme, or curcumin added for testing the antimicrobial of thermal-sensitive gels. Rheological investigations evidenced small changes in transition temperature kinetics gelation...

10.3390/polym15020355 article EN Polymers 2023-01-10

The study describes the curing and thermal behavior of a new castor oil maleic anhydride adduct/epoxy oils/5–Bromosalicylic acid coatings their composites with wood. epoxidized oils were flax hemp. kinetic parameters degradation processes calculated. resistance coated wood surfaces against Cladosporium cladosporioides, Aspergillus brasiliensis, Penicillium chrysogenum was tested. Color changes, FT–IR SEM conducted before after fungal attack. decay color change raw treated samples fungi Based...

10.1021/acsami.0c00682 article EN ACS Applied Materials & Interfaces 2020-03-05

In this study, lemon balm (Melissa officinalis L.) and dill (Anethum graveolens essential oils (EOs) were encapsulated into collagen hydrolysates extracted from bovine tendons rabbit skins, both mixed with chitosan (CS) by using the coaxial electrospinning technique for potential wound dressing applications. The morphology chemical composition of electrospun nanofibers investigated scanning electron microscopy (SEM) attenuated total reflectance Fourier transform infrared spectroscopy...

10.3390/pharmaceutics13111939 article EN cc-by Pharmaceutics 2021-11-16

Microporous chitosan nanofibers functionalized with different amounts of an antimicrobial agent via imine linkage were prepared by a three-step procedure including the electrospinning chitosan/PEO blend, PEO removal and acid condensation reaction in heterogeneous system 2-formylphenylboronic acid. The fibers' characterization was undertaken keeping mind their application to wound healing. Thus, FTIR 1H-NMR spectroscopy, it confirmed successful imination fibers conversion degree amine groups...

10.3390/pharmaceutics14010117 article EN cc-by Pharmaceutics 2022-01-04

Wound management represents a continuous challenge for health systems worldwide, considering the growing incidence of wound-related comorbidities, such as diabetes, high blood pressure, obesity, and autoimmune diseases. In this context, hydrogels are considered viable options since they mimic skin structure promote autolysis growth factor synthesis. Unfortunately, associated with several drawbacks, low mechanical strength potential toxicity byproducts released after crosslinking reactions....

10.3390/pharmaceutics15030975 article EN cc-by Pharmaceutics 2023-03-17

In this present study, we developed and characterized a series of supramolecular G4 hydrogels by integrating β-cyclodextrin (β-CD) boronic acid linkers into matrix to enhance antibacterial activity against Staphylococcus aureus (S. aureus). We systematically investigated how varying the number free moieties (ranging from two six), along with guanosine β-CD content, influences both structural integrity antimicrobial efficacy these materials. Comprehensive characterization using FTIR, circular...

10.3390/gels11010035 article EN cc-by Gels 2025-01-04

Background/Objectives: The discovery of new molecules to which bacteria have not yet developed resistance is a significant medical priority. Synthetic flavonoids are good candidates for developing antimicrobials. Our study investigates series newly synthesized tricyclic with several different substituents on the flavonoid core. Methods: By varying nature rings A and B, structure–activity relationship using microbial strains has been performed. antibacterial antifungal properties these...

10.3390/antibiotics14030307 article EN cc-by Antibiotics 2025-03-16

The paper describes new epoxy derivatives and their influences on wood thermal fungi stability. Epoxy were thermally photochemically cross-linked. softwood samples, modified with succinic anhydride, impregnated individually or in the mixture glycidyl methacrylate, diglycidyl ether of bisphenol A, epoxidized grapeseed oil cross-linked afterward. samples methacrylate first exposed to UV at 254 nm for 30 min all surfaces 5 h 130 °C 150 °C. characterized by thermogravimetric analysis decay...

10.1021/acssuschemeng.8b00331 article EN ACS Sustainable Chemistry & Engineering 2018-03-01

Cerium oxide nanoparticles present the mimetic activity of superoxide dismutase, being able to inactivate excess reactive oxygen species (ROS) correlated with a large number pathologies, such as stents restenosis and occurrence genetic mutations that can cause cancer. This study presents synthesis biological characterisation nanoconjugates based on iron interconnected cerium conjugates.The magnetite-nanoceria has been done in several stages, where key process is coating polyethyleneimine its...

10.3390/nano9111565 article EN cc-by Nanomaterials 2019-11-04
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