- Autoimmune Bullous Skin Diseases
- Cutaneous lymphoproliferative disorders research
- Nail Diseases and Treatments
- Dermatology and Skin Diseases
- Skin Diseases and Diabetes
- Psoriasis: Treatment and Pathogenesis
- Osteoarthritis Treatment and Mechanisms
- Bone fractures and treatments
- Bone Tissue Engineering Materials
- Tendon Structure and Treatment
- Drug-Induced Adverse Reactions
- Orthopedic Surgery and Rehabilitation
- Orthopedic Infections and Treatments
- Drug Solubulity and Delivery Systems
- Skin and Cellular Biology Research
- Infectious Diseases and Mycology
- Total Knee Arthroplasty Outcomes
- Autoimmune and Inflammatory Disorders
- Orthopaedic implants and arthroplasty
- Vascular Tumors and Angiosarcomas
- Aortic Thrombus and Embolism
- Beetle Biology and Toxicology Studies
- Genomic variations and chromosomal abnormalities
- Elbow and Forearm Trauma Treatment
- Wnt/β-catenin signaling in development and cancer
Grigore T. Popa University of Medicine and Pharmacy
2014-2025
Clinical Emergency Hospital Bucharest
2023-2025
Imperial College London
2012-2013
Wound management represents a continuous challenge for health systems worldwide, considering the growing incidence of wound-related comorbidities, such as diabetes, high blood pressure, obesity, and autoimmune diseases. In this context, hydrogels are considered viable options since they mimic skin structure promote autolysis growth factor synthesis. Unfortunately, associated with several drawbacks, low mechanical strength potential toxicity byproducts released after crosslinking reactions....
Introduction: Chronic osteomyelitis is a persistent infection of the bone that poses significant challenges, particularly when associated with pathological fractures and extensive defects. This case report highlights application Masquelet’s induced membrane technique (MIMT) in managing complex distal femur defect 50-year-old male long-standing history chronic osteomyelitis. The patient presented non-union fracture, severe osseous destruction, infection, requiring multidisciplinary approach....
ABSTRACT Although deterioration of silicone maxillofacial prostheses is severely accentuated in smoking patients, the phenomenon has not been systematically studied. To address a gap literature concerning stability during service, this contribution, effect cigarette smoke on aspect and physical properties M511 elastomer was evaluated. The aspect, surface, overall material, pigmented or not, were followed by AFM, color measurements, FTIR, water contact angle TGA‐DTG DSC, hardness compression...
Hyaluronic acid, in the form of a gel or viscoelastic colloidal solution, is currently used for viscosupplementation joints affected by osteoarthritis, but its effectiveness under debate relation to newer alternatives. Based on meta-analytical arguments, present article reinforces opinion that there are still no decisive arguments complete replacement, use adapted peculiarities disease manifestation and patients. A “broad” comparison first made with almost all alternatives studied last...
Although niflumic acid (NA) is one of the most used non-steroidal anti-inflammatory drugs, it suffers from poor solubility, low bioavailability, and significant adverse effects. To address these limitations, complexation NA with cyclodextrins (CDs) a promising strategy. However, complexing CDs molecular weight drugs like can lead to CE. This study explores development inclusion complexes 2-hydroxypropyl-β-cyclodextrin (2HP-β-CD), including effect converting its sodium salt (NAs) adding...
We present a diabetic patient with associated two dermatoses: dermopathy ("shin spots") and bullae. A 34-year-old man, long history of diabetes mellitus, hypertension, moderate obesity presented to Dermatology Unit for diagnosis his skin lesions. On clinical examination multiple, light brown, irregular patches, atrophic scars crusts over large bullae were observed on the anterior aspect both legs.doi: http://dx.doi.org/10.12669/pjms.315.7521How cite this:Brzezinski P, Chiriac AE, Pinteala T,...
Alopecia areata (AA) is a T-cell-mediated autoimmune disease and affects up to 2% of the population. There need for more profound rigorous understanding structure composition human hair affected by AA in order manage this disease. The aim article understand effects on hair.Several physico-chemical investigation methods, such as Scanning Electron Microscopy (SEM), Transmission (TEM), Energy-Dispersive X-ray Spectroscopy (EDX), microbeam Small Angle Scattering (SAXS), were used analyze samples...
Scanning electron microscopy (SEM) and energy dispersive X-ray (EDX) techniques have been used in various fields of medical research, including different pathologies the nails; however, no studies focused on obtaining high-resolution microscopic images elemental analysis disorders caused by synthetic nails acrylic adhesives.Damaged/injured fingernails use acrylate glue were investigated using SEM EDX methods.SEM proved that nails, glue, damaged contact with a morphology composition compared...
The yellowish discoloration of the palms and skin is reported under different terms: xanthodermia, hypercarotenemia, carotenemia, carotenodermia. Yellow may be associated with hypothyroidism, diabetes mellitus, hyperlipoproteinemia, liver disease, renal meaning that carotenemia not synonym yellow skin, but rather one cause. We presented an 8 year-old boy a soles, observed by mother 3 weeks prior to medical examination. was uniformly distributed, symmetrically, no nails changes, just mild...
The terminology Erosio blastomycetica interdigitale is used to describe a clinical entity characterized by erosions disposed interdigitalis on the hands and /or feet, in persons with poor controlled diabetes mellitus, agent incriminated being Candida Albicans.DOI: http://dx.doi.org/10.3329/bjms.v13i1.16623Bangladesh Journal of Medical Science Vol. 13 No. 01 January2014: 105-106
Cutaneous larva migrans (CLM) is common in children tropical and subtropical areas but exceptionally rare temperate zones.1 We report a case of CLM child from climate country. An 8-year-old boy was seen with facial skin eruption. The lived an industrialised city Romania, spent 2 months his summer holidays rural village, 150 km away, playing cats dogs. Initial pruritus on the left cheek followed by progressive serpiginous erythematous papules along aspect …
Hyaluronic acid, in the form of a gel or viscoelastic colloidal solution, is currently used for viscosupplementation joints affected by osteoarthritis, but its effectiveness under debate relation to newer alternatives. Based on meta-analytical arguments, present article reinforces opinion that there are still no decisive arguments complete replacement use adapted peculiarities disease manifestation and patients. A "broad" comparison first made with almost all alternatives studied last...
This study investigates novel biomaterials developed for bone regeneration, using cellulose and collagen type I matrices enhanced with hydroxyapatite or InterOss. These materials demonstrate significantly improved mechanical properties, notably in...