A5017793460- Nanoparticles: synthesis and applications
- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Phytochemicals and Antioxidant Activities
- Sesquiterpenes and Asteraceae Studies
- Pharmacological Effects of Natural Compounds
- Natural product bioactivities and synthesis
- Analytical Methods in Pharmaceuticals
- Moringa oleifera research and applications
- Phytochemistry and Bioactivity Studies
- Antibiotics Pharmacokinetics and Efficacy
- Drug Solubulity and Delivery Systems
- Malaria Research and Control
- Antibiotic Resistance in Bacteria
- Gold and Silver Nanoparticles Synthesis and Applications
- Plant biochemistry and biosynthesis
- Nanoparticle-Based Drug Delivery
- Analytical Chemistry and Chromatography
- Medicinal plant effects and applications
- Laser-Ablation Synthesis of Nanoparticles
- Medicinal Plants and Neuroprotection
- Lanthanide and Transition Metal Complexes
- Protein purification and stability
- Microencapsulation and Drying Processes
- Phytochemicals and Medicinal Plants
Grigore T. Popa University of Medicine and Pharmacy
2013-2024
Tagetes erecta L. is a popular ornamental plant of the Asteraceae family, which widely cultivated not only for its decorative use, but also extraction lutein. Besides carotenoid representatives, have been extensively studied, other important classes secondary metabolites present in plant, such as polyphenols, could exhibit biological activities. The phytochemical analysis methanolic extract obtained from T. inflorescences was achieved using liquid chromatography–mass spectrometry (LC-MS)...
In recent years, phytofunctionalized AgNPs have attracted great interest due to their remarkable biological activities. the present study, were synthesized using Abies alba and Pinus sylvestris bark extracts. The chemical profile of these extracts was analyzed by LC-HRMS/MS. As a first step, synthesis parameters (pH, AgNO3 concentration, ratio extract AgNO3, temperature, reaction time) optimized. characterized ATR-FTIR spectroscopy, DLS, SEM, EDX, TEM. Their antioxidant, cytotoxic,...
Abstract The present study evaluates the biosynthesis of AgNPs and AuNPs using aqueous ethanolic Geum urbanum L. rhizome extracts. biosynthesized metal nanoparticles (MNPs) were characterized UV-Vis spectroscopy, FTIR, DLS, SEM, EDX, TEM. spectra confirmed synthesis through peaks corresponding to surface plasmon effect metallic Ag (400–430 nm) Au (530–570 nm). FTIR analysis indicated that alcohols, phenols, proteins, carbohydrates from G. extracts composition are involved in MNPs synthesis....
This research describes an eco-friendly green route for the synthesis of AgNPs using aqueous extract Lythrum salicaria. Taguchi design was used to optimize method, taking into account various working conditions. The optimum parameters were established a 3 mM AgNO3 concentration, 1:9 extract:AgNO3 volume ratio, pH value 8, 60 ℃ temperature, and 180 min reaction time. synthesized characterized UV-Vis FTIR spectroscopy, TEM EDX analysis. SPR band at 410 nm, as well functional groups...
Taking into consideration the advantages of green synthesis nanoparticles, present study focuses on formation, characterization and evaluation some biological activities silver nanoparticles (AgNPs) obtained using bee propolis extract.The total phenolic flavonoid contents were evaluated.The formation AgNPs was primarily confirmed by change in colour appearance UV-Vis spectrum characteristic surface plasmon resonance band.Several compounds that can participate reduction process identified...
Zinnia elegans (syn. violacea) is a common ornamental plant of the Asteraceae family, widely cultivated for impressive range flower colors and persistent bloom. Given its uncomplicated cultivation high adaptability to harsh landscape conditions, we investigated potential use Z. as source valuable secondary metabolites. Preliminary classification compounds found in methanolic extract obtained from inflorescences cv. Caroussel was accomplished using HR LC-MS techniques. The then subjected...
Nanotechnology is one of the most studied domains, and nanoparticle synthesis, especially silver nanoparticles, has gained special importance due to their properties, biocompatibility applications. Today, processes nanoparticles synthesis tend toward development inexpensive, simple, non-toxic environmentally friendly methods. Thus, use plants in attracted considerable interest because biomolecules can act as both reducing stabilizing agents. This survey aims at discussing conditions for...
Black-eyed Susan (Rudbeckia hirta L.), a flowering plant with various traditional medicinal uses, has recently garnered interest for its therapeutic properties. However, little is known about the potential activities of species. The current study focused on conducting comprehensive investigation into chemical composition and bioactivity black-eyed cultivated in Romania. Untargeted metabolite profiling UHPLC-HR-MS phytochemical analysis studied extract revealed presence more than 250...
Artemisinin, a sesquiterpene lactone from Artemisia annua L., has received considerable attention in the last few decades as potent antimalarial drug. Artemisinin rather low toxicity; it is effective against drug-resistant Plasmodium species and cerebral malaria. This study reports development of rapid sensitive assay for quantification artemisinin A. by reversed phase HPLC/MS. In selected optimal experimental conditions, exhibited well-defined chromatographic peak with retention time 2 ±...
Inclusion complexes with sulfobutylether-β-cyclodextrin, β-cyclodextrin sulphated sodium salt and monochlorotriazinyl-β-cyclodextrin were characterized assessed for antifungal activity cytotoxicity.
The sterile stems belonging to the Equisetum species are often used in traditional medicine of various nations, including Romanians. They highly efficient treating urinary tract infections, cardiovascular diseases, respiratory and medical skin conditions due their content polyphenolic derivatives that have been isolated. In this regard, study aimed provide chemical composition extracts obtained from (E. pratense, E. sylvaticum, telmateia) investigate biological action vitro vivo. For...
The present study reports an eco-friendly synthesis method of silver nanoparticles (AgNPs) using two different extracts (aqueous and ethanolic) Tagetes erecta flowers. When exposed to biocompounds found in the plant, ions are reduced, thus, resulting green nanoparticles. After performing optimization synthesis, obtained AgNPs were characterized various techniques. UV–Vis spectrum synthesized showed maximum peaks at 410 420 nm. TEM analysis revealed that particles spherical with a size...
In the present study, two A. melanocarpa berry extracts were used for synthesis of silver nanoparticles (AgNPs). After optimization synthesis, AgNPs characterized using UV–Vis, FTIR, EDX, DLS, and STEM analyses. The stability in different media, phytotoxicity, as well antimicrobial antioxidant activities also evaluated. ideal conditions represented by a 3 mM AgNO3 concentration, 1:9 extract:AgNO3 volume ratio, alkaline medium, stirring at 40 °C 120 min. was confirmed surface plasmon...
The ethanolic extracts of three Equisetum species (E. pratense Ehrh., E. sylvaticum L. and telmateia Ehrh.) were used to reduce silver ions nanoparticles (AgNPs). synthesized AgNPs characterized using UV-Vis spectrophotometry, Fourier Transform Infrared Spectroscopy (FTIR), Energy Dispersive X-ray (EDX), Transmission Electron Microscopy (TEM) Dynamic Light Scattering (DLS) measurements. FTIR data revealed the functional groups biomolecules involved in synthesis, such as O-H, C-H, C=O, C-O,...
The aim of the study was to evaluate antibacterial activity and surface hardness a light-activated microhybrid composite resin modified with green silver nanoparticles (AgNPs). AgNPs were synthesized using an Equisetum sylvaticum extract characterized through different methods such as UV-Vis, EDX, FTIR. obtained mixed (Herculite XRV, Kerr Corp., Orange, CA, USA) in concentrations: 0% (group A-control); 0.5% B); 1% C); 1.5% D). A total 120 disk-shaped samples divided into 4 groups (n = 30)...
The aim of this study was the identification and quantification biologically active compounds from three Artemisia species, used as remedies in Romanian traditional medicine. A new LC-MS method developed for analysis methoxylated flavones also caffeic chlorogenic acids performed. antioxidant activity plant extracts evaluated by DPPH radical scavenging assay. paper reports first time presence eupatorin hispidulin A. absinthium vulgaris , eupatilin annua casticin . Jaceosidin acacetin were not...
In this study, we proposed formulations of diminazene aceturate (DA) designed to improve its bioavailability and maximize the therapeutic index in animals by overcoming rapid degradation under acidic pH stomach. An important consequence is fact that amount bloodstream close administered dose. This was made possible incorporating DA into β-cyclodextrin's (βCD) cavity a molar ratio 1:1. The structure resulted inclusion complex established Raman, DSC, Wide-Angle X ray Diffraction (WAXD) solid...