- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Phytochemicals and Antioxidant Activities
- Medicinal Plants and Neuroprotection
- Cholinesterase and Neurodegenerative Diseases
- Medicinal plant effects and applications
- Olfactory and Sensory Function Studies
- Natural product bioactivities and synthesis
- Nanoparticles: synthesis and applications
- Alzheimer's disease research and treatments
- Tea Polyphenols and Effects
- Garlic and Onion Studies
- Sesquiterpenes and Asteraceae Studies
- Natural Products and Biological Research
- Phytochemistry Medicinal Plant Applications
- Seaweed-derived Bioactive Compounds
- Piperaceae Chemical and Biological Studies
- Zebrafish Biomedical Research Applications
- Phytochemicals and Medicinal Plants
- Botany and Plant Ecology Studies
- Polysaccharides and Plant Cell Walls
- Neuroinflammation and Neurodegeneration Mechanisms
- Heavy Metals in Plants
- Herbal Medicine Research Studies
- Food Quality and Safety Studies
Grigore T. Popa University of Medicine and Pharmacy
2016-2025
Curcuma longa Linnaeus and Zingiber officinale Roscoe are two main representatives of Zingiberaceae family studied for a wide range therapeutic properties, including: antioxidant, anti-inflammatory, anti-angiogenic, antibacterial, analgesic, immunomodulatory, proapoptotic, anti-human immunodeficiency virus properties anticancer effects. This study was aimed to analyse the ethanolic extracts rhizome (Curcuma Linnaeus) (Zingiber Roscoe) in terms polyphenols, antioxidant activity anti-melanoma...
Ephedra alata Decne. belongs to the Ephedraceae family. It is a species of that grows mostly in desert. Today, main importance medical field due presence alkaloids derived from phenyl-alanine, which act on sympathetic nervous system as sympathomimetic. The aim this study was conduct phytochemical characterization hydroalcoholic extract aerial part Decne., indigenous Tunis, involves total phenolic content, individual and antioxidant activity well biological screening for evaluation...
The most prevalent neurodegenerative disease is Alzheimer's dementia. It determined by the deposits of amyloid-beta peptide which leads to memory impairment, oxidative stress, and neurodegeneration. Aromatherapy using essential oils could represent a natural treatment option for Therefore, this study aimed identify neuroprotective nootropic effects Pinus halepensis oil (PNO, 1% 3%, administered three weeks) in rat model acute amyloid beta (1-42) (Aβ1-42) toxicity. Rats were behaviorally...
Tribulus terrestris L. (Tt) has been recently gaining attention for its pharmacological value, including neuroprotective activities. In this study, we explore the effects of a extract in zebrafish (Danio rerio) model scopolamine (SCOP)-induced memory impairment and brain oxidative stress. SCOP, an anticholinergic drug, was employed to replicate fundamental aspects Alzheimer’s disease (AD) animal models. The fish were treated with ethanolic leaf (ELE) from Tt (1, 3, 6 mg/L) 15 days. SCOP (100...
Piper nigrum L. (Piperaceae) is employed in traditional medicine of many countries as analgesic, antiinflammatory, anticonvulsant, antioxidant, antidepressant and cognitive-enhancing agent. This study was undertaken order to evaluate the possible anxiolytic, antioxidant properties methanolic extract fruits beta-amyloid (1–42) rat model Alzheimer’s disease. The anxiolytic- antidepressant-like effects were studied by means vivo (elevated plus-maze forced swimming tests) approaches. Also,...
Tagetes erecta L. is a popular ornamental plant of the Asteraceae family, which widely cultivated not only for its decorative use, but also extraction lutein. Besides carotenoid representatives, have been extensively studied, other important classes secondary metabolites present in plant, such as polyphenols, could exhibit biological activities. The phytochemical analysis methanolic extract obtained from T. inflorescences was achieved using liquid chromatography–mass spectrometry (LC-MS)...
Albizia adianthifolia (Schumach.) W. Wright (Fabaceae) is a traditional herb largely used in the African medicine as analgesic, purgative, anti-inflammatory, antioxidant, antimicrobial and memory-enhancer drug. This study was undertaken order to evaluate possible cognitive-enhancing antioxidative effects of aqueous extract A. leaves 6-hydroxydopamine-lesion rodent model Parkinson's disease. The effect (150 300 mg/kg, orally, daily, for 21 days) on spatial memory performance assessed using...
Healthy dietary patterns during pregnancy are crucial for ensuring maternal and foetal health outcomes. Numerous methodologies exist assessing the diet of pregnant women, including various appraisal tools quality. This study aimed to assess quality women investigate relationship between patterns, estimators, adequacy nutrient intake. EPIC FFQ was applied a sample 251 questionnaires were interpreted with FETA program. Dietary then determined by means principal component analysis. Our results...
Background: The skin represents the first barrier of defence, and its integrity is crucial for overall health. Skin wounds present a considerable risk seeing how their progression rapid sometimes they are caused by comorbidities like diabetes venous diseases. Nutraceutical combinations ones between polyphenols metal ions applications thanks to increased bioavailability ability modulate intrinsic molecular pathways.; Methods: research findings presented in this paper based on systematic...
Nanoparticles (NPs) have revolutionized biomedical and pharmaceutical applications due to their unique physicochemical properties. However, widespread use has raised concerns regarding potential toxicity, particularly through oxidative stress mechanisms. Oxidative stress, primarily driven by reactive oxygen species (ROS) overproduction, plays a central role in NP-induced leading cellular dysfunction, inflammation, apoptosis, genotoxicity. Zebrafish (Danio rerio) emerged as powerful vivo...