A5052142908- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Phytochemicals and Antioxidant Activities
- Heavy Metals in Plants
- Medicinal Plants and Neuroprotection
- Ethnobotanical and Medicinal Plants Studies
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Marine Sponges and Natural Products
- Natural Antidiabetic Agents Studies
- Plant biochemistry and biosynthesis
- Microbial Natural Products and Biosynthesis
- Medicinal Plant Research
- Natural product bioactivities and synthesis
- Cholinesterase and Neurodegenerative Diseases
- Pharmacological Effects of Natural Compounds
- Plant Physiology and Cultivation Studies
- Allelopathy and phytotoxic interactions
- Food Science and Nutritional Studies
- Genomics, phytochemicals, and oxidative stress
- Drug-Induced Hepatotoxicity and Protection
- Skin Protection and Aging
- Garlic and Onion Studies
- Botany, Ecology, and Taxonomy Studies
- Agricultural and Rural Development Research
Kilis 7 Aralık University
2014-2025
Gaziantep University
2020-2025
Pediatrics and Genetics
2023
Faculty (United Kingdom)
2022
University of California, San Diego
2020
Bartin University
2018
Ordu University
2007-2011
Karadeniz Technical University
2005
A previously unreported bis-indolyl benzenoid, candidusin D (2e) and a new hydroxypyrrolidine alkaloid, preussin C (5b) were isolated together with fourteen described compounds: palmitic acid, clionasterol, ergosterol 5,8-endoperoxides, chrysophanic acid (1a), emodin (1b), six benzenoids including asterriquinol dimethyl ether (2a), petromurin (2b), kumbicin B (2c), (2d), 2″-oxoasterriquinol methyl (3), (4), the alkaloid (5a), (3S, 6S)-3,6-dibenzylpiperazine-2,5-dione (6) 4-(acetylamino)...
Background: The skin represents the first barrier of defence, and its integrity is crucial for overall health. Skin wounds present a considerable risk seeing how their progression rapid sometimes they are caused by comorbidities like diabetes venous diseases. Nutraceutical combinations ones between polyphenols metal ions applications thanks to increased bioavailability ability modulate intrinsic molecular pathways.; Methods: research findings presented in this paper based on systematic...
Atherosclerosis is a persistent inflammatory disorder influenced by oxidative stress and lipid imbalances, it continues to be major contributor cardiovascular diseases. Rich in catechins flavonoids, green tea pressurized hot water extract (GPHWE) demonstrated potent antioxidant activity through DPPH, ABTS, hydroxyl, nitric oxide scavenging assays. In vitro, GPHWE protected RAW264.7 macrophages from oxidized LDL (Ox-LDL)-induced cytotoxicity apoptosis mitigating enhancing cell survival....
Abstract: Background and Purpose: In recent years, essential oils (EOs) have been reported to possess interesting anti-tumor, anti-mutagenic anti-carcinogenic activities against various cancer cells. Therefore, we aimed investigate potential biological of EOs from white poplar (Populus alba L., Salicaceae) rosemary (Rosmarinus officinalis Lamiaceae). Material Methods: P. L. R. were extracted by hydrodistillation. MTT assay was carried out determine the antiproliferative cytotoxic properties...
Two new cyclotetrapeptides, sartoryglabramides A (5) and B (6), a analog of fellutanine (8) were isolated, together with six known compounds including ergosta-4, 6, 8 (14), 22-tetraen-3-one, ergosterol 5, 8-endoperoxide, helvolic acid, aszonalenin (1), (3R)-3-(1H-indol-3-ylmethyl)-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione (2), takakiamide (3), (11aR)-2,3-dihydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H,11aH)-dione (4), (7), from the ethyl acetate extract culture marine...
This study was carried out in the Eastern Black Sea region of Turkiye 2004. In study, botanical characteristics some wild edible plants, consumed abundantly region, such as Trachystemon orientalis, Similax excelsa, Ornithogalum umbellatum, Amaranthus retroflexus, Aegopodium podograria and Urtica diocia were firstly determined. Thereafter, chemical analyses performed order to determine nutritive values these plants. dry matter, crude oil, ash, protein, nitrogen, Cu, Mn, Fe, Zn vitamin C...
A previously unreported dihydrochromone dimer, paecilin E (1), was isolated, together with eleven known compounds: β-sitostenone, ergosta-4,6,8 (14), 22-tetraen-3-one, cyathisterone, byssochlamic acid, dehydromevalonic acid lactone, chevalone B, aszonalenin, dankasterone (2), helvolic secalonic and fellutanine A, from the culture filtrate extract of marine sponge-associated fungus Neosartorya fennelliae KUFA 0811. Nine reported metabolites, including a chromanol derivative (3), (3β, 5α,...
The extracts from 25 plant species Salvia, Hypericum, Onosma, Thymus, Origanum, Rosa, and Prunus with eight isolated compounds were screened for their memory-vitalizing potential against the enzymes, i.e., acetylcholinesterase (AChE), butyrylcholinesterase (BChE), tyrosinase (TYR) along DPPH, DMPD, NO radicals iron-chelation capacity using spectrophotometric microtiter assays. n-hexane:dichloromethane (1:1) extract of Onosma nigricaule roots (63.18 ± 0.56%) ethyl acetate aerial parts...
Daily treatment of ovariectomized (OVX) ICR mice with puerarin, a glycosyl isoflavone isolated from the root bark Pueraria candollei var. mirifica, and 17β-estradiol attenuated ovariectomy-induced depression-like behavior, as indicated by decrease in immobility times tail suspension test (TST) forced swimming (FST), an increase uterine weight volume, serum corticosterone levels, dose-dependently normalized downregulated transcription brain-derived neurotrophic factor (BDNF) estrogen receptor...
Çin'de başlayan ve pek çok ülkeye yayılan Covid-19, ‘Koronavirüs Pandemisi’ olarak dünya çapında bütün insanlığı tehdit eden bir salgın hastalık haline gelmiştir. Virüsün insandan insana hızlıca bulaşması yüksek ölüm oranına sahip olması, standart terapi protokollerinin geliştirilmesi onaylanması için acil ihtiyaç ortaya çıkarmıştır. Etkili tedavi stratejilerinin geliştirilebilmesi için; virüsün yapısal özellikleri, biyolojisi konak hücredeki enfeksiyon mekanizmaları tam bilinmelidir....
Abstract BACKGROUND: Medicinal plants commonly used and traded in Turkey were monitored for their cadmium selected micronutrient (copper, iron, manganese zinc) content. RESULTS: Cadmium was not detected any sample of licorice extract, linden flowers or nettle leaves. However, the rest samples, found range 7–126 µg kg −1 , with highest concentration chamomile leaf. Of all trace elements, 520 mg iron zahter. The copper, zinc concentrations rose hips (24 ), Turkish oregano (58 ) zahter (50...
Abstract: MicroRNAs (miRNAs) are highly conserved non-protein coding small RNAs, known to contribute the epigenetic regulation process in various cancer cells, including of progression, proliferation and metastasis differentiation cells apoptosis. In addition to, they crucial for stem management epithelial mesenchymal transition implicating cells. Further this, their roles changeable depending on biological processes, example miR-17, miR-20a, miR-19b-1, miR-18a, miR-19a, miR-92-1, miR-21,...