A5091216509- Cholinesterase and Neurodegenerative Diseases
- Computational Drug Discovery Methods
- Phytochemicals and Antioxidant Activities
- Phytochemistry and Biological Activities
- Essential Oils and Antimicrobial Activity
- Medicinal Plants and Neuroprotection
- Chemical synthesis and alkaloids
- Natural product bioactivities and synthesis
- Synthesis and biological activity
- melanin and skin pigmentation
- Free Radicals and Antioxidants
- Pharmacological Effects of Natural Compounds
- Bioactive natural compounds
- Natural Antidiabetic Agents Studies
- Biochemical and biochemical processes
- Bee Products Chemical Analysis
- Allelopathy and phytotoxic interactions
- Insect Pest Control Strategies
- Plant chemical constituents analysis
- Plant biochemistry and biosynthesis
- Skin Protection and Aging
- Medicinal plant effects and applications
- Alkaloids: synthesis and pharmacology
- Chromatography in Natural Products
- Traditional and Medicinal Uses of Annonaceae
Gazi University
2016-2025
Gazi Hastanesi
2018-2024
Premier University
2020
Central European University
2017
Background: Reynoutria japonica Houtt. has been used for inflammatory diseases, skin burns, and high cholesterol in traditional Chinese medicine, the roots rhizomes of plant were registered Pharmacopoeia. This study evaluated enzyme inhibitory activities R. extracts from Türkiye. Its major phytochemical content was elucidated, molecular interaction studies main compounds conducted, toxicokinetic predictions absorption, distribution, metabolism, elimination performed with silico methods....
In this study, p-tert-butyl at position 2 and acetamide bridged 4-substituted piperazine/piperidine 5 bearing benzoxazole derivatives were evaluated for their in vitro inhibitory activity against AChE, BChE Tyrosinase, which are important targets reducing the adverse effects of Alzheimer's disease. The most active 1 g inhibited a concentration 50 µM by 54 ± 0.75%. Molecular docking studies compounds (PDB: 4BDS) performed with Schrödinger AutoDock Vina results compared. scores found to be...
The dichloromethane (DCM), acetone, ethyl acetate and methanol extracts of the leaves berries Myrtus communis L. were screened against acetylcholinesterase (AChE), butyrylcholinesterase (BChE) tyrosinase (TYRO), enzymes linked to neurodegenerative diseases, at 200 μg ml− 1. Antioxidant activity was tested using radical scavenging 2,2-diphenyl-1-picrylhydrazyl (DPPH) N,N- dimethyl-p-phenylenediamine (DMPD) radicals, metal chelation capacity, ferric-reducing antioxidant power (FRAP)...
Background: Acne is a prevalent dermatological condition characterized by the blockage of hair follicles and sebaceous glands, leading to formation acne. The anaerobe pathogen Cutibacterium acnes (formerly known as Propionibacterium acnes) plays an essential role in pathogenesis acne, for which generally antimicrobial treatment required. substantial health concern, continuing research being conducted discover novel efficacious remedies. activity plants has been demonstrated numerous studies,...