A5000171415- Medicinal Plants and Neuroprotection
- Phytochemistry and Biological Activities
- Cholinesterase and Neurodegenerative Diseases
- Tryptophan and brain disorders
- Ethnobotanical and Medicinal Plants Studies
- Alkaloids: synthesis and pharmacology
- Natural product bioactivities and synthesis
- Moringa oleifera research and applications
- Stress Responses and Cortisol
- Ziziphus Jujuba Studies and Applications
- Medicinal Plant Extracts Effects
- Natural Antidiabetic Agents Studies
- Hibiscus Plant Research Studies
- African Botany and Ecology Studies
- Medicinal Plants and Bioactive Compounds
- Animal Disease Management and Epidemiology
- Bioactive Compounds and Antitumor Agents
- GABA and Rice Research
- Neuroscience and Neuropharmacology Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Ginkgo biloba and Cashew Applications
- Pharmaceutical and Antibiotic Environmental Impacts
- Estrogen and related hormone effects
- Morinda citrifolia extract uses
- Phytoestrogen effects and research
University of Maroua
2012-2024
Centre National de la Recherche Scientifique et Technologique
2020
Grigore T. Popa University of Medicine and Pharmacy
2020
Université Joseph Ki-Zerbo
2020
Institut de Recherche en Sciences de la Santé
2020
Romanian Academy
2020
Université de Yaoundé I
2004-2007
The aim of this work was to contribute our knowledge the proximate composition, mineral and vitamin content 20 edible wild plants used as spices in Cameroon. plant species were collected from 3 different markets West Region Cameroon analysed for their crude proteins, lipid, ash, moisture, available sugars, total phenols, carotenoids, minerals (Ca, Zn, K, Na, Mg, Al, Mn, Cu Se), vitamins (A, E C) well pH colour. Results revealed that all low moisture (7.7 10.5 g/100 g) but high ash g). Hua...
E. coccinae (SIMS) G. (Asteraceae) is an annual plant commonly found throughout the plain of Central Africa and widely used in Cameroonian folk medicine for treatment fever convulsions children. We previously reported that methanolic extract this improved spatial memory. However no underlying mechanism was explored. The present study undertaken to investigate effects hydroalcoholic Emilia on memory scopolamine treated rats propose possible mechanisms action. Novel object recognition Y-maze...
Vitellaria paradoxa is a traditional medicinal plant of Cameroon. Several studies on this have focused the cosmetic profile its fruits. The present study focuses anti-inflammatory potency stem barks extract plant.The objective was to evaluate effect methanolic V. (VPME) inflammatory response in rats.Anti-inflammatory effects VPME were evaluated acute and chronic (28 days) inflammation induced Wistar albino rats. hyperalgesia locomotors activity also quantified. relative weight lymphoid...
Albizia adianthifolia (Schumach.) W. Wright (Fabaceae) is a traditional herb largely used in the African medicine as analgesic, purgative, anti-inflammatory, antioxidant, antimicrobial and memory-enhancer drug. This study was undertaken order to evaluate possible cognitive-enhancing antioxidative effects of aqueous extract A. leaves 6-hydroxydopamine-lesion rodent model Parkinson's disease. The effect (150 300 mg/kg, orally, daily, for 21 days) on spatial memory performance assessed using...
Albizia adianthifolia (Schumach.) (Fabaceae) is a medicinal herb used for the treatment of epilepsy and memory impairment. This study aims to investigate anticonvulsant effects aqueous extract against pentylenetetrazole (PTZ)-induced spontaneous convulsions in mice; determine whether could mitigate impairment, oxidative/nitrergic stress, GABA depletion neuroinflammation. Ultra-high performance liquid chromatography/mass spectrometry analysis was done identify active compounds from extract....
Stress, regardless of its nature is nowadays recognized as one the major risk factors for neuropsychiatric diseases, such mood and anxiety disorders. The brain compared with other organs more vulnerable to oxidative damage mainly due high rate oxygen consumption, abundant lipid content, relative insufficiency antioxidant enzymes. Thus, identification neural mechanisms underlying resistance vulnerability stress crucial importance in understanding pathophysiology disorders developing new...
While the Albizia adianthifolia (Schumach.) W. Wright (Fabaceae) is a traditional herb largely used in African medicine as analgesic, purgative, antiinflammatory, antioxidant, antimicrobial, memory-enhancer, anxiolytic and antidepressant drug, there are no scientific data that clarify antidepressant-like effects 6-hydroxydopamine (6-OHDA)-lesioned animal model of Parkinson's disease. This study was undertaken order to identify aqueous extract A. leaves on 6-hydroxydopamine-induced anxiety,...
Ziziphus mucronata Willd, also known as “buffalo thorn,” belongs to the family Rhamnaceae. Its bark and leaves are used in folk medicine for treatment of various deficiencies related nociception, inflammation, mood, depression. Still, there is a lack scientific data regarding its potential effect on learning memory process. The present study was designed investigate neuroprotective (ZM) impairment scopolamine-induced model dementia mice. phytochemical analysis revealed five cyclopeptide...
The present study examined the anxiolytic and antidepressant effects of aqueous extract Alafia multiflora Stapf (AM) stem barks (150 300 mg/kg, 7 days administration) on rats mice, using experimental paradigms anxiety depression. In open field, increased significantly number center square crossed time spent at field as well rearing time, while grooming was reduced significantly. elevated plus maze, entries in arms. All these were also completely reversed by flumazenil, an antagonist...
The present study was undertaken to assess the anti-inflammatory potential of aqueous and methanolic extracts Hibiscus asper Hook. f. leaves (Malvaceae) against carrageenan induced acute inflammation complete Freund’s adjuvant (CFA)-induced arthritis in Wistar albino rats. In carrageenan-induced inflammation, extract H. exhibited significant antiinflammatory effect at dose 200 400 mg/kg. Maximum inhibition (57.29%) noted mg/kg after 2 h drug treatment while with extract, maximum (46.36%)...
We evaluated the anxiolytic and antidepressant effects of aqueous extract bark Tapinanthus dodoneifolius (TAE) (Danser) (25, 50, 100 mg/kg), using open field, elevated plus maze, forced swimming tests. Effect TAE was compared to standard drugs diazepam (2 mg/kg) imipramine (10 mg/kg). Additionally, same doses were on rat's memory Y-maze task. Results showed a significant (P < 0.05; increase in percentage arm entry time spent arms suggesting an activity extract. In dose-dependant manner, at...
This study evaluates the quality of veterinary drugs most frequently used in Far North Region Cameroon and describes how pastoralists use them to treat their cattle herds. High-performance liquid chromatography was identify quantify active ingredients (penicillin G, levamisole, oxytetracycline, diminazene diaceturate, vitamin A, E acetate) gas mass spectrometry determine if organic chemical contaminants were present. The results showed that 69% surveyed medicines common illnesses. In...
Guiera senegalensis JF Gmel. (Combretaceae) (GS) is a plant used in traditional medicine West Africa for the treatment of several diseases, such as epilepsy and depression. However, its potential benefits improving scopolamine (Sco)-induced memory impairment brain oxidative stress zebrafish have been investigated. In present study, (Danio rerio) were treated with GS (1, 4, 8 μg/L) 19 days well Sco (100 µM) 30 min before behavioral tests. Behavioral performance was assessed by Y-maze test...
The contamination of food by chemical hazards is a worldwide public health concern and leading cause trade problems internationally. Based on former work describing the prevalent use misuse antibiotics in cattle Far North Region Cameroon, we designed study to detect antibiotic (penicillin G oxytetracycline) beef sold for human consumption Maroua (Cameroon). To determine mean concentration residues beef, sample liver muscle were collected from 202 selected randomly all slaughterhouses Godola...
Plants used in the Far North Region of Cameroon by livestock farmers to manage foot and mouth disease (FMD) cattle phytochemical composition antioxidant potentials two them (Boscia senegalensis [BS] Tapinanthus dodoneifolius [TD]) were investigated this study.Ethno veterinary data collected from 325 using semi-structured interviews September 2011 April 2012. The 2,2-diphenyl-picrylhydrazyl radical scavenging activity total phenolic content (TPC) first performed with five different solvents...