A5077973125- Medicinal Plants and Neuroprotection
- Phytochemistry and Biological Activities
- Neuroscience and Neuropharmacology Research
- Chemical synthesis and alkaloids
- Ethnobotanical and Medicinal Plants Studies
- Alkaloids: synthesis and pharmacology
- Natural Antidiabetic Agents Studies
- Medicinal Plant Extracts Effects
- Botany, Ecology, and Taxonomy Studies
- Medicinal Plants and Bioactive Compounds
- Pharmacological Effects of Natural Compounds
- Plant-based Medicinal Research
- Cholinesterase and Neurodegenerative Diseases
- Essential Oils and Antimicrobial Activity
- African Botany and Ecology Studies
- Epilepsy research and treatment
- Animal Ecology and Behavior Studies
- Biochemical Analysis and Sensing Techniques
- Traditional and Medicinal Uses of Annonaceae
- Natural Compound Pharmacology Studies
- Seed and Plant Biochemistry
- Moringa oleifera research and applications
- Phytochemistry and biological activity of medicinal plants
- Pharmacological Effects and Toxicity Studies
- Biochemical effects in animals
University of Maroua
2015-2025
University of Ngaoundéré
2015-2024
Université de Dschang
2017
Alzheimer’s disease is first characterised by memory loss related to the central cholinergic system alteration. Available drugs provide symptomatic treatment with known side effects. The present study aimed evaluate properties of Carissa edulis aqueous extract on a Scopolamine mouse model as an attempt search for new compounds against disease-related impairment. Memory impairment was induced administration 1 mg/kg (i.p.) 7 days, and mice were treated extract. Behavioural studies performed...
Context: Nauclea latifolia Smith (Rubiaceae) is a small tree found in tropical areas Africa. It used traditional medicine to treat malaria, epilepsy, anxiety, pain, fever, etc.
Alzheimer's disease the most common form of dementia in elderly is a neurodegenerative that affects 44 millions people worldwide. The first treatments against are acetylcholinesterase inhibitors; however, these medications associated with many side effects. Dichrocephala integrifolia traditional herb widely used by indigenous population Cameroon to treat and prevent for memory improvement. In this study, we evaluated effect decoction prepared from leaves D. integrifolia, on...
African trypanosomes are mainly transmitted through the bite of tsetse flies (Glossina spp.). The present study investigated occurrence pathogenic in and cattle fly-infested areas Northern Cameroon.
The over-stimulation of N-methyl-d-aspartate glutamate receptors causes an excitotoxic neuronal death which plays important role in many neurodegenerative diseases. Carissa edulis, a medicinal plant used African pharmacopeia has been shown to have therapeutic effects. In this study, the effects edulis aqueous extract on L-glutamic acid-induced neurotoxicity mice were investigated. Two-month-old received intraperitoneal injection acid (2 g/kg) for seven consecutive days and treated with...
M. foetida (Cucurbitaceae) is a perennial climbing herb, known in traditional medicine for the treatment of certain diseases, such as malaria, headaches, skin-related problems and many others. The objective this work was to evaluate antidepressant effect aqueous lyophilisate mixture leaves stem foetida. at different doses (25 mg/kg, 50 mg/kg 75 mg/kg) evaluated Wistar rats both sexes submitted chronic restriction 14 days, using forced swimming test, open field test sucrose preference test....
This study aimed to investigate the anticonvulsant and anti-amnesic effects of Crassocephalum bauchiense aqueous extract in pilocarpine model temporal lobe epilepsy. Mice were treated for seven consecutive days as follows: one normal group negative control that received orally distilled water; four test groups doses (28, 70, 140 280 mg/kg), respectively; positive intraperitoneally 300 mg/kg sodium valproate. One hour after first treatment (first day), status epilepticus was induced by...
Cissus quadrangularis (C. quadrangularis) is a plant of the Vitaceae family known for its anticonvulsant effects in traditional medicine. The objective this study was to elucidate anxiolytic and antiepileptic aqueous extract C. quadrangularis. mice were divided into different groups treated seven consecutive days as follows: negative control group that received distilled water, po, four test doses (37.22, 93.05, 186.11, 372.21 mg/kg, po), positive sodium valproate (300 ip). One hour after...
The root of the matter: analgesic tramadol has been isolated from bark N. latifolia, an African medical plant. This finding is a rare example common synthetic drug that occurs at considerable concentrations in nature. Cl purple, N blue, O red. As service to our authors and readers, this journal provides supporting information supplied by authors. Such materials are peer reviewed may be re-organized for online delivery, but not copy-edited or typeset. Technical support issues arising (other...
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In this study, we investigated antiepileptogenic and neuroprotective effects of the aqueous extract Pergularia daemia roots (PDR) using in vivo vitro experimental models. studies, status epilepticus caused by pilocarpine injection triggers epileptogenesis which evolves during about 1-2 weeks. After 2 h epilepticus, mice were treated period for 7 days with sodium valproate vitamin C (standards demonstrated to alter epileptogenesis), or daemia. The animals then, 1 week after challenged acute...