A5008619991- Medicinal Plants and Neuroprotection
- Alkaloids: synthesis and pharmacology
- Pharmacological Effects of Natural Compounds
- Cholinesterase and Neurodegenerative Diseases
- Phytochemistry and Biological Activities
- Traditional and Medicinal Uses of Annonaceae
- Olfactory and Sensory Function Studies
- Neuroscience and Neuropharmacology Research
- Ethnobotanical and Medicinal Plants Studies
- Phytoestrogen effects and research
- Memory and Neural Mechanisms
- GABA and Rice Research
- Medicinal Plant Extracts Effects
- Alzheimer's disease research and treatments
- Cancer-related cognitive impairment studies
- Antioxidants, Aging, Portulaca oleracea
University of Buea
2020-2021
University of Ngaoundéré
2015-2018
Alzheimer's disease the most common form of dementia in elderly is a neurodegenerative that affects 44 millions people worldwide. The first treatments against are acetylcholinesterase inhibitors; however, these medications associated with many side effects. Dichrocephala integrifolia traditional herb widely used by indigenous population Cameroon to treat and prevent for memory improvement. In this study, we evaluated effect decoction prepared from leaves D. integrifolia, on...
Cissus quadrangularis (C. quadrangularis) is a plant of the Vitaceae family known for its anticonvulsant effects in traditional medicine. The objective this study was to elucidate anxiolytic and antiepileptic aqueous extract C. quadrangularis. mice were divided into different groups treated seven consecutive days as follows: negative control group that received distilled water, po, four test doses (37.22, 93.05, 186.11, 372.21 mg/kg, po), positive sodium valproate (300 ip). One hour after...
Aim . To assess memory improvement and neuroprotective antioxidant effects of Mitragyna inermis ( M. ) leaf decoction on the central nervous system. Methodology Leaf was tested learning in normal scopolamine-induced cognitive impairment mice using behavioral tests such as Morris water maze, object recognition task, elevated plus maze. Oxidative stress enzymes—catalase, superoxide dismutase, thiobarbituric acid reactive substance, a product lipid peroxidation—were quantified. In each test, 18...
Leptadenia arborea (Asclepiadaceae) is a plant used in traditional medicine to treat syphilis, migraine, and mental illnesses. The aim of our study was investigate possible antidepressant anti-amnesic effects the aqueous lyophilisate leaves an animal model cognitive deficit associated depression. Swiss albino adult mice both sexes were for this study. A 14-day combined stress induce depression with early deficits. forced swimming test, open field test plasma corticosterone level assess...
The aim of our study was to evaluate the anti-amnesic and cerebral protective effects Mitragyna inermis determine its toxic or non-toxic effects.We used rota rod open field tests for motor coordination memory.We also biochemical oxidative stress such as catalase, superoxide dysmutase malondialdehyde tests.We finally toxicity evaluation number mice rats died, determination alanine amino transferase, aspertate transferase quantification blood cells (white red cells, platelets).We found that M....
The objective of our study was to evaluate the anti-Alzheimer activities Mitragyna inermis leaf decoction against scopolamine, D-galactose and atropineinduced Alzheimer likes effects in mice.Mitragyna leaves used memory lost, which is characterized by elevation acetylcholinesterase butyrylcholinesterase induced Dgalactose atropine.For this study, we behavioral tests such as Elevated Plus maze Open field tests, biochemical were determination AChE BChE activities.In all mice 18 25 g divided...