- Nanoparticles: synthesis and applications
- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Phytochemistry and Biological Activities
- Moringa oleifera research and applications
- Natural product bioactivities and synthesis
- Phytochemistry and Bioactivity Studies
- Pharmacological Effects of Natural Compounds
- Sesquiterpenes and Asteraceae Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- Laser-Ablation Synthesis of Nanoparticles
- Plant Toxicity and Pharmacological Properties
- Insect Pest Control Strategies
- Medicinal Plants and Neuroprotection
- Tea Polyphenols and Effects
- Food Quality and Safety Studies
- Allelopathy and phytotoxic interactions
- Pesticide Exposure and Toxicity
- Zebrafish Biomedical Research Applications
- Computational Drug Discovery Methods
- Advanced Drug Delivery Systems
- Neuroinflammation and Neurodegeneration Mechanisms
- Nanoparticle-Based Drug Delivery
- Cholinesterase and Neurodegenerative Diseases
- Complementary and Alternative Medicine Studies
Grigore T. Popa University of Medicine and Pharmacy
2017-2024
Tagetes erecta L. is a popular ornamental plant of the Asteraceae family, which widely cultivated not only for its decorative use, but also extraction lutein. Besides carotenoid representatives, have been extensively studied, other important classes secondary metabolites present in plant, such as polyphenols, could exhibit biological activities. The phytochemical analysis methanolic extract obtained from T. inflorescences was achieved using liquid chromatography–mass spectrometry (LC-MS)...
Nanoparticles (NPs) have revolutionized biomedical and pharmaceutical applications due to their unique physicochemical properties. However, widespread use has raised concerns regarding potential toxicity, particularly through oxidative stress mechanisms. Oxidative stress, primarily driven by reactive oxygen species (ROS) overproduction, plays a central role in NP-induced leading cellular dysfunction, inflammation, apoptosis, genotoxicity. Zebrafish (Danio rerio) emerged as powerful vivo...
This study explores the complexities involved in extraction and purification of catechins, prominent bioactive compounds found plant extracts tea. It addresses challenges arising from intricate molecular structure catechins their inherent variability across botanical sources. Despite these obstacles, present significant potential, particularly healthcare. Their potent antioxidant properties have been extensively investigated associated with numerous health benefits, positioning them as...
This review study explores the complex methods involved in extraction and purification of polyphenols, specifically catechins, prominent compounds that are bioactive found plant-based extracts foods like tea. also addresses challenges may arise from chemical structure catechins their inherent variability across botanical sources. Despite these shortcomings obstacles, catechin derivatives present significant potential, particularly healthcare but food industry. Their enhanced antioxidant...
Abstract The present study evaluates the biosynthesis of AgNPs and AuNPs using aqueous ethanolic Geum urbanum L. rhizome extracts. biosynthesized metal nanoparticles (MNPs) were characterized UV-Vis spectroscopy, FTIR, DLS, SEM, EDX, TEM. spectra confirmed synthesis through peaks corresponding to surface plasmon effect metallic Ag (400–430 nm) Au (530–570 nm). FTIR analysis indicated that alcohols, phenols, proteins, carbohydrates from G. extracts composition are involved in MNPs synthesis....
This research describes an eco-friendly green route for the synthesis of AgNPs using aqueous extract Lythrum salicaria. Taguchi design was used to optimize method, taking into account various working conditions. The optimum parameters were established a 3 mM AgNO3 concentration, 1:9 extract:AgNO3 volume ratio, pH value 8, 60 ℃ temperature, and 180 min reaction time. synthesized characterized UV-Vis FTIR spectroscopy, TEM EDX analysis. SPR band at 410 nm, as well functional groups...
Zinnia elegans (syn. violacea) is a common ornamental plant of the Asteraceae family, widely cultivated for impressive range flower colors and persistent bloom. Given its uncomplicated cultivation high adaptability to harsh landscape conditions, we investigated potential use Z. as source valuable secondary metabolites. Preliminary classification compounds found in methanolic extract obtained from inflorescences cv. Caroussel was accomplished using HR LC-MS techniques. The then subjected...
Black-eyed Susan (Rudbeckia hirta L.), a flowering plant with various traditional medicinal uses, has recently garnered interest for its therapeutic properties. However, little is known about the potential activities of species. The current study focused on conducting comprehensive investigation into chemical composition and bioactivity black-eyed cultivated in Romania. Untargeted metabolite profiling UHPLC-HR-MS phytochemical analysis studied extract revealed presence more than 250...
Y. schidigera contains a number of unusual polyphenols, derivatives resveratrol and naringenin, called spiro-flavostilbenoids, which have potent in vitro anti-inflammatory, antioxidant, moderate cholinesterase inhibitory activities. To date, these compounds not been tested vivo for the treatment neurodegenerative diseases. The aim present study was to evaluate effects both single spiro-flavostilbenoids (yuccaol B gloriosaol A) phenolic fractions derived from bark on scopolamine-induced...
The present study focuses on two ornamental species of the Asteraceae family and their biological properties, which can be correlated with presence different classes natural compounds.Given fact that secondary metabolites found in such plants used as valuable resources for pharmaceutical industry, we chose to investigate potential Chrysanthemum indicum Tagetes erecta inflorescences.Four types extracts were obtained each species, using organic solvents polarities.Bioactive compounds...
The sterile stems belonging to the Equisetum species are often used in traditional medicine of various nations, including Romanians. They highly efficient treating urinary tract infections, cardiovascular diseases, respiratory and medical skin conditions due their content polyphenolic derivatives that have been isolated. In this regard, study aimed provide chemical composition extracts obtained from (E. pratense, E. sylvaticum, telmateia) investigate biological action vitro vivo. For...
The present study reports an eco-friendly synthesis method of silver nanoparticles (AgNPs) using two different extracts (aqueous and ethanolic) Tagetes erecta flowers. When exposed to biocompounds found in the plant, ions are reduced, thus, resulting green nanoparticles. After performing optimization synthesis, obtained AgNPs were characterized various techniques. UV–Vis spectrum synthesized showed maximum peaks at 410 420 nm. TEM analysis revealed that particles spherical with a size...
In the present study, two A. melanocarpa berry extracts were used for synthesis of silver nanoparticles (AgNPs). After optimization synthesis, AgNPs characterized using UV–Vis, FTIR, EDX, DLS, and STEM analyses. The stability in different media, phytotoxicity, as well antimicrobial antioxidant activities also evaluated. ideal conditions represented by a 3 mM AgNO3 concentration, 1:9 extract:AgNO3 volume ratio, alkaline medium, stirring at 40 °C 120 min. was confirmed surface plasmon...
The ethanolic extracts of three Equisetum species (E. pratense Ehrh., E. sylvaticum L. and telmateia Ehrh.) were used to reduce silver ions nanoparticles (AgNPs). synthesized AgNPs characterized using UV-Vis spectrophotometry, Fourier Transform Infrared Spectroscopy (FTIR), Energy Dispersive X-ray (EDX), Transmission Electron Microscopy (TEM) Dynamic Light Scattering (DLS) measurements. FTIR data revealed the functional groups biomolecules involved in synthesis, such as O-H, C-H, C=O, C-O,...
The aim of the study was to evaluate antibacterial activity and surface hardness a light-activated microhybrid composite resin modified with green silver nanoparticles (AgNPs). AgNPs were synthesized using an Equisetum sylvaticum extract characterized through different methods such as UV-Vis, EDX, FTIR. obtained mixed (Herculite XRV, Kerr Corp., Orange, CA, USA) in concentrations: 0% (group A-control); 0.5% B); 1% C); 1.5% D). A total 120 disk-shaped samples divided into 4 groups (n = 30)...
Essential oils or volatile are natural products that have a large series of uses in the food and cosmetic sectors.According to their intended use, essential subjected various European guidelines aim protect health safety consumers.Volatile present important biological activities, some most known being antimicrobial properties, but other potential therapeutic indications for such been more recently suggested, as well.However, they not necessarily harmless can an sensitizing...
Abstract: Objective: This paper presents the results regarding morphological characters, content in total phenols, metabolites profile and antioxidant activity of outdoor cultivated Rudbeckia hirta var. Goldilocks Tagetes erecta plants. Material Methods: The plant material was represented by flower buds fully bloomed inflorescences taken from erecta. Morphological assessment carried using microscopy, while chemical used thin layer chromatography (TLC) UHPLC methods. phenolic established with...
This paper presents a simple and eco-friendly method for the synthesis of silver nanoparticles (AgNPs) using licorice (Glycyrrhiza glabra) root extract evaluation their antioxidant activity. UV-Vis spectroscopy, FTIR, TEM EDX methods were used to characterize AgNPs. The spectrum shows characteristic surface plasmon resonance peak at 430 nm. synthesized AgNPs have spherical shape are capped by biomolecules. Furthermore, FTIR spectra analysis demonstrate presence phytochemicals from which act...
This paper presents a simple and eco-friendly method for the synthesis of silver nanoparticles (AgNPs) using licorice (Glycyrrhiza glabra) root extract evaluation their antioxidant activity. UV-Vis spectroscopy, FTIR, TEM EDX methods were used to characterize AgNPs. The spectrum shows characteristic surface plasmon resonance peak at 430 nm. synthesized AgNPs have spherical shape are capped by biomolecules. Furthermore, FTIR spectra analysis demonstrate presence phytochemicals from which act...
Plant extracts have been pivotal in medicine and pharmacognosy for centuries, housing an array of bioactive compounds with therapeutic potential. This field, dedicated to exploring the medicinal properties natural products, delves into varied chemical compositions these extracts. From ancient remedies modern pharmaceuticals, they indispensable healthcare. Numerous drugs, including aspirin morphine, find their roots plant sources. Today, obtained from plants like ginseng, echinacea, turmeric...