C. Rîmbu

ORCID: 0000-0003-0982-0040
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About
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Research Areas
  • Essential Oils and Antimicrobial Activity
  • Antibiotic Resistance in Bacteria
  • Nanocomposite Films for Food Packaging
  • Animal Virus Infections Studies
  • Viral gastroenteritis research and epidemiology
  • Nanoparticles: synthesis and applications
  • Milk Quality and Mastitis in Dairy Cows
  • Electrospun Nanofibers in Biomedical Applications
  • Bee Products Chemical Analysis
  • Microbial infections and disease research
  • Probiotics and Fermented Foods
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Virus-based gene therapy research
  • Yersinia bacterium, plague, ectoparasites research
  • Aquaculture disease management and microbiota
  • Salmonella and Campylobacter epidemiology
  • biodegradable polymer synthesis and properties
  • Antimicrobial agents and applications
  • Natural product bioactivities and synthesis
  • Bioactive natural compounds
  • Aquaculture Nutrition and Growth
  • SARS-CoV-2 and COVID-19 Research
  • Clostridium difficile and Clostridium perfringens research
  • Dyeing and Modifying Textile Fibers
  • Hydrogels: synthesis, properties, applications

"Ion Ionescu de la Brad" Iasi University of Life Sciences
2015-2025

Alexandru Ioan Cuza University
2024

University of Agricultural Sciences, Dharwad
2014-2021

Spitalul Clinic C.F. Iasi
2019

Lucian Blaga University of Sibiu
2016

University of Agronomic Sciences and Veterinary Medicine of Bucharest
2015

Emulsion hydrogels are promising materials for encapsulating and stabilizing high amounts of hydrophobic essential oils in hydrophilic matrices. In this work, clove oil-loaded (CS/OP-C) synthesized by combining covalent physical cross-linking approaches. First, oil (CO) was emulsified stabilized a chitosan (CS) solution, which further hardened Schiff base with oxidized pullulan (OP). Second, the were subjected to freeze–thaw cycles and, as result, physically cross-linked polymeric walls....

10.3390/gels10040227 article EN cc-by Gels 2024-03-26

The aim of this study was to evaluate the antibacterial activity coriander essential oil and its major constituent, linalool, in combination with antibiotics against Gram-positive (methicillin-susceptible methicillin-resistant Staphylococcus aureus, S. epidermidis) Gram-negative bacteria (Pseudomonas aeruginosa, Escherichia coli). chemical composition analyzed by gas chromatography flame ionization mass spectrometry detection. oil, linalool their combinations were assessed broth...

10.1111/lam.13100 article EN Letters in Applied Microbiology 2018-11-24

In this study, we aim to obtain biomaterials with antibacterial properties by combining poly(vinyl alcohol) the extracts obtained from various selected plants Romania. Natural herbal of freshly picked flowers lavender plant (Lavandula angustifolia) and leaves peppermint (Mentha piperita), hemp (Cannabis sativa L.), verbena (Verbena officinalis) sage (Salvia officinalis folium) were after an intensive analyzing diverse medicinal often used as healing agents country flora. The characterized...

10.3390/ma15072493 article EN Materials 2022-03-28

The main strategy of this study was to combine the traditional perspective using medicinal extracts with polymeric scaffolds manufactured by an engineering approach fabricate a potential dressing product antimicrobial properties. Thus, chitosan-based membranes containing S. officinalis and H. perforatum were developed their suitability as novel materials investigated. morphology films assessed scanning electron microscopy (SEM) chemical structure characterization performed via Fourier...

10.3390/ijms24108673 article EN International Journal of Molecular Sciences 2023-05-12

The therapeutic efficiency of plant extracts has been limited by their poor pharmaceutical availability. Hydrogels have promising potential to be applied as wound dressings due high capacity absorb exudates and enhanced performance in loading releasing extracts. In this work, pullulan/poly (vinyl alcohol) (P/PVA) hydrogels were first prepared using an eco-friendly method based on both a covalent physical cross-linking approach. Then, the loaded with hydroalcoholic extract Calendula...

10.3390/pharmaceutics15061674 article EN cc-by Pharmaceutics 2023-06-07

Use of antibiotics in food animals may contribute to development and spread resistant organisms, particularly so some countries. The aim this study was two-fold; first, establish the prevalence extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli chicken production a region within Romania. Second, relatedness ESBL-producing E. isolates recovered from broilers, abattoir workers where chickens were slaughtered human clinical specimens two regional hospitals. results indicated...

10.1089/mdr.2014.0248 article EN Microbial Drug Resistance 2015-03-03

In recent years, phytofunctionalized AgNPs have attracted great interest due to their remarkable biological activities. the present study, were synthesized using Abies alba and Pinus sylvestris bark extracts. The chemical profile of these extracts was analyzed by LC-HRMS/MS. As a first step, synthesis parameters (pH, AgNO3 concentration, ratio extract AgNO3, temperature, reaction time) optimized. characterized ATR-FTIR spectroscopy, DLS, SEM, EDX, TEM. Their antioxidant, cytotoxic,...

10.3390/antiox12040797 article EN cc-by Antioxidants 2023-03-24

Colistin is a last resort antibiotic used for the treatment of human infections associated with carbapenemase-producing Enterobacteriales. Here, we evaluated occurrence mcr-1 and -2 plasmid-mediated colistin resistance in and/or carbapenem resistant clinical Enterobacteriales other gram-negative bacteria (n=543) as well 3rd generation cephalosporin-resistant (3GCR) Escherichia coli isolates from poultry abattoir workers (n=15) faecal samples (n=92) collected two geographically separate...

10.3389/fmicb.2019.02267 article EN cc-by Frontiers in Microbiology 2019-10-10

Silver nanoparticles synthesized using plant extracts as reducing and capping agents showed various biological activities. In the present study, colloidal silver nanoparticle solutions were produced from aqueous of Picea abies Pinus nigra bark. The phenolic profile bark was analyzed by liquid chromatography coupled to mass spectrometry. synthesis monitored UV-Vis spectroscopy measuring Surface Plasmon Resonance band. characterized attenuated total reflection Fourier transform infrared...

10.3390/molecules27010217 article EN cc-by Molecules 2021-12-30

Hydrogels based on biocompatible polysaccharides with biological activity that can slowly release an active principle at the wound site represent promising alternatives to traditional dressing materials. In this respect, new hydrogels curdlan derivative 2-hydroxypropyl dimethyl octyl ammonium groups (QCurd) and native (Curd) were obtained room temperature by covalent cross-linking using a diepoxy agent. The chemical structure of QCurd/Curd was investigated Fourier transform infrared...

10.3390/gels10070424 article EN cc-by Gels 2024-06-27

This article demonstrates that the quality of laundry soap obtained by hot/cold saponification two vegetable oils (olive and coconut) an essential oil (such as Neem, Tea Tree or Thyme) influences effects after washing textiles: cleansing capacity antibacterial effect. The results FTIR, SEM, EDX, thermogravimetry colorimetry analyses are presented comparatively for hot- cold-prepared soaps. Saponification, Iodine number Number Saponification values determined each but also mixture used in...

10.3390/app15073821 article EN cc-by Applied Sciences 2025-03-31

This minireview presents recent developments in surface nano-structured textiles and their biomedical applications by up-to-date achievements, summarizing the coatings made of biopolymer films nanoparticles on different textile substrates for enhanced medical applications, diminishing incidence multiple range hospital-acquired infections past 10 years. The combination metal oxide with biopolymers is an efficient technique to generate antibacterial, virucidal antifungal properties textiles....

10.1177/00405175211070613 article EN Textile Research Journal 2022-01-26

The majority of recent studies have focused on obtaining MRI materials for internal use. However, this study focuses a straightforward method preparing gelatin-based with iron oxide nanoparticles (G-Fe2O3 and G-Fe3O4) external newly obtained must be precisely tuned to match the requirements usage situation because they will in close touch human/animal skin. biocompatible structures formed by gelatin, tannic acid, were investigated using FTIR spectroscopy, SEM-EDAX analysis, contact angle...

10.3390/ma15103479 article EN Materials 2022-05-12

Abstract The present study evaluates the biosynthesis of AgNPs and AuNPs using aqueous ethanolic Geum urbanum L. rhizome extracts. biosynthesized metal nanoparticles (MNPs) were characterized UV-Vis spectroscopy, FTIR, DLS, SEM, EDX, TEM. spectra confirmed synthesis through peaks corresponding to surface plasmon effect metallic Ag (400–430 nm) Au (530–570 nm). FTIR analysis indicated that alcohols, phenols, proteins, carbohydrates from G. extracts composition are involved in MNPs synthesis....

10.1007/s10904-024-03189-y article EN cc-by Journal of Inorganic and Organometallic Polymers and Materials 2024-07-15

Palladium(II) complexes with Schiff bases ligands derived from salicylaldehyde and amino acids (Ala, Gly, Met, Ser, Val) have been synthesized characterized by Fourier transform (FT)-IR, UV-Vis 1H-NMR spectroscopy. The electrospray mass spectrometry (ES-MS) confirms the formation of palladium(II) in 1/2 (M/L) molar ratio. All Pd(II) 1, [Pd(SalAla)2]Cl2; 2, [Pd(SalGly)2]Cl2; 3, [Pd(SalMet)2]Cl2; 4, [Pd(SalSer)2]Cl2; 5, [Pd(SalVal)2]Cl2; shown antibacterial activity against Gram-positive...

10.1248/cpb.c12-01087 article EN Chemical and Pharmaceutical Bulletin 2013-12-31

In this work, the effects of salt stress on Nepeta racemosa Lam. were studied to analyze possibility using it as a potential culture for salinity-affected soils. A total nine concentrations salts—NaCl (18, 39, and 60 mg/100 g soil), Na2SO4 (50, 85, 120 mixture (9 NaCl + 25 Na2SO4, 19 43 30 Na2SO4/100 soil)—simulated real salinity conditions. Environmental electron microscopy offered information about size distribution glandular trichomes, which are very important structures that contain...

10.3390/plants12030583 article EN cc-by Plants 2023-01-29

In recent years, multidrug-resistant bacteria have developed the ability to resist multiple antibiotics, limiting available options for effective treatment. Raising awareness and providing education on appropriate use of as well improving infection control measures in healthcare facilities, are crucial steps address crisis. Further, innovative approaches must be adopted develop novel drug delivery systems using polymeric matrices carriers support efficiently combat such thus promote wound...

10.3390/gels9080655 article EN cc-by Gels 2023-08-14

Combination of antibiotics with natural products is a promising strategy for potentiating antibiotic activity and overcoming resistance. The purpose the present study was to investigate whether morusin kuwanon G, prenylated phenolics in Morus species, have ability enhance reverse resistance Staphylococcus aureus epidermidis. Commonly used (oxacillin, erythromycin, gentamicin, ciprofloxacin, tetracycline, clindamycin) were selected combination studies. Checkerboard time-kill assays potential...

10.1016/j.jsps.2020.08.006 article EN cc-by-nc-nd Saudi Pharmaceutical Journal 2020-08-18

Essential oil of Nepeta racemosa Lam. was extracted and characterized to determine its antimicrobial activity potential use in applications. The essential loaded on polyvinyl alcohol-pullulan films gels by optical microscopy, scanning electron UV-Vis spectroscopy before having capacities assessed. from using gas chromatography coupled with mass spectroscopy, which indicated that the most abundant component nepetalic acid (55.5%), followed eucalyptol (10.7%) other compounds concentrations...

10.3390/plants12040898 article EN cc-by Plants 2023-02-16

In this paper, hydroalcoholic solutions of Thymus vulgaris, Salvia officinalis folium, and Hyperici herba were used in combination with poly (vinyl alcohol) the aim developing novel alcohol)-based nanofiber mats loaded phytotherapeutic agents via electrospinning technique. The chemical structure morphology polymeric nanofibers investigated using Fourier Transform Infrared Spectroscopy (FTIR) Scanning Electron Microscopy (SEM). addition extracts to pure polyvinyl alcohol fibers led changes a...

10.3390/nano11123336 article EN cc-by Nanomaterials 2021-12-08
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