A5080631883- Hydrogels: synthesis, properties, applications
- biodegradable polymer synthesis and properties
- Nanocomposite Films for Food Packaging
- Synthesis and properties of polymers
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Advanced Drug Delivery Systems
- Advanced Polymer Synthesis and Characterization
- Surfactants and Colloidal Systems
- Liquid Crystal Research Advancements
- Polysaccharides Composition and Applications
- Additive Manufacturing and 3D Printing Technologies
- Advancements in Transdermal Drug Delivery
- Polymer Surface Interaction Studies
- Photochromic and Fluorescence Chemistry
- Supramolecular Self-Assembly in Materials
- Electrospun Nanofibers in Biomedical Applications
- Polymer-Based Agricultural Enhancements
- Antimicrobial agents and applications
- Sesquiterpenes and Asteraceae Studies
- Photopolymerization techniques and applications
- Legume Nitrogen Fixing Symbiosis
- Plasma Applications and Diagnostics
- Nanoparticle-Based Drug Delivery
- Wound Healing and Treatments
Romanian Academy
2017-2023
Institutul de Chimie Macromoleculară Petru Poni
2018-2020
In the context of increasing interest in biomaterials with applicability cosmetics and medicine, this research aims to obtain characterize some hybrid materials based on chitosan (CS) (antibacterial, biocompatible, biodegradable), poly(ethylene glycol) (PEG) (non-toxic prevents adsorption protein cell) Laponite® RD (Lap) (bioactive). The rheological properties starting dispersions were investigated discussed related interactions developed between components. All samples exhibited gel-like...
The paper reports a new mathematical model for understanding the mechanism delivery from drug release systems. To do this, two systems based on chitosan and diclofenac sodium salt as model, were prepared by in situ hydrogelation presence of salicylaldehyde. morphology was analyzed scanning electron microscopy polarized light
In recent years, multidrug-resistant bacteria have developed the ability to resist multiple antibiotics, limiting available options for effective treatment. Raising awareness and providing education on appropriate use of as well improving infection control measures in healthcare facilities, are crucial steps address crisis. Further, innovative approaches must be adopted develop novel drug delivery systems using polymeric matrices carriers support efficiently combat such thus promote wound...
Aromatic polyazomethines–containing azobenzene side groups have been synthesized by solution polycondensation reaction of aromatic dialdehydes bearing flexible spacers between the rings with diamines having preformed groups. Thermogravimetric analysis, differential scanning calorimetry, polarized optical microscopy, and wide angle X-ray diffraction used to evaluate their thermal mesomorphic properties. The target polyazomethines showed nematic liquid crystalline phase, large mesophase range,...
Three asymmetric azomethine-azobenzene intermediates (M1-M3), having internal reactive amine functional group, and both n-butoxy p-chloro, p-methyl, o-methyl terminal moieties, have been synthesised by reacting substituted azobenzene diamines with 4-butoxybenzaldehyde. Their proposed chemical structures were confirmed FTIR 2D-NMR spectroscopy. The mesomorphic behaviour was investigated polarised optical microscopy (POM), differential scanning calorimetry (DSC) room temperature powder X-ray...
Dynamic chitosan-based hydrogels with enhanced antioxidant activity were synthesized through the formation of reversible imine linkages 5-methoxy-salicylaldehyde. These exhibited a porous structure and swelling capacity, influenced by crosslinking degree, as confirmed SEM POM analysis. The dynamic nature bonds was characterized NMR, studies in various media, aldehyde release measurements. demonstrated significantly improved compared to unmodified chitosan, evaluated DPPH method. This...
The present paper focuses on the rheological behaviour of a series hydrogels prepared from chitosan and salicylaldehyde. unusual crosslinking with this monoaldehyde was assessed by 1H NMR spectroscopy, which demonstrated formation covalent imine bonds. exhibited super-porous morphology, evidenced SEM measurements, layered supramolecular structure sustained birefringence texture hydrogels, observed polarized light microscopy (POM). hydrogel-like confirmed rheologic measurements for sample...
This paper reports the calibration of a theoretical multifractal model based on empirical data urea release from series soil conditioner systems. To do this, formulations was prepared by in situ hydrogelation chitosan with salicylaldehyde presence different amounts. The were morphologically characterized scanning electron microscopy and polarized light microscopy. vitro investigated an environmentally simulated medium. fitted five mathematical models, Korsmeyer-Peppas, Zero order, First...
This study aimed to investigate the behavior of chitosan/quaternized chitosan fibers in media mimicking wound exudates understand their capacities as dressing. Fiber analysis using dynamic vapor sorption proved ability adsorb moisture up 60% and then desorb it a function humidity, indicating outstanding breathability. Dissolution analyses showed that quaternized leached from water PBS, whereas only small portions were solubilized water. In containing lysozyme, degraded with rate determined...
The paper reports new multifunctional plant biostimulant formulations obtained via in situ hydrogelation of chitosan with salicylaldehyde the presence a mimetic naphthalimide-based strigolactone, specific conditions. Various analytical techniques (FTIR,
Plasma-activated chitosan (PAC) colloids for cancer treatment were obtained by using the cold atmospheric plasma technique. Chitosan solutions irradiated ignited in argon gas and a mixture of with nitrogen oxygen gases certain ratios. The structural modifications chemical species generated investigated EPR, LC-MS/MS, XRD, DLS, TGA methods. cell viability test showed selective cytotoxic effect on human breast carcinoma cells (MCF-7), while mammary epithelial (MCF-10A) left unharmed. was...
The main objective of the paper was to prepare eco-friendly chiral hydrogels from chitosan and betulinic aldehyde under ultrasonic radiation effect, targeting their use for enantiomeric separations. This strategy promoted obtaining by supramoleclar organization imine units bonding betuline skeleton with into ordered clusteres, while not altering physico-chemical properties reagents. FTIR, SEM, CD spectroscopy POM techniques were used prove pelicularities hydrogelation mechanism...
This paper presents an alternative for enhancing the durability of poly (L-lactide) (PLLA) by racemic nucleation following stereo-complexation with a selected (D-lactide) (PLDA). The compounds are obtained melt blending PLLA grade, previously designed 3D printing but low heat deflection temperature and impact resistance, grades PLDA differing in their molecular weight (Mw), D-lactide content (DS) concentration. Our method considered how to reveal caused its influence on functional...
first_page Download PDF settings Order Article Reprints Font Type: Arial Georgia Verdana Size: Aa Line Spacing: Column Width: Background: Open AccessAbstract Glycodinameric Hydrogels Based on Chitosan and a Vanillin Isomer † by Manuela Maria IftimeManuela Iftime Scilit Preprints.org Google Scholar View Publications 1, Florentina GeorgescuFlorentina Georgescu 2, Alina NicolescuAlina Nicolescu Luminita MarinLuminita Marin 1,* Florin OanceaFlorin Oancea 3,* 1 "Petru Poni" Institute for...
Betulin is a naturally originating terpenoid, which attracted the attention of researchers due to its bioactive properties, including antitumor activity.