Alexandra Bargan

ORCID: 0000-0002-9433-9595
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Research Areas
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Electrospun Nanofibers in Biomedical Applications
  • Silicone and Siloxane Chemistry
  • biodegradable polymer synthesis and properties
  • Advanced Cellulose Research Studies
  • Hydrogels: synthesis, properties, applications
  • Metal complexes synthesis and properties
  • Metal-Organic Frameworks: Synthesis and Applications
  • Advanced Sensor and Energy Harvesting Materials
  • Conducting polymers and applications
  • Nanocomposite Films for Food Packaging
  • Advanced Polymer Synthesis and Characterization
  • Crystallography and molecular interactions
  • Covalent Organic Framework Applications
  • Advanced Drug Delivery Systems
  • Polymer Nanocomposites and Properties
  • Dental materials and restorations
  • Membrane Separation and Gas Transport
  • Synthesis and properties of polymers
  • Membrane Separation Technologies
  • Crystal structures of chemical compounds
  • Polysaccharides Composition and Applications
  • Marine Biology and Environmental Chemistry
  • Magnetism in coordination complexes

Romanian Academy
2021-2025

Institutul de Chimie Macromoleculară Petru Poni
2015-2024

Grigore T. Popa University of Medicine and Pharmacy
2021-2024

Institute of Macromolecular Chemistry
2014-2023

Biopolymer nanocomposite films were prepared by casting film-forming emulsions based on chitosan/Tween 80/rosehip seed oil and dispersed montmorillonite nanoclay C30B. The effect of composition structural, morphological characteristics and, mechanical, barrier, antimicrobial antioxidant properties was studied. presence rosehip in chitosan led to the formation flexible with improved gas water vapour barrier activity. vitro antibacterial tests against Escherichia coli, Salmonella typhymurium,...

10.3390/ma12030373 article EN Materials 2019-01-25

Topical approaches to dermatophytosis have the advantage of targeted therapy and minimal side effects are patient-friendly. The present study focused on obtaining thin, flexible, transparent bioadhesive polymeric films loaded with terbinafine hydrochloride (TH), in order be administered skin affected by fungal infection. Polymeric based pullulan (P), oxidized (T-OP), sodium carboxymethylcellulose (NaCMC), glycerin were obtained casting evaporation technique, solubility drug was significantly...

10.3390/polym17081004 article EN Polymers 2025-04-08

Recently, the development of new materials with desired characteristics for functional tissue engineering, ensuring architecture and supporting cellular growth, has gained significant attention. Hydrogels, which possess similar properties to natural matrixes, being able repair or replace biological tissues support healing process through proliferation viability, are a challenge when designing scaffolds. This paper provides insights into hydrogel-based polymeric blends (hydroxypropyl...

10.3390/gels8080519 article EN cc-by Gels 2022-08-19

The majority of recent studies have focused on obtaining MRI materials for internal use. However, this study focuses a straightforward method preparing gelatin-based with iron oxide nanoparticles (G-Fe2O3 and G-Fe3O4) external newly obtained must be precisely tuned to match the requirements usage situation because they will in close touch human/animal skin. biocompatible structures formed by gelatin, tannic acid, were investigated using FTIR spectroscopy, SEM-EDAX analysis, contact angle...

10.3390/ma15103479 article EN Materials 2022-05-12

EPDM/hemp fiber composites with loading of 0-20 phr were prepared by the blending technique on a laboratory electrically heated roller mill. Test specimens obtained vulcanization using hydraulic press. The elastomer crosslinking and chemical modification hemp surface achieved radical reaction mechanism initiated di(tert-butylperoxyisopropyl)benzene. influence mechanical properties, gel fraction, swelling ratio crosslink degree was investigated. density rubber-hemp interaction evaluated based...

10.3390/ma15196838 article EN Materials 2022-10-01

The progress achieved in recent years the biomedical field justifies objective evaluation of new techniques and materials obtained by using silver different forms as metallic silver, salts, nanoparticles. Thus, antibacterial, antiviral, antifungal, antioxidant, anti-inflammatory activity nanoparticles (AgNPs) confers to newly characteristics that make them ideal candidates a wide spectrum applications. In present study, use hydroxypropyl methyl cellulose (HPMC) formulation, embedding AgNPs...

10.3390/polym15071625 article EN Polymers 2023-03-24

In recent years, multidrug-resistant bacteria have developed the ability to resist multiple antibiotics, limiting available options for effective treatment. Raising awareness and providing education on appropriate use of as well improving infection control measures in healthcare facilities, are crucial steps address crisis. Further, innovative approaches must be adopted develop novel drug delivery systems using polymeric matrices carriers support efficiently combat such thus promote wound...

10.3390/gels9080655 article EN cc-by Gels 2023-08-14

Electrospinning is a widely used technology for obtaining nanofibers from synthetic and natural polymers. In this study, electrospun mats collagen (C), polyethylene terephthalate (PET) blend of the two (C-PET) were prepared stabilized through cross-linking process. The aim research was to prepare characterize nanofiber structure by Fourier-transform infrared with attenuated total reflectance spectroscopy (FTIR-ATR) in close correlation dynamic vapor sorption (DVS). studies indicated that...

10.3390/ma13183961 article EN Materials 2020-09-07

In this paper, hydroalcoholic solutions of Thymus vulgaris, Salvia officinalis folium, and Hyperici herba were used in combination with poly (vinyl alcohol) the aim developing novel alcohol)-based nanofiber mats loaded phytotherapeutic agents via electrospinning technique. The chemical structure morphology polymeric nanofibers investigated using Fourier Transform Infrared Spectroscopy (FTIR) Scanning Electron Microscopy (SEM). addition extracts to pure polyvinyl alcohol fibers led changes a...

10.3390/nano11123336 article EN cc-by Nanomaterials 2021-12-08

10.1016/j.jmbbm.2023.106002 article EN Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials 2023-06-30

In this paper, the synthesis and characterization of two polycaprolactone-polydimethylsiloxane (PDMS-CL) copolymers with biodegradable properties are reported. A comparative study was carried out using an aminopropyl-terminated polydimethylsiloxane macro-initiator (APDMS) different molecular weights. The (PDMS-CL-1 PDMS-CL-2) were obtained by ring-opening polymerization ɛ-caprolactone APDMS as initiators stannous 2-ethylhexanoate a catalyst. copolymer's structures confirmed Fourier transform...

10.3390/polym15244731 article EN Polymers 2023-12-17

Allantoin and its β-cyclodextrin hydroxypropyl-β-cyclodextrin inclusion complexes 1:1 have been used to prepare carbopol-based mucoadhesive gels. The gelation process occurred by adjustment with glycerol 10% in the presence of triethanolamine. structural features induced allantoin corresponding β-cyclodextrins first investigated infrared spectroscopy highlighting strong interactions within gels network ideal crosslinks for self-healing behavior. hydrophilicity was determination surface...

10.3390/gels8070416 article EN cc-by Gels 2022-07-02

Dental composites, through their structural diversity, represent the biomaterials frequently used in dental reconstructive therapy. The aim of our study was to observe influence different beverage environment conditions on seven types obturation materials with compositions. Our research focused surface modification analysis after immersion beverages; this regard, we EDAX technique correlated energy-dispersive X-ray fluorescence (XRF). pH drinks and that simulated saliva solution were...

10.3390/biomedicines11092571 article EN cc-by Biomedicines 2023-09-19

New Schiff base-type products starting from 1-(3-aminopropyl)silatrane and three derivatives of salicylaldehyde having as substituents 3,5-dichloro- (1), 3-methoxy- (2) 3,5-di-tert-butyl- (3), respectively were obtained isolated with high yields (78–87%) in pure, crystalline forms their structures established by different methods. The molecular electronic transitions the compounds solvents various polarities investigated UV–Vis spectral analysis. Their thermal behavior was studied...

10.1016/j.arabjc.2018.09.001 article EN cc-by-nc-nd Arabian Journal of Chemistry 2018-09-08
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