A5007953899- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Luminescence and Fluorescent Materials
- Nanocomposite Films for Food Packaging
- Hydrogels: synthesis, properties, applications
- Liquid Crystal Research Advancements
- Molecular Sensors and Ion Detection
- Synthesis and properties of polymers
- Electrospun Nanofibers in Biomedical Applications
- Phenothiazines and Benzothiazines Synthesis and Activities
- Surfactants and Colloidal Systems
- Conducting polymers and applications
- Advanced Drug Delivery Systems
- Wound Healing and Treatments
- Organic Electronics and Photovoltaics
- biodegradable polymer synthesis and properties
- Silk-based biomaterials and applications
- Antimicrobial agents and applications
- Crystallography and molecular interactions
- Nanoparticle-Based Drug Delivery
- Photochromic and Fluorescence Chemistry
- Polymer Surface Interaction Studies
- Analytical Chemistry and Sensors
- Supramolecular Self-Assembly in Materials
- Advanced biosensing and bioanalysis techniques
Romanian Academy
2015-2024
Institutul Regional de Oncologie
2024
Institutul de Chimie Macromoleculară Petru Poni
2014-2023
Institute of Macromolecular Chemistry
2014-2023
InterAcademy Partnership
2023
Grigore T. Popa University of Medicine and Pharmacy
2023
National Institute of Research and Development for Biological Sciences
2023
"Ion Ionescu de la Brad" Iasi University of Life Sciences
2021
Czech Academy of Sciences, Institute of Macromolecular Chemistry
2015
Institute for Macromolecular Studies
2007
The imine-bond formation on chitosan backbones occurs with very low yields in aqueous solutions and is significantly improved hydrogels or solid state films. dynamic exchanges of imino-R groups colour transfer can occur at the interfaces between various
The paper reports new hydrogels based on quaternary ammonium salts of chitosan designed as biocidal products. derivative was crosslinked with salicylaldehyde via reversible imine bonds and supramolecular self-assemble to give dynamic which respond environmental stimuli. crosslinking mechanism demonstrated by 1H NMR FTIR spectroscopy, X-ray diffraction polarized light microscopy. hydrogel nature, self-healing thixotropy were proved rheological investigation visual observation, their...
Abstract An investigation of the constitutional adaptive gelation process chitosan/cinnamaldehyde ( C / Cy ) dynagels is reported. These gels generate timely variant macroscopic organization across extended scales. In first stage, imine‐bond formation takes place “in‐water” and generates low‐ordered hydrogels. The progressive imine bonds further induces “ out‐of‐water” increased reactivity within interdigitated hydrophobic self‐assembled layers , with a protecting environmental effect...
Vanillin-chitosan biodynamers have been prepared and structure-morphology correlations revealed the pathway of progressive incorporation aldehyde onto chitosan backbones. Such dynamic biopolymers or biodynamers, generated from reversibly interacting components, offer possibility to address covalent behaviour reversible imine-bond formation/hydrolysis equilibria between vanillin polymeric The reaction takes place with very low conversion in acidic aqueous solutions (7-12%), but imine bond...
Polymer-dispersed liquid crystal (PDLC) systems based on polysulfone as carrying matrix and 4-cyano-4ʹ-pentylbiphenyl (5CB) (LC) were obtained thin transparent films. The PDLC films prepared by solvent- thermally induced phase separation methods, with various compositions in the two components. Information was polarised light optical microscopy, differential scanning calorimetry electron microscopy. composites show well-defined droplets of submicrometric size, around 650 nm for a medium...
Abstract Chitosan is a biopolymer originating from renewable resources, with great properties which make it an attractive candidate for plenty of applications contemporary interest. By manufacturing chitosan into nanofibers using the electrospinning method, its potential amplified due to enhancement active surface and low preparation cost. Many attempts were made aim preparing chitosan-based controlled morphology targeting their use tissue engineering, wound healing, food packaging, drug...
The paper aims at the preparation of chitosan self-healing hydrogels, designed as carriers for local drug delivery by parenteral administration. To this aim, 30 hydrogels were prepared using and pyridoxal 5-phosphate (P5P), active form vitamin B6 precursors, varying ratio glucosamine units aldehyde on one hand water content other hand. driving forces hydrogelation investigated nuclear magnetic resonance (NMR), Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction, polarized light...
Supramolecular hydrogels based on chitosan and monoaldehydes are biomaterials with high potential for a multitude of bioapplications. This is due to the proper choice monoaldehyde that can tune hydrogel properties specific practices. In this conceptual framework, present paper deals investigation as bioabsorbable wound dressing. To aim, was cross-linked 2-formylphenylboronic acid yield antimicrobial activity. FTIR, NMR, POM procedures have characterized from structural supramolecular point...
A series of drug delivery systems were prepared by chitosan hydrogelation with citral in the presence an antineoplastic drug: 5-fluorouracil. The dynamic covalent chemistry imine linkage allowed obtaining supramolecular tridimensional architectures which has been homogenously dispersed. Fourier-transform infrared spectroscopy (FTIR), wide-angle X-ray diffraction (WXRD) and polarized light microscopy (POM) measurements used order to follow encapsulation processes. ability release investigated...