A5044158077- Essential Oils and Antimicrobial Activity
- Allelopathy and phytotoxic interactions
- Phytochemicals and Antioxidant Activities
- Weed Control and Herbicide Applications
- Pharmacological Effects and Assays
- Nuclear Receptors and Signaling
- Phytochemical and Pharmacological Studies
- Computational Drug Discovery Methods
- Dental materials and restorations
- Synthesis and biological activity
- Dental Trauma and Treatments
- Medicinal plant effects and applications
- Insect Pest Control Strategies
- Analytical Methods in Pharmaceuticals
- Oral and Maxillofacial Pathology
- Bioactive Compounds and Antitumor Agents
- Vanadium and Halogenation Chemistry
- dental development and anomalies
- Ethnobotanical and Medicinal Plants Studies
- Heavy Metal Exposure and Toxicity
- 3D Printing in Biomedical Research
- Endodontics and Root Canal Treatments
- Seaweed-derived Bioactive Compounds
- Bone and Dental Protein Studies
- Botanical Research and Chemistry
Grigore T. Popa University of Medicine and Pharmacy
2011-2025
Wound management represents a continuous challenge for health systems worldwide, considering the growing incidence of wound-related comorbidities, such as diabetes, high blood pressure, obesity, and autoimmune diseases. In this context, hydrogels are considered viable options since they mimic skin structure promote autolysis growth factor synthesis. Unfortunately, associated with several drawbacks, low mechanical strength potential toxicity byproducts released after crosslinking reactions....
The growing popularity of electronic cigarettes has raised several public health concerns, including the risks associated with heavy metals exposure via e-liquids and vapors. purpose this study was to determine, using atomic absorption spectrometry, concentrations Pb, Ni, Zn, Co in some commercially available e-liquid samples from Romania immediately after purchase storage clearomizers. Lead zinc were found all investigated before storage. initial Pb ranged 0.13 0.26 mg L-1, while Zn between...
Five cinnamic acid derivatives [cinnamic acid, 2,3-dibromo-3-phenyl-propanoic 2,3-dibromo-3-(3-bromophenyl)-propanoic 2,3-dibromo-3-(4-hydroxy-3-methoxyphenyl)-propanoic and 2,3-dibromo-3-(3-bromo-4-hydroxy-5-methoxyphenyl)-propanoic acid] were found to be active against Staphylococcus aureus ATCC 25923, their minimal bactericidal concentrations determined (100 µg/mL). The first step in assessing toxicological potential was the phytotoxicity genotoxicity evaluation on Triticum aestivum....
Electronic nicotine delivery systems first appeared on the market in 2003 and have been promoted as healthier alternatives to conventional tobacco cigarettes. The rapid evolution of technology for these products generated a wide variety models, electronic cigarettes quickly gained worldwide popularity. However, research regarding effects both short-term long-term exposure revealed potential negative human health, system be affected by smoking devices is oral cavity. This review makes an...
Dermatophyte infections represent an important public health concern, affecting up to 25% of the world's population. Trichophyton rubrum and T. mentagrophytes are predominant dermatophytes in cutaneous infections, with a prevalence accounting for 70% dermatophytoses. Although terbinafine represents preferred treatment, its clinical use is hampered by side effects, drug-drug interactions, emergence resistant isolates. Combination therapy, associating essential oils (EOs), promising strategy...
Pesticide poisoning in pediatric patients is still an important reason for presenting to the emergency department Romania. In this context, present study aims raise awareness of toxicological impact pesticides on human health pediatrics. For purpose, demographic characteristics, clinical assessment, and outcome with acute pesticide admitted toxicology "Saint Mary" Emergency Children's Hospital from Iasi, were analyzed. This retrospective focused laboratory data aged under 18 years diagnosed...
Intensive agriculture has become an indispensable practice because it to meet the needs of increasingly large yields feed population planet.In recent years, tough challenges increase efficiency bioconversion were performed, since conventional system negative impacts on environment, especially health products by low intake in nutrients.In this context, aim study is show effects fertilization measures, which improve quality sweet peppers, rich phenolic compounds, p-coumaric acid (PCA).The...
Background: Recognized widely for its irreversible effects, periodontal disease stands as one of the most prevalent conditions, particularly emphasizing potential permanent damage caused by gingivitis, extending to encompass entirety supportive complex, including connective tissue and alveolar bone. Patients necessitating comprehensive prosthetic treatments require an interdisciplinary approach, involving coordination pre-treatment procedures appropriate strategies. The adoption advanced...
The concept "Molar Incisor Hypomineralization" (MIH) was introduced in 2001 to specify enamel hypomineralization impacting one or more permanent first molars, commonly accompanied by the involvement of incisors. severity carious lesions can be influenced and exacerbated alterations structure dentin. Consequently, MIH syndrome (Molar Hypomineralization syndrome) may pose a significant health concern for pediatric, adolescent, young adult patients, as well their tutors caregivers, both...
The present studies aimed the effects of tyrphostin AG 494 and 1295 on apoptosis mouse pro-B lymphocytes. actual scientific literature lacks such data. Tyrphostin is an inhibitor epidermal growth factor receptor pathways platelet-derived pathways. Our obtained data demonstrated that was less effective in preventing murine cells, triggered by combination Cytoporone B (NR4A1 agonist) Cyclosporine A. In contrast, had a stronger inhibitory effect same when administered for 24 hours. Thus,...
The phytotoxicity of eight dibrominated cinnamic acid derivatives on Phaseolus vulgaris was evaluated.Plant bioassays are usually used for ecotoxicity assessment and in the development new pesticides, but they can also represent simple inexpensive screening tools to identify well-tolerated substances before subjecting them further more complex vivo toxicity tests.Bean seeds were cultivated filter paper impregnated with different concentrations active substance (28.6 μg cm -2 , 57.3 114.6 )...
Physiological/normal tooth mobility may be defined as the slight displacement of clinical crown a tooth, which is allowed by resilience an intact and healthy periodontium, under application moderate force. The factors influencing success longevity dental splinting are type material used for splint, composite resin, number location units included (maxillary or mandibular arch). In periodontology, term 'splint' joining two more teeth into rigid unit through restorations fixed removable...
There is a lack of data in the mainstream literature regarding interactions between gingival fibroblasts, as component local niche, and tumor precursors B-lymphocytes. Although it known that development tumors depends on environment's characteristics. In order to experimentally evaluate apoptosis pro-B type lymphocytes, induced result activation orphan nuclear receptor 4A1 (NR4A1), through Cytosporone B (Csn-B, 10 μM), presence or absence exosomes derived from we administered treatment: 1 μM...