Simon Vlad Luca

ORCID: 0000-0001-8785-249X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Phytochemistry and Biological Activities
  • Essential Oils and Antimicrobial Activity
  • Natural product bioactivities and synthesis
  • Botanical Studies and Applications
  • Chromatography in Natural Products
  • Phytochemistry and Bioactive Compounds
  • Medicinal plant effects and applications
  • Botanical Research and Chemistry
  • Plant chemical constituents analysis
  • Phytochemicals and Antioxidant Activities
  • Plant Toxicity and Pharmacological Properties
  • Phytochemical and Pharmacological Studies
  • Analytical Chemistry and Chromatography
  • Fungal Biology and Applications
  • Curcumin's Biomedical Applications
  • Antioxidant Activity and Oxidative Stress
  • Seaweed-derived Bioactive Compounds
  • Sirtuins and Resveratrol in Medicine
  • Phytochemistry and biological activity of medicinal plants
  • Botany, Ecology, and Taxonomy Studies
  • Cholinesterase and Neurodegenerative Diseases

Technical University of Munich
2019-2024

Grigore T. Popa University of Medicine and Pharmacy
2018-2021

Medical University of Lublin
2018-2020

Medicina
2020

As a continuation of searching for phytoconstituents that act as promising agents antimicrobial therapy, rare coumarins were isolated from fruits Peucedanum luxurians and tested. In first step, the content major compounds in aerial parts P. compared. The results clearly showed with dichloromethane solvent yielded, most cases, higher concentrations almost all analyzed than parts, peucedanin detected abundant compound concentration 4563.94 ± 3.35 mg/100 g. Under this perspective, extract was...

10.3390/molecules23051222 article EN cc-by Molecules 2018-05-20

Abstract Introduction Plant species of Verbascum genus have been intensively investigated in the last decades but most studies focused on evaluation their biological activities; there are only few dealing with chemical characterisation. Objective Detailed investigation qualitative and quantitative composition, antioxidant cytogenotoxic activities a previously non‐studied ( V. ovalifolium Donn ex Sims). Methods Qualitative analysis secondary metabolites was performed by...

10.1002/pca.2788 article EN Phytochemical Analysis 2018-08-28

Abstract BACKGROUND Symphytum (comfrey) genus, particularly officinale , has been empirically used in folk medicine mainly for its potent anti‐inflammatory properties. In an attempt to shed light on the valorization of less known taxa, current study evaluated metabolite profile and antioxidant enzyme inhibitory effects nine species. RESULTS Phenolic acids, flavonoids pyrrolizidine alkaloids were most representative compounds all comfrey samples. Hierarchical cluster analysis revealed that,...

10.1002/jsfa.13279 article EN cc-by-nc Journal of the Science of Food and Agriculture 2024-01-22

Abstract Thymus species are important aromatic, medicinal and culinary plants with a significant economic value. This study evaluated for the first time chemical composition in vitro bioactivities of essential oils ( EO s) from five Moldavian T. vulgaris , T . × citriodorus calcareus ) cultivars ‘Faustini’, ‘Aureus’). The main compounds s were: thymol (55.44% 55.45%, respectively), lavandulol (54.27%), geraniol ‘Aureus’ ‘Faustini’ (60.31% 31.45%, respectively). showed most potent antioxidant...

10.1002/ffj.3490 article EN Flavour and Fragrance Journal 2019-01-31

The aim of this study was to evaluate the impact that 6-O-(3″, 4″-di-O-trans-cinnamoyl)-α- l-rhamnopyranosylcatalpol (Dicinn) and verbascoside (Verb), two compounds simultaneously reported in Verbascum ovalifolium, have on tumor cell viability, apoptosis, cycle kinetics, intracellular reactive oxygen species (ROS) level. At 100 µg/mL 48 hours incubation time, Dicinn Verb produced good cytotoxic effects A549, HT-29, MCF-7 cells. induced cell-cycle arrest at G0 /G1 phase whereas increased...

10.1002/jbt.22443 article EN Journal of Biochemical and Molecular Toxicology 2020-01-07

Abstract In the current study, ethanol extracts of flower, stem, and root parts two endemic Turkish species, e. g ., Haplophyllum sahinii O. Tugay & D. Ulukuş H. vulcanicum Boiss . Heldr were screened against acetylcholinesterase (AChE) butyrylcholinesterase (BChE) associated with Alzheimer's disease as well tyrosinase (TYR) linked to Parkinson's using ELISA microplate assay at 200 μg/mL. Among extracts, highest inhibition was caused by stem extract BChE (IC 50 =64.93±1.38 μg/mL)....

10.1002/cbdv.201900333 article EN Chemistry & Biodiversity 2019-07-31

The separation of cannabinoids from hemp materials is nowadays one the most promising industrial applications liquid-liquid chromatography (LLC). Despite various experimental research efforts to purify cannabinoids, there are currently few works on process modeling. Thus, this study aimed explore a straightforward approach model LLC two extracts with different compositions. feed were simplified mixtures preselected key components (i.e., cannabidiol, tetrahydrocannabinol, cannabigerol, and...

10.1002/jssc.202400239 article EN cc-by-nc Journal of Separation Science 2024-06-01

Abstract With around 34 recognized species, Symphytum genus (comfrey) has a noteworthy position within the Boraginaceae family. Comfrey species have been empirically used since ancient times as wound-healing and skin-regenerating agents in ulcers, wounds, bone fractures, rheumatic complaints. This review aims to provide thorough examination of recent scientific advances challenges genus, covering data published between 2013 2023. It delivers an updated overview taxonomy, ethnopharmacological...

10.1007/s11101-024-09977-1 article EN cc-by Phytochemistry Reviews 2024-07-03
Coming Soon ...