RANKL (receptor activator of nuclear factor kappa-β ligand) and OPG (osteoprotegerin) are two proteins involved in bone remodelling. During the active phase periodontal disease, an imbalance between ratios elements can be noticed. While expression is elevated compared with that OPG, available to bond RANK kappa-β). This study was conducted on 41 patients: 19 generalized aggressive periodontitis, 18 severe chronic 4 healthy subjects. For each patient included, we determined salivary levels...

Periodontitis is one of the most common immune-mediated inflammatory conditions resulting in progressive destruction periodontium. Metalloproteinase-9 (MMP-9), an enzyme that involved degradation gelatin and collagen present gingival crevicular fluid, markedly increased periodontitis. The aim study to evaluate effects periodontal treatment either alone or combination with orthodontic on MMP-9 levels. In this study, 60 individuals were subjected (PD) combined (POD). Both plus treatments...

Inlay-retained dental bridges can be a viable minimally invasive alternative when patients reject the idea of implant therapy or conventional retained full-coverage fixed prostheses, which require more tooth preparation. are indicated in with good oral hygiene, low susceptibility to caries, and minimum coronal height 5 mm. The present study aims evaluate, through finite element method (FEM), stability these types stresses on supporting teeth, under action masticatory forces. analysis...

The growing popularity of electronic cigarettes has raised several public health concerns, including the risks associated with heavy metals exposure via e-liquids and vapors. purpose this study was to determine, using atomic absorption spectrometry, concentrations Pb, Ni, Zn, Co in some commercially available e-liquid samples from Romania immediately after purchase storage clearomizers. Lead zinc were found all investigated before storage. initial Pb ranged 0.13 0.26 mg L-1, while Zn between...

Background and Objectives: The surface condition of the materials that are used for temporary prostheses influences their microbial colonization, with a direct impact on oral tissues. This study aims at comparative analysis three types resins bridges using conventional digital technologies. attention was focused characteristics mechanical strength these materials. Materials Methods: assessed distinct both before after polishing- heat-curing resin Superpont C + B (SpofaDental, Jicin, Czech...

Chronic periodontitis is a disease caused by several factors; therefore, it can be called multifactorial disease. Such risk factors include smoking, diabetes, genetics, depression, and stress. Depression one of the chronic conditions with highest prevalence worldwide. There evidence to support association between psychological disorders physiological behavioral precursors caries periodontal disease, suggesting that such connection may exist. Antidepressant anxiolytic medication have been...

Electronic nicotine delivery systems first appeared on the market in 2003 and have been promoted as healthier alternatives to conventional tobacco cigarettes. The rapid evolution of technology for these products generated a wide variety models, electronic cigarettes quickly gained worldwide popularity. However, research regarding effects both short-term long-term exposure revealed potential negative human health, system be affected by smoking devices is oral cavity. This review makes an...

Background and Objectives: Acrylic resins remain the materials of choice for removable prosthesis due to their indisputable qualities. The continuous evolution in field dental offers practitioners today a multitude therapeutic options. With development digital technologies, including both subtractive additive methods, workflow has been considerably reduced precision prosthetic devices increased. superiority prostheses made by methods compared conventional is much debated literature. Our...

Neoplasia occurs as a result of genetic mutations. Research evaluating the association between gene mutations and skin cancer is limited has produced inconsistent results. There are no established guidelines for screening at molecular level. It should also be noted that combinations some may play role in tumors’ biology immune response. three major types cancer, originality this study comes from its approach each them.

The aim of this study was to evaluate the differences in RANKL levels crevicular fluid (GCF) patients with chronic periodontitis, or without occlusal trauma. group consisted 40 from whom 72 samples were collected. analyzed by ELISA. We noticed significantly higher for (occlusive trauma patients) than systemic healthy (p = 8.008). Research has shown that secondary associated periodontal disease is characterized This partially clarifies molecular mechanisms underlie more severe tissue destruction

Purpose. Craniofacial morphology is usualy described by the head (cephalic index) and face form (prosopic index). The aim of this study was to establish existence correlations between cranial facial types dento-maxillary anomalies. Material Methods. Data were collected from two groups patients (a control group 42 without dental anomalies a test 76 with anomalies) both sexes age range 11-16 years. Results. Both in groups, 50% classified mesocephalic type mesoprosopic type. Conclusions. Groups...

Periodontal disease is progressive and episodic in nature, with tissue destruction resulting from the host response to bacterial antigens irritants.This study aimed evaluate genotype of a certain group pathogen agents. In order this we used total 45 patients PAG included epidemiological analyzes mean age 34.7 Four samples were collected subgingival plaque each patient, 224 dental plaques investigated. All tested for presence Tannerella forsythensis, Porphyromonas gingivalis Treponema...

The present study aimed to analyze local and regional changes in regards odontogenic sinusitis subjects with endo‑periodontal lesions diabetes mellitus investigate the effect on level of glycemic control (glycated hemoglobin) that could be generated by adjunctive therapy subantimicrobial doses doxycycline. This was performed 51 who were divided into two therapeutic groups: 31 patients (the group) underwent conventional doxycycline 20 followed only group). Patients endodontic periodontal...

Objectives: Soft and hard tissue breakdown was histologically radiologically assessed around implants with alternate, consecutively placed ligatures on the same edentulous dog hemimandible. The influence of ligatured (LI) adjacent non-ligatured (NLI, as a possible naturally induced peri-implantitis) also evaluated. Material Methods: Three months after tooth extraction, five dental were in Two abutment placement, subsequently two apart alternate implants, while both intermediate left without...

The aim of this study is to evaluate the periodontal status parameters in patients treated with chemotherapy, or without adjuvant bevacizumab, establish a correlation between type administered chemotherapy and status.

Chemotherapy often presents side effects, including oral adverse effects that may interfere with the completion of oncology treatment, threatening outcome treatment and significantly affecting quality life patient. The aim present study was to evaluate two antiseptic, antimicrobial antifungal substances be used in order achieve improved hygiene lower prevalence during chemotherapy. Patients were randomly divided into three groups: Placebo, rinse cetrimide mouth coating a pharmacy‑made...

Because cyancobalamin deficiency is commonly treated with parenteral adminstration, the present study aims to make a comparison between effectiveness of vitamin B12 treatment and local achieved by complete dentures improved crosslinked polymerization using as template (cyanocobalamin).