Răzvan Drăgoi

ORCID: 0000-0002-3991-7583
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Research Areas
  • Rheumatoid Arthritis Research and Therapies
  • Autoimmune and Inflammatory Disorders Research
  • Spondyloarthritis Studies and Treatments
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Systemic Sclerosis and Related Diseases
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Pharmaceutical studies and practices
  • Cerebral Palsy and Movement Disorders
  • Chronic Disease Management Strategies
  • Antibiotics Pharmacokinetics and Efficacy
  • Musculoskeletal pain and rehabilitation
  • Tannin, Tannase and Anticancer Activities
  • Anesthesia and Sedative Agents
  • Psoriasis: Treatment and Pathogenesis
  • Salivary Gland Disorders and Functions
  • Hip and Femur Fractures
  • Musculoskeletal Disorders and Rehabilitation
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Natural product bioactivities and synthesis
  • Adolescent and Pediatric Healthcare
  • Pregnancy and Medication Impact
  • Galectins and Cancer Biology
  • Liver Disease Diagnosis and Treatment
  • Plant Genetic and Mutation Studies

Victor Babeș University of Medicine and Pharmacy Timișoara
2014-2024

Medical University of Vienna
2013

In order to target educational needs of patients more effectively, an Austrian-German assessment tool (OENAT) was developed, the with rheumatoid arthritis (RA), psoriatic (PsA) and hand osteoarthritis (HOA) were described relationships between needs, gender, disease activity function explored. The English ENAT adapted into using Beaton's cross-cultural adaptation process. Internal construct validity assessed by Rasch analysis. Educational across diagnostic groups subgroups summarized...

10.1186/ar4339 article EN cc-by Arthritis Research & Therapy 2013-01-01

To evaluate the impact of inspiratory muscle training on aerobic capacity and pulmonary function in patients with ankylosing spondylitis.Randomized controlled study.Rheumatic Rehabilitation Centre.A total 54 spondylitis patients, all males, were randomized to a conventional exercise associated an group, or group.Group 1 (27 patients) performed eight weeks (supervised weekly group sessions followed by home-based programme) sessions. Group 2 received only.Resting (forced vital - FVC, forced...

10.1177/0269215515578292 article EN Clinical Rehabilitation 2015-03-25

Objective To analyse how non-adherence to prescribed treatments might be prevented, screened, assessed and managed in people with rheumatic musculoskeletal diseases (RMDs). Methods An overview of systematic reviews (SR) was performed four bibliographic databases. Research questions focused on: (1) effective interventions or strategies, (2) associated factors, (3) impact shared decision making communication, (4) practical things prevent non-adherence, (5) effect on outcome, (6) screening...

10.1136/rmdopen-2020-001432 article EN cc-by-nc RMD Open 2020-11-01

Introduction Occupational balance is an important and widely used concept in occupational therapy science. There is, however, not one unified definition use, but several different ones, thus instruments that measure the research studies are diverse as well. Consequently, it unclear how definitions correspond. The purpose of this study was to examine coverage by instruments. Method Within a mixed-methods design we conducted qualitative quantitative content analysis items existing Definitions...

10.1177/0308022614561235 article EN British Journal of Occupational Therapy 2015-01-01

Personal factors (PFs) are internal that determine functioning and the individuals' experience of disability. Their coverage by patient-reported outcome measures (PROMs) has not been examined in rheumatoid arthritis (RA) so far. The aims this study were to identify PFs important life stories people with RA their PROMs used RA.The qualitative data was explored PFs. Additionally a systematic literature search conducted find RA. items linked components, domains categories International...

10.1186/s12955-015-0214-8 article EN cc-by Health and Quality of Life Outcomes 2015-02-24

Despite the reported benefits of intravenous iron therapy (IVIT) for correcting deficiency anemia (IDA) before any major surgery and evidence thereof, perioperative allogenic blood transfusion (ABT) practice is still considered as only viable option by some clinicians worldwide. As ABT increases likelihood infections, cardiac complications, longer hospital stays mortality among patients, should be reserved critical cases (Hb level < 7 g/dl). Timely studies replenishment (oral/IV) prospective...

10.1038/s41598-020-75535-2 article EN cc-by Scientific Reports 2020-10-27

The use of tobacco products is a major global public health issue, as it the leading cause preventable death worldwide. In addition, nicotine (NIC) key component electronic and conventional cigarettes. Although nicotine's addictive potential well known, its effects are not entirely understood. Thus, main objective present study was to evaluate toxicological profile both in vitro, at level three healthy cell lines, ovo, chorioallantoic membrane. Five different concentrations were used...

10.3390/ijerph19148881 article EN International Journal of Environmental Research and Public Health 2022-07-21

Objective To establish European League Against Rheumatism (EULAR) points to consider for non-physician health professionals prevent and manage fragility fractures in adults 50 years or older. Methods Points were developed accordance with EULAR standard operating procedures EULAR-endorsed recommendations, led by an international multidisciplinary task force, including patient research partners different from 10 countries. Level of evidence strength recommendation determined each point...

10.1136/annrheumdis-2020-216931 article EN cc-by-nc Annals of the Rheumatic Diseases 2020-04-24

Recent scientific evidence suggests a link between epigenetic changes (DNA methylation) and tumorigenesis. Moreover, potential carcinogenic mechanism of cadmium was associated with in DNA methylation. In this study we investigated the impact CdCl<sub>2</sub> CuSO<sub>4</sub> aqueous solutions on methylation HT‑29 cells by quantifying methyltransferase (DNMT1, DNMT3A DNMT3B) mRNA expression. Furthermore, also studied cytotoxic anti‑migratory these substances. The results showed dose‑dependent...

10.3892/etm.2020.9532 article EN Experimental and Therapeutic Medicine 2020-11-26

Objective: To identify a spectrum of perspectives on functioning and health patients with primary Sjögren's syndrome (pSS) from the five European countries in order to reveal commonalities insights their experiences. Methods: A multicenter focus group study pSS about was performed. Focus groups were chaired by trained moderators based an interview guide, audiotaped, transcribed. After conducting meaning condensation analysis each group, we subsequently combined extracted concepts country...

10.3389/fmed.2021.770422 article EN cc-by Frontiers in Medicine 2021-11-18

Objectives: Soft and hard tissue breakdown was histologically radiologically assessed around implants with alternate, consecutively placed ligatures on the same edentulous dog hemimandible. The influence of ligatured (LI) adjacent non-ligatured (NLI, as a possible naturally induced peri-implantitis) also evaluated. Material Methods: Three months after tooth extraction, five dental were in Two abutment placement, subsequently two apart alternate implants, while both intermediate left without...

10.3390/jcm11206188 article EN Journal of Clinical Medicine 2022-10-20

Magnetoliposomes were placed into the biomedical spotlight due to their unique structure, preserving also magnetic features valuable for applications. The present study provides a preliminary evidence of cytotoxicity induced by betulinic acid-loaded magnetoliposomes (BA-Fe3O4@Lip) on two melanoma cell lines - A375 and B164A5 cells one healthy line mice epidermis JB6 Cl 41-5a cells, augmented references potential BA-Fe3O4@Lip showed significant lines, compared with blank liposomal structures....

10.37358/rc.19.9.7552 article EN cc-by Revista de Chimie 2019-10-15

Low back pain is one of the major public health problems, with approximately 1 in 3 adults experiencing an episode low during their lifetime. The aim this study was to evaluate effect on and physical function a therapeutic protocol including analgesic electrotherapy, lumbar deconstrictor manual therapy kinetic superinductive magnetic field therapy. Patients were divided into two groups 20 respectively. Group treated conventional protocol, while second group received adition Pain assessed by...

10.12680/balneo.2024.745 article EN cc-by-nc-nd Balneo and PRM Research Journal 2024-12-22

The field of metal nanotechnology continues to draw the attention researchers from different areas due outstanding properties nanoparticles. main aims this research were obtain and study two types gold nanoparticles; obtaining pathways (the chemical synthesis biosynthesis based on an aqueous extract lemon balm) involved in research. chemically synthesized nanoparticles loaded with lupeol. After a preliminary physico-chemical characterization, compounds obtained tested order evaluate effects...

10.37358/rc.20.5.8137 article EN cc-by Revista de Chimie 2020-05-29

Background Ongoing education of health professionals in rheumatology (HPR) is critical for high-quality care. An essential factor readiness and a high quality educational offerings. We explored which factors contributed to investigated currently offered postgraduate education, including the European Alliance Associations Rheumatology (EULAR) Methods participants developed an online questionnaire, translated it into 24 languages distributed 30 countries. used natural language processing...

10.1136/rmdopen-2023-003120 article EN cc-by-nc RMD Open 2023-05-01

<h3>Background</h3> Pulmonary involvement in AS patients varies depending on the diagnostic method applied, its frequency beeing reported to be between 20% and 57% using spirometry, 40% 80% studies which high resolution computed tomography was applied. Patients with have reduced pulmonary muscle strength endurance. <h3>Objectives</h3> To evaluate impact of inspiratory training (IMT) aerobic capacity function AS. <h3>Methods</h3> Fifty-four (mean age: 47.8±6.8 years old, all males) were...

10.1136/annrheumdis-2015-eular.6228 article EN Annals of the Rheumatic Diseases 2015-06-01

<h3>Background</h3> Targeted education is likely to enable people with arthritis manage their disease and maintain quality of life. Educational needs assessment tool (ENAT) was developed help practitioners assess relevant priority educational arthritis. <h3>Objectives</h3> To use the Austrian-German (OENAT) test following hypotheses:(i)educational for vary age, gender, duration educationa background (ii)educational are related activity in RA PsA (iii)educational physical function PsA....

10.1136/annrheumdis-2013-eular.1087 article EN Annals of the Rheumatic Diseases 2013-06-01

Neuromuscular electrical stimulation (NMES) is useful for muscle strengthening and motor restoration of stroke patients. Using a portable ultrasound instrument, we developed an M-mode imaging protocol to visualize contractions elicited by NMES in the quadriceps group. To quantify activation, performed digital image processing based on Teager–Kaiser energy operator. The proposed method was applied 35 voluntary patients (18 women 17 men), 63.8 ± 14.1 years body mass index (BMI) 30.2 6.70 kg/m2...

10.3390/diagnostics11010065 article EN cc-by Diagnostics 2021-01-03

<h3>Background</h3> Primary Sjögren's syndrome (pSS) is one of the most common systemic autoimmune disorders and leads to an impaired health related quality life. However, treatment mainly focuses on management physical manifestations. Little known about lived experiences people with pSS, including impact people's life, functioning their social relationships. <h3>Objectives</h3> To explore perspectives pSS from different European countries various cultural backgrounds in order achieve a...

10.1136/annrheumdis-2018-eular.4699 article EN Annals of the Rheumatic Diseases 2018-06-01

Abstract With time, medical and pharmaceutical research has advanced significantly. However, one of the major issues is how to administer active substance. Among these, it counts over- or under-dosage substance, low re­sponse treatment, increased clinical risk patient. An innovative method able avoid these obstacles represented by controlled release systems for substances. The interest came with allowing encapsulation in antibiotic matrices, local anesthetics, protein other Moreover, a...

10.2478/cejcr-2018-0011 article EN Central European Journal of Clinical Research 2018-12-01

Armoracia rusticana � horseradish is a well-known vegetable used from ancient times and consumed nowadays more for its taste than pharmacological properties, even though it proved to be good agent in fighting several health problems. This study focuses on comparative assessment of hydro-alcoholic extracts, obtained roots sprouts, respectively, mainly evaluating the antioxidant activity but also potential cytotoxic effect. The DPPH evaluation revealed that extracts made or sprouts exhibit...

10.37358/rc.20.5.8128 article EN cc-by Revista de Chimie 2020-05-29

Background: Non-adherence to medication and non-pharmacological interventions precludes reaching an optimal outcome. 30 80% of patients with rheumatic musculoskeletal diseases (RMDs) do not adhere their recommended treatment regimens. Objectives: The objective this EULAR task force was establish recommendations/points consider (PtC) for the detection, assessment management non-adherence in people RMDs. Methods: A (TF) established, standardised operating procedures development PtCs were...

10.1136/annrheumdis-2020-eular.787 article EN Annals of the Rheumatic Diseases 2020-06-01
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