A5089677576- 3D Printing in Biomedical Research
- Nuclear physics research studies
- Cellular Mechanics and Interactions
- Additive Manufacturing and 3D Printing Technologies
- Nuclear Physics and Applications
- Quantum Chromodynamics and Particle Interactions
- Tissue Engineering and Regenerative Medicine
- Particle physics theoretical and experimental studies
- Body Composition Measurement Techniques
- Bone Tissue Engineering Materials
- Innovative Microfluidic and Catalytic Techniques Innovation
- Modular Robots and Swarm Intelligence
- Electrospun Nanofibers in Biomedical Applications
- Thermoregulation and physiological responses
- High-Energy Particle Collisions Research
- Magnetic and Electromagnetic Effects
- Dental materials and restorations
- Mathematical Biology Tumor Growth
- Astro and Planetary Science
- Anatomy and Medical Technology
- Astronomical and nuclear sciences
- Sports Performance and Training
- Protein Structure and Dynamics
- Lattice Boltzmann Simulation Studies
- Infrared Thermography in Medicine
Victor Babeș University of Medicine and Pharmacy Timișoara
2016-2025
University of Missouri
2012-2025
Institute of Space Science - INFLPR Subsidiary
2016-2020
Aliah University
2016
Institute of Space Sciences
2016
West University of Timişoara
1997-2007
Medical University of South Carolina
2004
Freie Universität Berlin
1993
Self-assembly is a fundamental process that drives structural organization in both inanimate and living systems. It the course of self-assembly cells tissues early development organism its parts eventually acquire their final shape. Even though developmental patterning through under strict genetic control it clear ultimately physical mechanisms bring about complex structures. Here we show, experimentally by using computer simulations, how tissue liquidity can be used to build constructs...
The Compact Linear Collider (CLIC) is an option for a future $${\mathrm{e}^{+}}{\mathrm{e}^{-}} $$ collider operating at centre-of-mass energies up to $$3\,\text {TeV} , providing sensitivity wide range of new physics phenomena and precision measurements the energy frontier. This paper first comprehensive presentation Higgs reach CLIC three stages: $$\sqrt{s} = 350\,\text {GeV} 1.4 . initial stage operation allows study boson production in Higgsstrahlung ( \rightarrow {\mathrm{Z}}...
We evaluated the self-assembly properties of uniluminal vascular spheroids having outer layers smooth muscle cells and a contiguous inner layer endothelial lining central lumen. showed that while pairs suspended in culture medium fused to form larger diameter spheroidal structure, collagen hydrogels formed elongated structures. These findings highlight potential use as modules engineer blood vessels. also demonstrate spheroid fusion conforms models describing coalescence liquid drops....
Bioprinting is an evolving tissue engineering technology. It utilizes computer controlled three-dimensional printers for rapid and high-precision construction of biological structures. We employed discrete continuous bioprinting to build constructs. In the former case bioink particles - spherical cell aggregates composed many thousands cells are delivered one by into biocompatible scaffolds, biopaper. Structure formation takes place subsequent fusion due their liquid-like self-assembly...
Computer modeling of multicellular systems has been a valuable tool for interpreting and guiding in vitro experiments relevant to embryonic morphogenesis, tumor growth, angiogenesis and, lately, structure formation following the printing cell aggregates as bioink particles. Here we formulate two computer simulation methods: (1) kinetic Monte Carlo (KMC) (2) cellular particle dynamics (CPD) method, which are capable describing predicting shape evolution time three-dimensional during their...
Organs form during morphogenesis, the process that gives rise to specialized biological structures of specific shape and function in early embryonic development. Morphogenesis is under strict genetic control, but evolution itself a physical process. Here we report results experimental modeling biophysical studies on vitro structure formation. Experimentally, by controlling interaction between cells their embedding matrices, were able build living definite geometry. The experimentally...
Three-dimensional (3D) bioprinting is the use of computer-controlled transfer processes for assembling bioinks (cell clusters or materials loaded with cells) into structures prescribed 3D organization. The correct parameters ensure a fast and accurate bioink deposition without exposing cells to harsh conditions. This study seeks optimize pneumatic extrusion-based based on hydrogel flow rate extrusion speed measurements. We measured through cylindrical nozzle used non-Newtonian hydrodynamics...
Aggregates of living cells (i.e. model tissue fragments) under appropriate conditions fuse like liquid drops. According to Steinberg's differential adhesion hypothesis (DAH), this may be understood by assuming that are motile and tissues made such possess an effective surface tension. Here we show based on these properties three‐dimensional cellular structures prescribed shape can constructed a novel method: cell aggregate printing. Spherical aggregates similar size with known adhesive were...
The notion of apparent tissue surface tension offered a systematic way to interpret certain morphogenetic processes in early development. It also allowed deducing quantitative information on cellular and molecular parameters that is otherwise difficult obtain. To accurately determine such tensions we combined novel experiments with the exact solution Laplace equation for profile liquid drop under employed experimental conditions used evaluate data collected tissues. Our results confirm...
The tumor microenvironment (TME) influences cancer progression. Therefore, engineered TME models are being developed for fundamental research and anti-cancer drug screening. This paper reports the biofabrication of 3D-printed avascular structures that recapitulate several features TME. is represented by a hydrogel droplet uniformly loaded with breast cells (106 cells/mL); it embedded in same type containing primary cells—tumor-associated fibroblasts isolated from peritumoral environment...
A gas of electrons confined to a plane is examined in both the relativistic and nonrelativistic case. Using (0+1)-dimensional effective theory, remarkably simple method proposed calculate spin density induced by an uniform magnetic background field. The physical properties possible fluxon excitations are determined. It found that while case they can be considered as half-fermions (semions) carry half fermion charge fermion, should thought fermions, having fermion.
As a theoretical framework for understanding the self-assembly of living cells into tissues, Steinberg proposed differential adhesion hypothesis (DAH) according to which specific cell type possesses apparatus that combined with motility leads assemblies various types in lowest adhesive energy state. Experimental and efforts four decades turned DAH fundamental principle developmental biology has been validated both vitro vivo. Based on computational models sorting, we have developed DAH-based...
Dental implant insertion requires the preparation of bed via surgical drilling. During this stage, irrigation is essential to avoid thermal damage surrounding bone. Surgical guides enhance accuracy site preparation, but they mask drilling site, hampering coolant delivery. A variety designs are aimed at improving access target site. Using standard dental simulation software, paper presents an in-house design and 3D printing workflow for building that incorporate a channel directed toward...
Abstract Background/Objectives Several studies have addressed the validity of ultrasound (US) for body composition assessment, but few evaluated its reliability. This study aimed to determine reliability percent fat (%BF) estimates using A-mode US in a heterogeneous sample. Subjects/Methods A group 144 healthy adults (81 men and 63 women), 30.4 (10.1) years (mean (SD)), BMI 24.6 (4.7) kg/m 2 , completed 6 consecutive measurements subcutaneous layer thickness at 8 anatomical sites. The were...