A5072308029- Rheumatoid Arthritis Research and Therapies
- Musculoskeletal synovial abnormalities and treatments
- Orthopedic Surgery and Rehabilitation
- Hip and Femur Fractures
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Bone health and osteoporosis research
- Chronic Disease Management Strategies
- Sepsis Diagnosis and Treatment
- Acute Myocardial Infarction Research
- Healthcare cost, quality, practices
- Inflammatory Bowel Disease
- Orthopedic Infections and Treatments
- Systemic Lupus Erythematosus Research
- Biomarkers in Disease Mechanisms
- Inflammation biomarkers and pathways
- Bone and Joint Diseases
- Viral Infections and Immunology Research
- Cardiovascular Issues in Pregnancy
- S100 Proteins and Annexins
Aarhus University Hospital
2015-2024
Aarhus University
2018-2020
BackgroundPatients with atherosclerotic plaques containing high-risk features have an increased likelihood of events and a worse prognosis. Whether levels Troponin I (TnI) C-reactive protein (CRP) are associated the presence coronary (HRP) is not well described. We assessed association between 1) TnI 2) CRP quantified plaque burden, luminal diameter stenosis, HRP in patients low/intermediate pre-test probability obstructive artery disease (CAD) referred for computed tomography angiography...
Objective To establish European League Against Rheumatism (EULAR) points to consider for non-physician health professionals prevent and manage fragility fractures in adults 50 years or older. Methods Points were developed accordance with EULAR standard operating procedures EULAR-endorsed recommendations, led by an international multidisciplinary task force, including patient research partners different from 10 countries. Level of evidence strength recommendation determined each point...
To investigate whether high-resolution peripheral quantitative CT (HR-pQCT) of two metacarpophalangeal (MCP) joints can more accurately classify patients as having erosive RA compared with conventional radiography (CR) 44 in the hands, wrists and feet.In this single-centre cross-sectional study, established (disease duration ≥5 years) were investigated by HR-pQCT CR. The second third MCP dominant hand assessed for erosions HR-pQCT. CR feet scored according to Sharp-van der Heijde (SHS)...
As an activation product of neutrophil granulocytes, calprotectin has been widely used in fecal samples for diagnosis and monitoring patients with inflammatory bowel disease. However, sample collection is cumbersome, pre-analytical sources error are plentiful. Therefore, plasma being investigated as a promising new biomarker. To utilize any biomarker, factors such stability susceptibility to interference from hemolysis must be established. We present precision estimates, results well study...
Plasma calprotectin is a promising new biomarker of inflammatory activity and has been found to correlate well with clinical endoscopic in children adolescents bowel disease. A pediatric reference interval for plasma not established the Phadia 250 EliA™ Calprotectin fluoroenzyme immunoassay. In studies regarding pre-analytical properties, excellent precision stability was found. However, sensitivity hemolysis demonstrated. We identified blood samples from apparently healthy who were referred...
Abstract Aim Bone erosions are the hallmark of rheumatoid arthritis (RA). High‐resolution peripheral quantitative computed tomography (HR‐pQCT) enables 3‐dimensional visualization arthritic bone at a high resolution. However, degree erosive disease could influence reliability HR‐pQCT evaluation. We aim to assess intra‐ and inter‐reader variability identification in metacarpophalangeal (MCP) joints using healthy controls patients with RA, stratified according van der Heijde‐modified Sharp...
Objective To compare in images, obtained by high-resolution peripheral quantitative computed tomography (HR-pQCT) and conventional radiography (CR) of the second third metacarpophalangeal (MCP) joints, minimal erosive cortical break needed to differentiate between pathological physiological breaks. Methods In this single-center cross-sectional study, patients with established rheumatoid arthritis (disease duration ≥ 5 yrs) had their MCP joints dominant hand investigated HR-pQCT CR. Empirical...
ABSTRACT Background Patients with atherosclerotic plaques containing high-risk features have an increased likelihood of events and a worse prognosis. Whether levels Troponin I (TnI) C-reactive protein (CRP) are associated the presence coronary (HRP) is not well described. We assessed association between 1) TnI 2) CRP quantified plaque burden, luminal diameter stenosis, HRP in patients low/intermediate pre-test probability obstructive artery disease (CAD) referred for computed tomography...