A5062589508- Veterinary Oncology Research
- Virus-based gene therapy research
- Animal Virus Infections Studies
- Wound Healing and Treatments
- Cancer Research and Treatments
- Protease and Inhibitor Mechanisms
- Electrospun Nanofibers in Biomedical Applications
- Endodontics and Root Canal Treatments
- Silk-based biomaterials and applications
- Periodontal Regeneration and Treatments
- Sarcoma Diagnosis and Treatment
- Peptidase Inhibition and Analysis
- Magnesium Alloys: Properties and Applications
- Hydrogen Storage and Materials
- Cardiovascular Conditions and Treatments
- Bone Tissue Engineering Materials
- Virology and Viral Diseases
- Viral gastroenteritis research and epidemiology
- Parasite Biology and Host Interactions
- Diet and metabolism studies
- Dental Implant Techniques and Outcomes
- Genetic factors in colorectal cancer
- Plasma Applications and Diagnostics
- Zebrafish Biomedical Research Applications
- Reconstructive Surgery and Microvascular Techniques
"Ion Ionescu de la Brad" Iasi University of Life Sciences
2014-2024
University of Life Sciences in Lublin
2024
Institut des Sciences et Technologies Moléculaires d'Angers
2020
Université d'Angers
2020
Universitatea Națională de Știință și Tehnologie Politehnica București
2020
Romanian Academy
2020
Donghua University
2020
Laboratoire de Chimie
2020
Spitalul Clinic C.F. Iasi
2015
University of Agronomic Sciences and Veterinary Medicine of Bucharest
2013
Perinatal parvoviral infection in puppies leads to necrotizing myocarditis, resulting either high mortality or gradual heart damage. We believe that canine parvovirus 2 (CPV-2) myocardial is not being fully recognized as a cause of cardiac injury, and fibrosis repair young dogs, despite the significant reduction epidemic myocarditis due extensive vaccination. This study analyzed formalin-fixed, paraffin-embedded tissues obtained from 40 cases aged less than two years, spanning period 2019...
Cerium oxide nanoparticles present the mimetic activity of superoxide dismutase, being able to inactivate excess reactive oxygen species (ROS) correlated with a large number pathologies, such as stents restenosis and occurrence genetic mutations that can cause cancer. This study presents synthesis biological characterisation nanoconjugates based on iron interconnected cerium conjugates.The magnetite-nanoceria has been done in several stages, where key process is coating polyethyleneimine its...
Non-thermal plasma activated water (PAW) has recently emerged as a powerful antimicrobial agent. Despite numerous potential bio-medical applications, studies concerning toxicity in live animals, especially after long-term exposure, are scarce. Our study aimed to assess the effects of watering with PAW on health CD1 mice. was prepared from distilled GlidArc reactor according previously published protocol. The pH 2.78. mice received (experimental group) or tap (control daily for 90 days sole...
Amoxicillin used in early childhood may be associated with enamel hypomineralization. Our aim was to assess disturbances of amelogenesis mice lower incisors induced by chronic administration amoxicillin/clavulanic acid (AMC). Twenty-eight C57BL/6 male mice, similar age, randomly divided into a control and 3 treatment groups (n = 7) received subcutaneous injection, once per day, for 60 days: 50, 100, 150 mg/kg BW AMC. Scanning electron microscopy/energy dispersive X-ray spectroscopy analysis...
Morphological investigations were conducted on four bodies of dogs who died due to severe clinical symptoms following a massive invasion cardiac and pulmonary Dirofilaria. The subjects monitored clinically diagnosed serologically positive for the Heartworm disease. necropsy examination cardiovascular system (right ventricle artery) revealed presence 25 adult parasites in one dog with length ranging between 8 33cm. Macroscopically, lesions consistently observed represented by right...
The study presents the preparation and characterization of new scaffolds based on bacterial cellulose keratin hydrogel which were seeded with adipose stem cells. was obtained by developing an Acetobacter xylinum culture visualized using SEM (scanning electron microscopy) elementally determined through EDAX (dispersive X-ray analysis) tests. Keratin species (β–keratose γ-keratose) extracted hydrolytic degradation from non-dyed human hair. SEM, conductometric titration tests performed for...
The compatibility of wood from mountain pine beetle (Dendroctonus ponderosa) killed lodgepole (Pinus contorta var. latifolia) with Portland cement was investigated based on time-since-death as a quantitative estimator, and the presence blue-stained sapwood, brown rot, or white rot qualitative indicators. exothermic behavior hydration, maximum heat rate, time to reach this maximum, total released within 3.5-24 h interval were used for defining new wood-cement index (CX). CX developed...
ABSTRACT Investigations of four roe deer corpses were carried out from May until October 2014, in the Veterinary Forensic Laboratory and Parasitic Diseases Clinic, Iasi Faculty Medicine. The harvested by shooting during trophy hunting season. clinical examination shot specimens revealed presence a highly consistent number extremely mobile apterous insects, spread on face, head, neck, lateral body parts, abdominal regions, inguinal, perianal and, finally, all over body. presented weakening,...
The toxicity of viologens can be significantly reduced by including them in tight [2]rotaxane structures alongside β-cyclodextrin, thus turning into candidates pharmaceutical interest. Here, we report a synthesis pathway for benign viologen, capping small β-cyclodextrin-caged molecule, the 4,4'-bipyridine, with minimal-length presynthesized axle-stopper segments propyl-3-pentamethyldisiloxane type. After 90 min from oral administration to laboratory mice, product concentration bloodstream...
Introduction Bovine papillomaviruses −1/−2 (BPVs) are small non-enveloped double-stranded DNA viruses able to infect the skin of bovids and equids, causing development neoplastic lesions such as bovine cutaneous fibropapillomas equine sarcoid. Matrix metalloproteinases (MMPs) a group zinc-dependent endopeptidases that degrade basal membrane extracellular matrix, whose function is essential in physiological processes tissue remodeling wound healing. MMPs activity finely regulated by balancing...
The aim of this study was to investigate the effect insulin and strontium ranelate treatment on guided bone regeneration in diabetic rats. This carried out 30 adult Wistar rats with an average weight 250-300 grams. animals underwent a unilateral osteotomy left proximal tibia followed by augmentation collagenized porcine xenografts (Osteobiol� mp3, Tecnoss Dental s.r.l., Torino, Italy) then were randomized into five groups: healthy (H), diabetes (D), insuline (DI), (DS) (DIS)....
Digestive parasitoses negatively affect the goat's health, gain weight of kids, efficiency food conversion, fertility, and productivity, causing important economic losses. This investigation was carried out on a group goats, Carpathian breed, in hill area Tg. Frumos-Iași, to specify etiology acute digestive syndrome, triggered towards end pasturing season, young goats. In this context, four sick animals, aged 6-8 months, were slaughtered. Morphological, pathological, parasitological...
The retromolar-oropharynx junction cancer is a rare malignancy situated at the border between oral cavity and oropharynx.There an important number of factors involved in ethiology, pathogenesis evolution patients with this kind lesions.We performed prospective study involving 50 type cancer, hospitalized 2013-2015 Otorhinolaryngology Maxillofacial Departments "Sf.Spiridon" Emergency Hospital, Iasi, Romania, to identify environmental biologic that may be damaged tissues.The purpose our...
To examine the effect of high dose vitamin D3 treatment on visceral adipose tissue, we used D deficient male Wistar rats (18 months old) as a model sarcopenia. The aging process is not only responsive for losing muscle mass but also redistribution lipid resulting in altered fatty acid storage and dysdifferentiation mesenchymal precursors. (weekly oral gavage with 0.125 mg (5000 IU)/100g body weight) omental tissue were histological examinated. At end experiment (9 monhs), adaptive changes to...
The evolution of reconstructive methods for defects the human body cannot yet replace use flap surgery. Research is still preoccupied with ideal techniques offering best chances survival flaps. In our study, we investigated effects cold atmospheric plasma (CAP), N-nitro-L-arginine methyl ester (L-NAME), and platelet-rich (PRP) injectable solutions on using an in vivo model. Twenty-four Wistar rats (four groups) had McFarlane raised CAP, L-NAME, PRP substances tested through a single dose...
Machine learning is a branch of artificial intelligence that allows computer systems to learn directly from examples, data, and experience. Statistical modeling more about finding connections between variables consequently the impact these relationships, while also catering for prediction. It should be clear two methodologies are different in terms their purpose, despite fact they use similar means get there. The evaluation machine algorithm uses set tests validate its accuracy. Although,...
Canine morbillivirus, also known as canine distemper virus (CDV), is the causative agent of (CD), which a serious contagious disease canines, large felids, and, occasionally, raccoons. This study included seven raccoons from Timisoara Zoological Garden, Romania. CDV was detected using RT-qPCR on blood samples, but several other exams were performed—clinical, bacteriological, immunohistochemistry (IHC) and histopathology, toxicological screening, necropsy—which confirmed infection. Severe...
(1) Osteoarthritis (OA) is a progressive joint degenerative disease that currently has no cure. Limitations in the development of innovative modifying therapies are related to complexity underlying pathogenic mechanisms. In addition, there unmet need for efficient drug delivery methods. Magnetic nanoparticles (MNPs) have been proposed as an modality bioactive molecules within OA joints, limiting side effects associated with systemic delivery. We previously demonstrated MNP's role increasing...
Biodegradable alloys in Mg have the advantages of traditional metallic materials and those biodegradable polymers with superior strength, lower density ideal rigidity for fixing bone fractures. The biocompatibility biodegradability five concentrations Mg-0.5Ca-xZr used were assessed using clinical laboratory examinations that followed over time: tissue reaction, histological imaging (RX, CT SEM) evolution at 1, 2, 4 8 weeks after implant. main purpose this study was to investigate vivo...