- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Liver Disease Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neuroendocrine Tumor Research Advances
- Liver Disease and Transplantation
- Gallbladder and Bile Duct Disorders
- Esophageal and GI Pathology
- Hepatitis C virus research
- Appendicitis Diagnosis and Management
- Organ Transplantation Techniques and Outcomes
- Hematological disorders and diagnostics
- Hepatocellular Carcinoma Treatment and Prognosis
- Infectious Diseases and Tuberculosis
- Intraperitoneal and Appendiceal Malignancies
- Cerebrospinal fluid and hydrocephalus
- Orthopedic Infections and Treatments
- Adrenal and Paraganglionic Tumors
- Amoebic Infections and Treatments
- Hormonal Regulation and Hypertension
- Sinusitis and nasal conditions
- Cancer, Lipids, and Metabolism
- Renal cell carcinoma treatment
- Nanoplatforms for cancer theranostics
- Spinal Dysraphism and Malformations
Grigore T. Popa University of Medicine and Pharmacy
2014-2025
Spitalul Clinic Judeţean de Urgenţe "Sf. Spiridon" Iaşi
2017-2024
Spitalul Clinic C.F. Iasi
2019
National Confidential Enquiry into Patient Outcome and Death
2017
Background: Neuroendocrine tumors are that can develop in any organ but show a predilection for the pancreas. These be secreting or non-secreting tumors, they well differentiated poorly differentiated, neuroendocrine carcinomas. Surgical treatment is only with curative intent, postoperatively, it shows an increased incidence of postoperative pancreatic fistulas. Methods: We carried out retrospective study which included 26 patients and carcinomas, whom we performed cephalic...
Abdominopelvic actinomycosis is a rare chronic or subacute bacterial infection caused by Actinomyces israelii, Gram-positive anaerobic bacterium that normally colonizes the digestive and genital tracts, clinically presented as an inflammatory mass abscess formation.We reviewed medical records of patients from our clinic with abdominopelvic who underwent surgery between 2002 2022. In this period, 28 cases (9 men 19 women) were treated. The mean age was 43.36 years they hospitalized for tumors...
Pancreaticoduodenectomy is the best treatment for patients with malignant tumors of pancreatic head. However, procedure also recommended in some benign tumors. The posterior approach allows early dissection superior mesenteric artery, portal vein and retroportal lamina, before any or digestive transection. We present a 42 year old woman diagnosed tumor. clinical biological data suggested diagnosis insulinoma. computed tomography showed nodule located head typical vascular pattern endocrine...
This case report underscores the importance of utilizing E-VAC (endoscopic vacuum-assisted closure) in treatment a perforated duodenal ulcer complicated by formation subphrenic abscess and septic shock. It showcases how can effectively mitigate risk further complications, such as leakage, bleeding, or rupture, which are more commonly associated with traditional methods like stents, clips, sutures. As result, there is significant reduction mortality rates. A accompanied represents critical...
Background and Objectives: A positive pathological circumferential resection margin is a key prognostic factor in rectal cancer surgery. The point of this prospective study was to see how well different MRI parameters could predict (pCRM) people who had been diagnosed with adenocarcinoma, either on their own or when used together. Materials Methods: Between November 2019 February 2023, total 112 patients were enrolled followed up for 36-month period. predictors such as (mCRM), presence...
A unitary model of drug release dynamics is proposed, assuming that the polymer–drug system can be assimilated into a multifractal mathematical object. Then, we made description implies, via Scale Relativity Theory, functionality continuous and undifferentiable curves (fractal or curves), possibly leading to holographic-like behaviors. At such conjuncture, Schrödinger Madelung scenarios become compatible: in scenario, various modes “mimicked” (via period doubling, damped oscillations,...
Introduction . During the past decades, safety of pancreatoduodenectomy has improved, with low mortality and reduced morbidity, particularly in centers extensive experience. Emergency is an uncommon event, for treatment pancreaticoduodenal trauma, bleeding, or perforation. We herein present a single center experience concerning nontrauma emergency bleeding. Methods From January 2007 to December 2015, from population 134 PD (70 males 64 females, mean age 62.2, range 34–82), 5 patients (3.7%;...
Background . Pancreaticoduodenectomy is the potentially curative treatment for malignant and several benign conditions of pancreatic head periampullary region. While performing pancreaticoduodenectomy, early neck division may be impossible or inadequate in case hepatic artery anatomic variants, suspected involvement superior mesenteric vessels, intraductal papillary mucinous neoplasm, bleeding pseudoaneurysm. Our work aims to highlight a particular hind right approach pancreaticoduodenectomy...
Background and Objectives: Postoperative pancreatic fistula after cephalic pancreatoduodenectomy (CPD) is still the leading cause of postoperative morbidity, entailing long hospital stay costs or even death. The aim this study was to propose use morphologic parameters based on a preoperative multisequence computer tomography (CT) scan in predicting clinically relevant (CRPF) risk score multiple regression analysis. Materials Methods: For 78 consecutive patients with CPD, we measured...
Non-alcoholic fatty liver disease (NAFLD) has gained attention in the last few years due to its increasing prevalence worldwide becoming a global epidemic. This review aims discuss latest recommendations regarding diagnosis and treatment of NAFLD-associated HCC remaining challenges. Thus, there is high amount data derived from basic clinical studies that revealed molecular pathways which drive hepatocellular carcinoma (HCC). Based on these findings, new prevention, surveillance strategies...
Osteoarticular tuberculosis (OATB) Aim: The authors made a clinical morphological assessment of tissue samples from patients admitted in Surgical Departments the Emergency County Hospital Craiova, Romania, between 1990 and 2015, proved as presenting tuberculous lesions spine Department Pathology same Hospital.The studied material consisted bone, joint sometimes muscle fragments resulted biopsies or surgical excisions 7 cases coming out 54 investigated above-mentioned period time, where...
In the frame of Higuchi's type functionality, this paper presents anisotropy influences on drug delivery mechanisms through joint invariant functions to simultaneous actions two SL(2R) isomorphic groups. Then, a new equation for mechanism, independent polymer matrix and/or drug, is proposed.
Machine learning is a branch of artificial intelligence that allows computer systems to learn directly from examples, data, and experience. Statistical modeling more about finding connections between variables consequently the impact these relationships, while also catering for prediction. It should be clear two methodologies are different in terms their purpose, despite fact they use similar means get there. The evaluation machine algorithm uses set tests validate its accuracy. Although,...