A5091029850- Nanoparticle-Based Drug Delivery
- Bone Tissue Engineering Materials
- Polymer Surface Interaction Studies
- biodegradable polymer synthesis and properties
- Nanocomposite Films for Food Packaging
- Electrospun Nanofibers in Biomedical Applications
- Hydrogels: synthesis, properties, applications
- Characterization and Applications of Magnetic Nanoparticles
- Bone and Dental Protein Studies
- Advanced Drug Delivery Systems
- Calcium Carbonate Crystallization and Inhibition
- Dendrimers and Hyperbranched Polymers
- Biotin and Related Studies
- Advanced Polymer Synthesis and Characterization
- Periodontal Regeneration and Treatments
- 3D Printing in Biomedical Research
- Orthopaedic implants and arthroplasty
- Graphene and Nanomaterials Applications
- nanoparticles nucleation surface interactions
- Silk-based biomaterials and applications
- Advanced Sensor and Energy Harvesting Materials
- Lanthanide and Transition Metal Complexes
- Ion-surface interactions and analysis
- Nanoplatforms for cancer theranostics
- Wound Healing and Treatments
Université Grenoble Alpes
2025
CEA LETI
2025
CEA Grenoble
2025
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2025
Grigore T. Popa University of Medicine and Pharmacy
2015-2024
Institutul de Chimie Macromoleculară Petru Poni
2013-2015
Gheorghe Asachi Technical University of Iași
2011-2012
A method for the preparation of magnetite/chitosan composite nanoparticles was developed. Colloidal magnetite particles (Fe_3O_4 produced by co-precipitation and stabilized in suspension adding a non-ionic surfactant (Pluronic F127) were subsequently covered with layer chitosan (CS) prepared ionotropic gelation using sodium tripolyphosphate (STPP) as crosslinking agent. The products characterized terms following parameters: size distribution \zeta-potential (by laser diffraction analysis),...
Considering the future trends of biomaterials, current studies are focused on corrosion resistance and mechanical properties new materials that need to be considered in process strengthening alloys with additive non-toxic elements. Many kinds titanium different biocompatible elements (Mo, Si, Zr, etc.,) have been recently developed for their similar human bone. Four were obtained investigated regarding microstructure, mechanical, chemical, biological behavior (in vitro vivo evaluation), as...
The objective of this work was to analyze the in vitro and vivo tests a novel Mg-based biodegradable alloy—Mg-0.5%Ca—with various amounts Zn (0.5, 1, 1.5, 2.0, 3.0 wt.%). In terms biocompatibility, MTT Calcein-AM cell viability assays, performed on MG-63 line through extract method, revealed that all five alloy extracts are non-cytotoxic at an extraction ratio 0.025 g per mL culture medium. histological analysis, Mg-0.5Ca-1.5Zn demonstrated exceptional potential for stimulating bone...
Background and objectives: Cancer is the second leading cause of death globally, an alarming but expected increase. In comparison to other types cancer, malignant bone tumors are unusual their treatment a real challenge. This paper’s main purpose study potential application composite scaffolds based on biopolymers calcium phosphates with inclusion magnetic nanoparticles in combination therapy for tumors. Materials Methods: The first step was investigate if X-rays could modify scaffolds’...
A considerable interest in cancer research is represented by the development of magnetic nanoparticles based on biofunctionalized polymers for controlled-release systems hydrophobic chemotherapeutic drugs targeted only to tumor sites, without affecting normal cells. The objective paper present synthesis and vitro evaluation nanocomposites that include a core able direct target, polymeric surface shell provides stabilization multi-functionality, agent, Paclitaxel (PTX), biotin recognition...
In light of the increasing resistance pathogenic microorganisms to action antibiotics, essential oils extracted from plants with therapeutic activity provide a significant alternative obtaining dressings for treatment skin wounds. The encapsulation in an amphiphilic gel network allows better dispersion and preservation hydrophobic bioactive substances while promoting their prolonged release. this study, we focused on development poly (vinyl alcohol) (PVA)/poly (ethylene brassylate-co-squaric...
Squaric acid (SA) is a compound with potential to crosslink biomacromolecules. Although SA has become over the last years well-known crosslinking agent as result of its good biocompatibility, glutaraldehyde (GA), proven cytotoxicity still one most used crosslinkers develop nanomaterials. In this regard, novelty present study consists in determining whether it may be possible substitute GA new bifunctional and biocompatible compound, such SA, process enzyme immobilization on surface magnetic...
The tendency of population aging is continuously increasing, which directly correlated with a significative number associated pathologies. Several metabolic bone diseases such as osteoporosis or chronic kidney disease–mineral and disorders involve high risk fractures. Due to the specific fragility, bones will not self-heal supportive treatments are necessary. Implantable substitutes, component tissue engineering (BTE) strategy, proved be an efficient solution for this issue. aim study was...