- Geology and Paleoclimatology Research
- Paleontology and Stratigraphy of Fossils
- Geological and Geophysical Studies
- Hydrocarbon exploration and reservoir analysis
- Geological formations and processes
- Extraction and Separation Processes
- Climate change and permafrost
- Radioactive element chemistry and processing
- Groundwater and Isotope Geochemistry
- Geochemistry and Geochronology of Asian Mineral Deposits
- Evolution and Paleontology Studies
- Plant Water Relations and Carbon Dynamics
- Chemical Synthesis and Characterization
- Geological and Geochemical Analysis
- Geomagnetism and Paleomagnetism Studies
- Enzyme Structure and Function
- Geochemistry and Elemental Analysis
- RNA modifications and cancer
- 14-3-3 protein interactions
- Microbial Natural Products and Biosynthesis
- Supramolecular Chemistry and Complexes
- RNA regulation and disease
- Cryospheric studies and observations
- Soil Carbon and Nitrogen Dynamics
- Structural Integrity and Reliability Analysis
Chinese Academy of Sciences
2013-2024
Institute of Tibetan Plateau Research
2012-2024
Guangdong Pharmaceutical University
2022
Xian Central Hospital
2021
Center for Excellence in Tibetan Plateau Earth Sciences
2011-2020
Changchun Institute of Applied Chemistry
2004-2020
University of Chinese Academy of Sciences
2020
Icahn School of Medicine at Mount Sinai
2019
Sema4 (United States)
2019
Emory University
2012-2015
The 14-3-3 family of phosphoserine/threonine-recognition proteins engage multiple nodes in signaling networks that control diverse physiological and pathophysiological functions have emerged as promising therapeutic targets for such diseases cancer neurodegenerative disorders. Thus, small molecule modulators are much needed agents chemical biology investigations development. To analyze function modulate its activity, we conducted a screen identified...
Key Points The uplift event (~10.5–8 Ma) revealed by glycerol dialkyl tetraethers temperature records from the Xining Basin is synchronous with regional drying cooling amplitude over land less than that ocean during CO 2 ‐dominated Late Miocene (~7–5.4 Tectonic forcing, rather p , dominated continental climate patterns and ecosystem transitions
Abstract BACKGROUND Spodoptera frugiperda (Lepidoptera: Noctuidae) is one of the world's major agriculture pests, causing significant crop damage and serious economic losses. As S. has developed widespread resistance, environmentally friendly insecticides are urgently needed. Therefore, searching for natural antifeedant or insecticidal lead compounds become imperative. RESULTS Three new indole diterpenoids, paspamine A (1), B (2), paspalitrem D (3), along with nine known ones (compounds...
Abstract Background Thorium is a natural radioactive element which often associated in different minerals with rare earth elements ( REs ). In order to satisfy application for nuclear fuel, thorium should be separated from and other elements. Calixarene derivatives have been proved excellent extractants towards . this study, p ‐phosphorylated calixarene derivative was applied extraction separation of Results calix[4]arene, 5,11,17,23‐tetra(diethoxyphosphoryl)‐...
Abstract Paleoaltimetric reconstructions of the southern Tibetan Plateau (TP) are crucial to understand processes and mechanisms concomitant with tectonic collision Indian Eurasian continental plates. We measured branched glycerol dialkyl tetraether (brGDGT) indices from 88 surface soils TP found that alkaline exhibited lower MBT′ MBT′/CBT‐derived MAT (mean annual temperature), while a strong correlation altitude ( R 2 = 0.84; n 63) for all localities neutral acidic soils. Differently, we...
Between 2010 and 2011, this project collected analyzed forty‐nine superficial soil samples, for wax‐derived n ‐alkane δ D values ( wax ), along a south to north transect of the Tibetan Plateau, from southern Plateau Nepalese Himalayas, passing through Nam Co basin, Qilian Mountains. Twenty‐two paired river water samples were also northeastern Tibet during period RW ). The become progressively more negative northward ∼27.5°N, reach minimum at ∼30.6°N (Nam basin). North 35°N, isotope increase,...
The wastewater discharged from the rare earth (RE) industry generally contains a high level of calcium and magnesium sulfates, which confers permanent hardness causes difficulties in recycling this wastewater.
Abstract The extraction of trivalent rare earths (RE) from nitrate solutions with di‐(2‐ethylhexyl) 2‐ethylhexyl phosphonate (DEHEHP, B) and synergistic combined 1‐phenyl‐3‐methyl‐4‐benzoyl ‐pyrazolone‐5 (HPMBP, HA) were investigated. distribution ratios demonstrate a distinct "tetra effect," Y lies between Tb Dy when DEHEHP is used as single extractant for RE. According to the corresponding separation factors (SF12) adjacent pairs earths, it could be concluded that employed La other light...