Kimberly N. Bekas

ORCID: 0000-0002-2970-3549
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About
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Research Areas
  • Genetics, Aging, and Longevity in Model Organisms
  • CRISPR and Genetic Engineering
  • RNA Interference and Gene Delivery
  • RNA regulation and disease
  • Circadian rhythm and melatonin
  • Reproductive Biology and Fertility

University of Iowa
2020-2022

Abstract Asymmetric cell division (ACD) is a fundamental mechanism of fate specification and adult tissue homeostasis. In C. elegans , the Wnt/β-catenin asymmetry (WβA) pathway regulates ACDs throughout embryonic larval development. Under control Wnt ligand-induced polarity, transcription factor POP-1/TCF functions with coactivator SYS-1/β-catenin to activate gene expression in signaled or, absence coactivator, repress target genes unsignaled daughter cell. To date, investigation Groucho...

10.1101/2022.01.10.475695 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2022-01-11
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