- HIV, Drug Use, Sexual Risk
- Opioid Use Disorder Treatment
- Substance Abuse Treatment and Outcomes
- Syphilis Diagnosis and Treatment
- Reproductive tract infections research
- Pregnancy and preeclampsia studies
- HIV, TB, and STIs Epidemiology
- HIV/AIDS Research and Interventions
- Nutritional Studies and Diet
- LGBTQ Health, Identity, and Policy
- Socioeconomic Development in Asia
- Maternal and fetal healthcare
- Preterm Birth and Chorioamnionitis
- Reproductive Health and Contraception
- Healthcare Decision-Making and Restraints
- Birth, Development, and Health
- Obesity, Physical Activity, Diet
- Sleep and related disorders
- Hepatitis C virus research
- Global Maternal and Child Health
- Statistical Methods in Clinical Trials
- Gestational Diabetes Research and Management
- Family Dynamics and Relationships
- Sex work and related issues
- Adolescent Sexual and Reproductive Health
Sun Yat-sen University
2022-2025
Is paternal age associated with neonatal outcomes? Paternal is independently preterm birth (PTB) and caesarean section. Advanced maternal has long been recognized as a major risk factor for adverse outcomes. However, the association between outcomes are not well established, yet it biologically plausible that an increasing number of genetic epigenetic sperm abnormalities in older males may contribute to This population-based cohort study was based on National Free Preconception Checkups...
Adverse pregnancy outcomes (APOs) share clinical features and risk factors with cardiovascular disease there is an increasing prevalence of hypertension among reproductive women. However, the associations between maternal preconception blood pressure (BP) APOs remain controversial inconclusive.
BACKGROUND: The association of hypertension and blood pressure control with fecundability among women is not yet elucidated. purpose this study was to evaluate the hypothesis that maternal preconception would be associated reduced could reduce excess risk. METHODS: Using National Free Preconception Checkup Projects in Guangdong Province, China, 1422 couples whose female partners had been diagnosed 997 703 reference were without included prospective cohort study. Fecundability measured by...
To evaluate the effectiveness of preventive and control measures for congenital syphilis (CS) implemented since 2012 in Guangdong Province, China, assess epidemic trend near future.The interrupted time series analysis was conducted to compare changes slope level CS notification rate from 2005 2020 Province its three regions with different economic developmental levels. The ARIMA model established predict new case number 2021.A total 12,687 cases were reported 2020. province had been...
Background Relapse is a great barrier to improving the effectiveness of methadone maintenance treatment (MMT). Participants with different durations could vary in their compliance MMT, which may lead levels relapse risk. This study aims identify risk factors for and assess MMT participants durations. Method retrospective used data collected from seven clinics Guangdong Province, China, January 2010 April 2017. Newly enrolled who received 6 ( n = 903) 12 710) months consecutive complete were...
Evidence on the association between dietary patterns and sleep disorders is limited controversial. In addition, studies evaluating effect of have seldom considered critical role obesity. We aimed to explore obesity-related evaluate their impact using data from National Health Nutrition Examination Survey 2005-2014. total, 19,892 participants aged over 20 years with two-day recalls were enrolled. Obesity-related explaining most variance in waist circumference BMI simultaneously extracted...
Background Duration of marriage (DoM) and age are important characteristics married individuals, who the critical population for eliminating mother-to-child transmission (MTCT) syphilis. A deep understanding preconception syphilis seroprevalence (PSS) its distribution among this may be able to help eliminate MTCT. However, few population-based epidemiological studies have been focused on group, association DoM with PSS remains unclear. Methodology/Principal findings This study used data from...
Many methadone maintenance treatment (MMT) participants experienced a tapering phase. The benefit of is based on balance between meeting the desire to reduce dose and reduction in relapse. We aimed develop validate nomogram assess relapse risk after tapering. developed internally validated for assessment before 432 with non-Guangzhou region Guangdong, China, externally it 117 Guangzhou. Cox regression analysis showed that taper start week (
Abstract Background Methadone maintenance treatment (MMT) has been implemented in China for nearly two decades, with a significant decrease the number of participants recent years. However, there is lack comprehensive research focusing on long-term effectiveness context this decline, especially from perspectives MMT themselves. This study aims to address gap by examining benefits and challenges experienced China, uncover potential causes participant numbers improve program. Methods We...
Although previous studies have reported the variables that influence opioid use or dropout among participants receiving methadone treatment, limited attention has been given to related transitions no use, and dropout.
Background Syphilis remains a major public health problem worldwide, and its prevention requires knowledge of factors that go beyond the individual-level. However, most syphilis-related studies have focused on individual-level regional-level factors, neglecting couple-level factors. Thus, this study aimed to explore determinants syphilis infection among heterosexual married couples. Methods This population-based cross-sectional used data from couples who participated in National Free...
Background Recurrent dropout often occurs among participants receiving methadone maintenance treatment (MMT), which negatively affects effectiveness. However, few researchers focused on this phenomenon including those in China. This study examined systematically factors associated with based recurrent events analysis Chinese MMT participants.Methods retrospective involved who firstly enrolled program between 2006 and 2017 of nine clinics the Guangdong Province. The influencing were...
Abstract Relapse is a great barrier to improving the effectiveness of methadone maintenance treatment (MMT). Participants with different durations could vary in compliance MMT, which may lead levels relapse risk. This study aims identify risk factors for and assess MMT participants durations. retrospective used data collected from 9 clinics Guangdong Province, China January 2010 April 2017. Newly enrolled who received 6 (n = 903) 12 710) months consecutive complete were include. We selected...
Abstract Background: The re-emergence of congenital syphilis (CS) was witnessed since the 1990s over globe, including China. country, therefore, carried out prevention and control measures in an all-around way 2010, large-scale screening for pregnant women, providing standard treatment follow-up management both infected mothers their infants, as well supportive strategies from government response. However, there is a lack published evaluation these when deadline final goal (CS notification...