- Palliative Care and End-of-Life Issues
- Cancer survivorship and care
- Childhood Cancer Survivors' Quality of Life
- Neuroendocrine Tumor Research Advances
- Pancreatic and Hepatic Oncology Research
- Cancer-related cognitive impairment studies
- Lung Cancer Research Studies
- Neuroblastoma Research and Treatments
- Economic and Financial Impacts of Cancer
- COVID-19 and healthcare impacts
- Pancreatitis Pathology and Treatment
- Complementary and Alternative Medicine Studies
- Healthcare cost, quality, practices
- Intestinal and Peritoneal Adhesions
- BRCA gene mutations in cancer
- Abdominal Surgery and Complications
- Appendicitis Diagnosis and Management
- CRISPR and Genetic Engineering
- Frailty in Older Adults
- Hepatocellular Carcinoma Treatment and Prognosis
- Pain Management and Opioid Use
- Opioid Use Disorder Treatment
- Viral Infectious Diseases and Gene Expression in Insects
- Text Readability and Simplification
- Health Literacy and Information Accessibility
The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute
2007-2024
The Ohio State University
2003-2022
The Ohio State University Wexner Medical Center
2007-2020
Nationwide Children's Hospital
2003
ABSTRACT Recombinant adeno-associated virus (rAAV) vectors are promising human gene transfer vectors, because they mediate long-term expression in vivo. The vector DNA form responsible for sustained has not been clearly defined, but it presumed that the integrates to some degree and persists this manner. Using two independent methods, we were unable identify rAAV integrants mouse muscle. In first approach, recover host cell-vector junctions from a lambda phage library generated using...
The novel coronavirus, SARS-CoV-2, was first detected as a respiratory illness in December 2019 Wuhan City, China. Since then, coronavirus disease (COVID-19) has impacted every aspect of our lives worldwide. In time when terms such social distancing and flattening the curve have become part vernacular, it is essential that we understand what measures can be implemented to protect patients healthcare workers. Undoubtedly, providers had rapidly alter care delivery models while simultaneously...
Purpose Central line–associated bloodstream infection (CLABSI) rates have been consistently high at an academic comprehensive cancer hospital. CLABSI prevention bundles can mitigate central line infections, and many components focus on nursing practice. Identification of barriers to maintaining adherence these elements is not always assessed or addressed. The purpose this project was increase practices implement a sustainable program elevate nurses’ skills documentation bundle components....
Palliative care (PC) serves a valuable role throughout the disease trajectory for adolescents and young adults (AYAs) living with cancer. A 3-year retrospective chart review was performed to characterize AYA PC referral patterns in patients aged 18-39 years identify strategies improving access. Despite known benefits, referrals during oncologic treatment occurred only small percentage of eligible (8.4%), largely inpatient setting (73%), were more likely specific cancer types high symptom...
Treatment Summaries and Survivorship Care Plans (TS/SCPs) may be difficult for patients to comprehend because of readability, magnitude information, complex medical verbiage.Readability scores were calculated TS/SCP templates including ASCO, Oncolink, Journey Forward, the authors' institution. The Simple Measure Gobbledygook (SMOG) index, Flesch-Kincaid reading grade level, Coleman-Liau Index, Gunning Fog index used assess readability.The ease blank ASCO ranged from 47.4 53.3, requiring a...
It is estimated that there are >18 million cancer survivors in the United States, and a growing number of survivorship programs across country to care for these individuals. There clear need care; however, evidence still emerging on how best operationalize guidance from nationally recognized organizations clinical practice guidelines.
A comprehensive cancer center in the midwestern United States implemented a stakeholder-engaged quality improvement process to extend its existing one-year advanced practice provider (APP) fellowship program consisting of general oncology education and clinical experience include an additional survivorship rotation. APP alumni stakeholders reported noticeable benefits greater importance attributed participation, validating inclusion clinic rotation as part program.
Margin status is a predictor of outcome for patients with liver malignancies, although what constitutes negative margin controversial. Traditionally, the completeness resection estimated by surgical histopathology resected specimen margin, despite in situ being potentially more important. The true often altered parenchymal transection techniques. authors propose that cytologic assessment specific determining margin.A total 84 primary or metastatic tumors who were undergoing enrolled this...
Mounting evidence suggests patients diagnosed with cancer may be at increased risk for opioid misuse and diversion. Substance use disorders (SUDs), involving prescription medications and/or illegal substances, significantly compromise the ability of healthcare professionals to deliver high-quality care. A substance screening pilot was conducted in ambulatory oncology clinics a large hospital midwestern United States. In this article, authors present results from quality improvement project....
14 Background: Holistic oncology care combines cancer treatment with supportive to meet the physical and psychosocial needs of survivor. Advanced Practice Providers (APPs) are prepared deliver high-quality, comprehensive vital survivorship as number survivors continues rise. At a Midwest Comprehensive Cancer Center (CCC), an APP oncology-specific fellowship is innovative year-long postgraduate clinical training program. For first time, 2 week rotation through this CCC’s department will be...
58 Background: The Commission on Cancer (CoC) enacted a new accreditation standard (3.3) in 2012 to ensure cancer survivors treated with curative intent receive Treatment Summary and Survivorship Care Plan (SCP) upon treatment completion. Accredited institutions reported challenges meeting the such as lengthy completion time, lack of reimbursement, limited personnel. In 2014, CoC clarified 3.3 allow 5 year phased launch for be compliant by 2019. Yet, academic centers continued report...