A5072362670- Electric Power System Optimization
- Monoclonal and Polyclonal Antibodies Research
- Optimal Power Flow Distribution
- Power System Reliability and Maintenance
- Chemical Synthesis and Analysis
- Supply Chain and Inventory Management
- Big Data and Business Intelligence
- Protein purification and stability
- Glycosylation and Glycoproteins Research
- Vehicle Routing Optimization Methods
- Biochemical and Structural Characterization
- Risk and Portfolio Optimization
- Bacteriophages and microbial interactions
- Reliability and Maintenance Optimization
- Smart Grid Energy Management
- Viral Infectious Diseases and Gene Expression in Insects
- Energy, Environment, and Transportation Policies
- Consumer Market Behavior and Pricing
General Motors (United States)
2016-2023
Center for Cancer Research
2005-2007
Target (United States)
2005-2007
National Cancer Institute
2005-2006
Frederick National Laboratory for Cancer Research
2006
We investigated whether the T7 system of phage display could produce peptide libraries greater diversity than M13 due to differing processes lytic and filamentous morphogenesis. Using a bioinformatics-assisted computational approach, collections random sequences obtained from 12-mer library (X(12)) 7-mer disulfide-constrained (CX(7)C) were analyzed compared with populations New England BioLabs' Ph.D.-12 Ph.D.-C7C libraries. Based on this analysis, constructed have fewer amino acid biases,...
Abstract Background Amino acid sequence diversity is introduced into a phage-displayed peptide library by randomizing oligonucleotide DNA. We recently evaluated the of libraries displayed on T7 lytic phage and M13 filamentous showed that can display more diverse amino repertoire due to differing processes viral morphogenesis. Methods In this study, we compared 12-mer randomized using codon-corrected trinucleotide cassettes with an constructed degenerate codon randomization method. Results...
Most power grid systems are operated to be N-1 secure, meaning that the system can withstand failure of any one component. There is increasing interest in more stringent security standards, where must able survive (nearly) simultaneous k components (i.e., N-k). However, this improved reliability criterion significantly increases number contingency scenarios considered when solving unit commitment problem. Additional computational complexity introduced taking into account transmission...
General Motors (GM) vehicles have more than 100 customer-facing features, known as vehicle content. Decisions about how to package and price these features a significant impact on our customers’ experiences GM’s business results. Vehicle are assigned standard, optional, or unavailable different trim levels, resulting in an enormous combinatorial solution space. content optimization (VCO) combines customer market research, discrete choice models, custom multiobjective nonlinear algorithms...
Abstract We consider the problem of determining capacity to assign each arc in a given network, subject uncertainty supply and/or demand node. This design underlies many real‐world applications, such as power transmission and telecommunications networks. first case where set supply/demand scenarios are provided, we must determine minimum‐cost capacities that feasible flow exists for scenario. briefly review existing theoretical approaches solving this explore implementation strategies reduce...