A5019064886- 2D Materials and Applications
- Topological Materials and Phenomena
- Advanced Thermoelectric Materials and Devices
- Osteoarthritis Treatment and Mechanisms
- Protease and Inhibitor Mechanisms
- Inflammatory mediators and NSAID effects
- Graphene research and applications
Sun Yat-sen University
2024
Fifth Affiliated Hospital of Sun Yat-sen University
2024
The University of Western Australia
2019
Osteoarthritis (OA) is a highly incident total joint degenerative disease with cartilage degeneration as the primary pathogenesis. The matrix mainly composed of collagen, protein hallmark triple-helix structure, which unfolds collagen degradation on surface. A hybridizing peptide (CHP) synthetic that binds denatured triple helix, conferring potential disease-targeting possibility for early-stage OA. Here, we constructed an albumin nanoparticle (An) conjugated CHP, loaded...