- Advanced Proteomics Techniques and Applications
- Viral Infectious Diseases and Gene Expression in Insects
- Thermal Radiation and Cooling Technologies
- Strong Light-Matter Interactions
- Gene Regulatory Network Analysis
- Ion channel regulation and function
- Plant Disease Resistance and Genetics
- Microbial Metabolic Engineering and Bioproduction
- Quantum optics and atomic interactions
University of Freiburg
2022-2024
Czech Academy of Sciences, Institute of Physics
2024
Biological systems are frequently analyzed by means of mechanistic mathematical models. In order to infer model parameters and provide a useful that can be employed for understanding hypothesis testing, the is often calibrated on quantitative, time-resolved data. To do so, it typically important compare experimental measurements over broad time ranges various conditions, e.g. perturbations biological system. However, most established techniques such as Western blot, or quantitative real-time...
Abstract Calcium is a ubiquitous secondary messenger which regulates many cellular processes. Recently, we have shown that subpopulation of glioblastoma cells can intrinsically generate calcium oscillations drive proliferative signalling. Here, set out to investigate whether such cancer cell autonomous are also present in brain tumours. Employing longitudinal intravital two-photon microscopy awake mice, demonstrate metastases melanoma and lung exhibit spontaneous vivo along the metastatic...
Abstract Biological systems are frequently analyzed by means of mechanistic mathematical models. In order to infer model parameters and provide a useful that can be employed for understanding hypothesis testing, the is often calibrated on quantitative, time-resolved data. To do so, it typically important compare experimental measurements over broad time ranges various conditions, e.g. perturbations biological system. However, most established techniques such as Western blot, or quantitative...
Closely-spaced quantum emitters coherently sharing excitation can release their energy faster than suggested by a simple sum over individual emission rates - phenomenon known as superradiance. Here, we show that the assumption of closely-spaced be relaxed in context resonant transfer, instead finding certain symmetrical arrangements donors are just effective. We derive exact expressions for superradiant fidelity such situations, some surprising results complete suppression rate single...