A5103075930- Drug Transport and Resistance Mechanisms
- Advanced Drug Delivery Systems
- Paranormal Experiences and Beliefs
- Amino Acid Enzymes and Metabolism
- Pharmacological Effects and Toxicity Studies
- Biofield Effects and Biophysics
- HIV/AIDS drug development and treatment
- Nanoparticle-Based Drug Delivery
- Retinal Diseases and Treatments
- Ocular Surface and Contact Lens
- RNA Interference and Gene Delivery
- Quantum Mechanics and Applications
- Neonatal Health and Biochemistry
- Pharmacogenetics and Drug Metabolism
- EEG and Brain-Computer Interfaces
- Cytomegalovirus and herpesvirus research
- Biotin and Related Studies
- Metabolism and Genetic Disorders
- Crystallization and Solubility Studies
- Systemic Lupus Erythematosus Research
- Folate and B Vitamins Research
- X-ray Diffraction in Crystallography
- Herpesvirus Infections and Treatments
- Advancements in Transdermal Drug Delivery
- Vitamin C and Antioxidants Research
West Bengal University of Animal and Fishery Sciences
2023
University of Missouri–Kansas City
2012-2021
Maulana Abul Kalam Azad University of Technology, West Bengal
2007-2015
Indian Institute of Engineering Science and Technology, Shibpur
2013-2014
University of Kentucky
2011
University of Kansas
1997-2005
Augusta University
2004
Kansas City University
2003
The University of Texas Medical Branch at Galveston
1992
University of Calcutta
1986-1990
The purpose of this study was to evaluate in vitro interactions commercially obtained pure herbal constituents with p-glycoprotein P-gp and cytochrome P-450 3A4 (CYP3A4) activities, which can further modulate the transcellular transport metabolism kinetics orally administered drugs. Caco-2 cells grown presence 0.25 μmol/L 1α,25-dihydroxy vitamin D3 multidrug-resistant 1 (MDR1) transfected MDCK were used as models effect purified (quercetin, hypericin, hyperforin from St. John's wort,...
Efflux pumps such as P-glycoprotein (P-gp; MDR1) are believed to be a major barrier drug delivery. The purpose of this work was determine whether cornea and corneal epithelial cells expresses the functionally active P-gp efflux pump.Cultured rabbit primary (rPCECs) cell line (Statens Seruminstitut [SIRC] cells) were selected model. Rhodamine-123 (Rho-123), substrate, used probe. To confirm gene expression, RT-PCR performed with appropriate pairs primers for human MDR1. Subcloning,...
Topical drug administration for back of the eye delivery is extremely challenging due to presence protection mechanisms and physiological barriers. Self-assembled polymeric nanomicelles have emerged as promising vehicles delivery. Apart from serving an inert nanocarrier therapeutic agents, are known bypass mononuclear phagocytic system (MPS) efflux transporters thereby improving bioavailability. In this investigation, a highly efficacious biotinylated lipid prodrug cyclic cidofovir...