- Neonatal Respiratory Health Research
- Neonatal and fetal brain pathology
- Neonatal and Maternal Infections
- Cardiovascular Conditions and Treatments
- Congenital Heart Disease Studies
- Cardiac Arrest and Resuscitation
- Neonatal Health and Biochemistry
- Blood Coagulation and Thrombosis Mechanisms
- Parvovirus B19 Infection Studies
- Antibiotics Pharmacokinetics and Efficacy
- Central Venous Catheters and Hemodialysis
- Sepsis Diagnosis and Treatment
- Cytomegalovirus and herpesvirus research
- Congenital Diaphragmatic Hernia Studies
- Neuroscience of respiration and sleep
- Antifungal resistance and susceptibility
- Metabolism and Genetic Disorders
- Infant Nutrition and Health
- Cystic Fibrosis Research Advances
- Cardiac Arrhythmias and Treatments
- Transplantation: Methods and Outcomes
- Preterm Birth and Chorioamnionitis
- COVID-19 Impact on Reproduction
- Ultrasound in Clinical Applications
- Cerebral Venous Sinus Thrombosis
Bambino Gesù Children's Hospital
2015-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2022-2023
Agostino Gemelli University Polyclinic
2008-2020
Università Cattolica del Sacro Cuore
2006-2016
Universitätsklinikum Würzburg
2012
University of Würzburg
2012
Uniwersytecki Szpital Dziecięcy
2012
Children's Clinical University Hospital
2012
Catholic University of America
2011
Fairfax Neonatal Associates
2010
Subcutaneous fat necrosis (SCFN) in newborns is an uncommon and self-limiting non-infectious panniculitis. It can occur the first weeks of life full-term with hypoxic-ischemic encephalopathy who underwent therapeutic hypothermia. Hypercalcemia may develop has been implicated as cause several complications nephrocalcinosis. previously reported to appear only after resolution skin lesions. Herein, we report how hypercalcemia be evident already at diagnosis subcutaneous hypothermia associated...
Abstract TBX4 gene, located on human chromosome 17q23.2, encodes for T-Box Transcription Factor 4, a transcription factor that belongs to the T-box gene family and it is involved in regulation of some embryonic developmental processes, with significant impact respiratory skeletal illnesses. Herein, we present case female neonate persistent pulmonary hypertension (PH) who underwent extracorporeal membrane oxygenation (ECMO) first day life then resulted have novel variant identified by...
Background: Neonatal acute liver failure (ALF) is a severe condition with mortality rate up to 70%. Human enterovirus (HEV) infections are associated serious diseases in newborns, including myocarditis, meningoencephalitis and, more rarely, ALF fulminant course.Methods: Cases of neonatal-onset were identified using the institutional clinical database. The history and data infants HEV infection collected by medical record revision. Viral testing nested real- time PCR (nRT-PCR) was performed...
(1) Background: Infections in pregnancy can lead to miscarriage, premature birth, infections newborns, and developmental disabilities babies. Infected infants, symptomatic at have long-term sequelae, asymptomatic babies are also increased risk of developing sensorineural outcomes. Targeted therapy the pregnant mother reduce fetal neonatal harm. (2) Aim study: To explore association between symptoms time onset sequelae infected children born from mothers who contracted an infection during...
A possible consequence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is the development an exacerbated thrombophilic status, and cerebral venous thrombosis (CVT) a rare but complication SARS-CoV-2 reported both in adults children. The present case report describes clinical course term neonate showing extended CVT unclear origin, whose mother had developed during third trimester pregnancy. We speculate that prothrombotic status induced by maternal may have played...
Administration of glucocorticoids and caffeine is a common therapeutic intervention in the neonatal period, but possible interactions between these substances are still unclear. The present study investigated effect different on expression surfactant protein (SP)-B, crucial for physiological function pulmonary surfactant. We measured levels SP-B, various SP-B transcription factors including erythroblastic leukemia viral oncogene homolog 4 (ErbB4) thyroid factor-1 (TTF-1), as well...
Objective: Echocardiographic flow patterns of patent ductus arteriosus (PDA) are useful to predict the development hemodynamically significant in premature infants. N-terminal pro-brain natriuretic peptide (NT-proBNP) concentrations seem be detect PDA. We investigated how NT-proBNP levels change on basis different during first day life, and whether might represent a reliable decision tool PDA management.Methods: Neonates with gestational age <32 weeks were assessed prospectively, using...
So-called lock therapy, consisting of high concentrations antimicrobials instilled into the lumen catheter, has been suggested avoid central venous catheter removal during fungal infection. We report a baby who developed catheter-related candidemia. Systemic antifungal treatment did not resolve Lock therapy with 0.3 mL ethanol 70% and micafungin sodium 5 mg/L was added to blood cultures became sterile.