A5025840245- Carcinogens and Genotoxicity Assessment
- Effects and risks of endocrine disrupting chemicals
- DNA Repair Mechanisms
- Additive Manufacturing Materials and Processes
- Additive Manufacturing and 3D Printing Technologies
- Traumatic Brain Injury and Neurovascular Disturbances
- Radiation Dose and Imaging
- Toxic Organic Pollutants Impact
- Traumatic Brain Injury Research
- Chemical Safety and Risk Management
- Musicology and Musical Analysis
- Prostate Cancer Treatment and Research
- Epigenetics and DNA Methylation
- Seedling growth and survival studies
- Molecular Biology Techniques and Applications
- Forest ecology and management
- Lignin and Wood Chemistry
- Music Technology and Sound Studies
- Air Quality and Health Impacts
- Radiology practices and education
- Cancer-related Molecular Pathways
- Advanced X-ray and CT Imaging
- Injection Molding Process and Properties
- Tree Root and Stability Studies
- Advanced Radiotherapy Techniques
University of Missouri
2024
KTH Royal Institute of Technology
2024
St George's, University of London
2015-2023
University of Missouri Hospital
2023
University of Alberta
2023
University of Wisconsin–Madison
2016-2022
Ames Research Center
2021
Victoria University of Wellington
2019
Queens College, CUNY
2019
Kingston University
2015-2016
The objective of this work is to compare the energy consumption associated with creation a small volume steel by wire-based additive-subtractive manufacturing and powder-based manufacturing. Additive growing area research, encompassing many different processes aimed at producing final products. However, additive lack ability achieve dimensional tolerance surface finish required for applications: i.e., post-processing could be required. Combining subtractive in one machine tool enables...
Epidemiologic data reveal that the incidence rate of prostate gland carcinoma among black population in United States (US) is several times higher than Nigerians. A collaborative study between two countries was undertaken, and blood hormone (testosterone [T], dihydrotestosterone [DHT], estrone [E1], estradiol [E2], prolactin [P1]), total acid phosphatase (TP), prostatic (PAP) profiles groups were compared. In US (patients controls) there significantly levels T (P < 0.01) E1 0.05) compared...
IntroductionOnline MRI guided adaptive radiotherapy (MRIgRT) is resource intensive. To maintain and increase uptake traditional roles responsibilities may need refining. This novel study aims to provide an in-depth understanding subsequent impact of the required deliver on-line MRIgRT by exploring current skills knowledge radiographers.MethodA purposive sampling approach was used invite radiographers, clinicians physicists from centres with experience participate. Focus Group Interviews were...
Mild traumatic brain injury (mTBI) induced by low-intensity blast (LIB) is a serious health problem affecting military service members and veterans. Our previous reports using single open-field LIB mouse model showed the absence of gross microscopic damage or necrosis in brain, while transmission electron microscopy (TEM) identified ultrastructural abnormalities myelin sheaths, mitochondria, synapses. The neurovascular unit (NVU), an anatomical functional system with multiple components,...
Sympatric species pairs of benthic and limnetic threespine stickleback ( Gasterosteus aculeatus L., 1758 complex) are an important example the role ecology in speciation nature. Four endemic known each appears to have diverged independently as a consequence adaptation alternative environments. Using specific ecological physical attributes hypothesized be their evolution, we focused search for further pairs. Now, two decades after last discovery, describe another benthic–limnetic pair from...
A graphic approach termed a Genetic Activity Profile (GAP) has been developed to display matrix of data on the genetic and related effects selected chemical agents. The profiles provide visual overview quantitative (doses) qualitative (test results) for each chemical. Either lowest effective dose (LED) or highest ineffective (HID) is recorded agent bioassay. Up 200 different test systems are represented across GAP. Bioassay organized according phylogeny organisms end points activity....
The Internet has become a common venue for meeting sex partners and planning participation in risky sexual behavior. In this article, we evaluate the first 18 months of Washington, DC, Department Health Internet-based Partner Notification (IPN) program early syphilis infections, using standard Centers Disease Control Prevention (CDC) Investigation Specialist (DIS) disposition codes, as well Health's IPN-specific outcomes pseudonymous partners.We analyzed DIS codes from all investigations...
Dose-related differences in the binding of DNA reactive intermediates for three environmentally important complex mixture particulate extracts and a well-studied carcinogen, benzo[a]pyrene (BaP), were examined female C-57 mice following multiple topical treatments ranging from 1 to 120 mg/mouse. Particulate coke oven, coal soot diesel exhaust selected as model mixtures based on short-term mutagenicity assays, animal bioassays carcinogenicity or epidemiological studies, where increased...
We demonstrate functionalized spiroligomers that mimic the HDM2-bound conformation of p53 activation domain. Spiroligomers are stereochemically defined, functionalized, spirocyclic monomers coupled through pairs amide bonds to create spiro-ladder oligomers [1]. Two series were synthesized, one structural analogs and stereochemical analogs, from which we identified compound 1, binds HDM2 with a Kd value 400 nM. The spiroligomer 1 penetrates human liver cancer cells passive diffusion in...
Mutational incidence and spectra for genes examined in both human mouse lung liver tumors were analyzed using the National Institute of Environmental Health Sciences (NIEHS) Genetic Alterations Cancer (GAC) knowledge system. GAC is a publicly available, web-based system evaluating data obtained from peer-reviewed studies genetic changes associated with exposure to chemical, physical, or biological agents, as well spontaneous tumors. In mice, mutations Kras2 Hras-1 most common events reported...