- Genomics and Phylogenetic Studies
- Bacteriophages and microbial interactions
- Epigenetics and DNA Methylation
- Microbial Metabolic Engineering and Bioproduction
- Bacterial Genetics and Biotechnology
- Machine Learning in Bioinformatics
- RNA modifications and cancer
- Enzyme Catalysis and Immobilization
- Mycobacterium research and diagnosis
- Genomics and Chromatin Dynamics
- RNA and protein synthesis mechanisms
- Neurogenesis and neuroplasticity mechanisms
- Algal biology and biofuel production
- MicroRNA in disease regulation
Instituto Cajal
2023-2025
Consejo Superior de Investigaciones Científicas
2019-2025
Centro de Biología Molecular Severo Ochoa
2019-2021
Universidad Autónoma de Madrid
2019-2021
University of Bergen
2019
<title>Abstract</title> Long-term memory (LTM) requires transcription and translation of new proteins, but short-term does not. Several signaling pathways factors involved in LTM-related have been identified, yet the transcriptional response to formation retrieval remains poorly understood. Here, we performed a transcriptome time course during LTM Drosophila melanogaster exposed courtship conditioning. We identified mushroom body-specific trace that becomes activated consolidation. For...
NGS long-reads sequencing technologies (or third generation) such as Pacific BioSciences (PacBio) have revolutionized the field over last decade improving multiple genomic applications like de novo genome assemblies. However, their error rate, mostly involving insertions and deletions (indels), is currently an important concern that requires special attention to be solved. Multiple algorithms are available fix these errors using short reads (such Illumina), although they require long...
A high level of transposon-mediated genome rearrangement is a common trait among microorganisms isolated from thermal environments, probably contributing to the extraordinary genomic plasticity and horizontal gene transfer (HGT) observed in these habitats. In this work, active inactive insertion sequences (ISs) spanning sequenced members genus Thermus were characterized, with special emphasis on three T. thermophilus strains: HB27, HB8, NAR1. large number full ISs fragments derived different...
Mycolicibacterium hassiacum is the most thermophilic of all mycobacteria. A partial sequence based on Illumina technology around 5 Mbp was published in 2012.
Summary Lifestyle induces long lasting effects on brain and cognition, with some interventions like stress including transgenerational inheritance mediated by epigenetic mechanisms. Physical exercise is one lifestyle intervention driving robust improvements of intergenerational transmission to the litter. However, little known about whether are transgenerationally transmitted. Here we analyzed adult hippocampal neurogenesis (AHN) behavioral phenotype sedentary male mice F2 generation...