- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Pharmaceutical studies and practices
- Biological Activity of Diterpenoids and Biflavonoids
- Biochemical and biochemical processes
- Natural product bioactivities and synthesis
- Phytochemistry and Bioactive Compounds
- Wound Healing and Treatments
- Flavonoids in Medical Research
- Fungal Biology and Applications
- Bioactive natural compounds
- Morinda citrifolia extract uses
- Chromatography in Natural Products
- Biochemical Analysis and Sensing Techniques
- Bioactive Compounds and Antitumor Agents
- Skin Protection and Aging
- Pharmacological Effects and Toxicity Studies
- melanin and skin pigmentation
- Natural Antidiabetic Agents Studies
Medical University of Białystok
2019-2022
University of Zagreb
2022
Phenolic compounds are secondary metabolites that found ubiquitously in plants, fruits, and vegetables. Many studies have shown regular consumption of these could a positive effect on our health. The aim this study was to compare the phytochemical contents water extracts from three different plants used as folk remedies Turkey: Aesculus hippocastanum, Olea europaea, Hypericum perforatum. A liquid chromatography-electrospray tandem mass spectrometry (LC-ESI-MS/MS) analysis performed explore...
The effects of different extracts obtained from Jasione montana L. (JM1–JM6) and their main metabolites on biological processes during wound healing were evaluated. effect closure in the scratch test was established, collagen type I synthesis anti-inflammatory assessed by flow cytometry a human dermal fibroblast model (PCS-201-012). Additionally, antioxidant activity (DPPH FRAP) degree inhibition elastase participating proliferation skin fibroblasts determined an vitro model. fractions...
Jasione montana is a plant from the family Campanulaceae rich in phenols with health-beneficial properties such as luteolin (LUT) derivatives. In this work, glycerol-based ultrasound-assisted extraction method was developed and optimized for total phenol (TP) LUT content, well antiradical activity (RSA). The best conditions (glycerol temperature, material weight, ultrasonication power) preparation of J. extracts richest TP (OPT-TP), (OPT-LUT), having RSA (OPT-RSA) were determined....
Jasione montana L. (Campanulaceae) is used in traditional Belarusian herbal medicine for sleep disorders children, but the chemical composition and biological activity have not been investigated. In this study, activities of J. extracts, their fractions main compounds were evaluated amelanotic melanoma C32 (CRL-1585) cells normal fibroblasts (PCS-201-012). The extracts analyzed using liquid chromatography-photodiode array detection-electrospray ionization-mass spectrometry...
Potentilla L. species have a long history of use in folk medicine for the management various human ailments. Despite tremendous number studies describing phytochemical and pharmacological profile species, there is paucity scientific data regarding biological activity norvegica. Thus, present study endeavored to assess total phenolic content (TPC), flavonoid (TFC), secondary metabolite composition this plant using LC-ESI-MS-TOF analysis determined potential P. norvegica extracts fractions....
Jasione montana L. (Campanulaceae) is a common biennial plant, with ethnopharmacological report indicates its use in sleep disorders children [1]. Because our previous study showed significant cytotoxic activity of the Et2O fraction (JM4), we decided to evaluate on human melanoma cells (CRL-1585) apoptosis induction ability JM4 (25-100 μg/mL) and main compound 22 (25 assessed as luteolin based LC-MS phytochemical profile. The characterization apoptotic pathways through caspase activation...