- Gut microbiota and health
- Monoclonal and Polyclonal Antibodies Research
- Click Chemistry and Applications
- Ovarian cancer diagnosis and treatment
- Cancer-related molecular mechanisms research
- Banana Cultivation and Research
- Endometrial and Cervical Cancer Treatments
- Cancer Genomics and Diagnostics
- Diet and metabolism studies
- ATP Synthase and ATPases Research
- RNA and protein synthesis mechanisms
- Advanced Breast Cancer Therapies
- thermodynamics and calorimetric analyses
- Colorectal Cancer Treatments and Studies
- Chemical Synthesis and Analysis
- Colorectal Cancer Surgical Treatments
- Statistical Methods in Clinical Trials
- Cancer Research and Treatments
- Protein Degradation and Inhibitors
- Legume Nitrogen Fixing Symbiosis
- 3D Printing in Biomedical Research
- Prostate Cancer Treatment and Research
- Gastric Cancer Management and Outcomes
- Sex and Gender in Healthcare
- Chromosomal and Genetic Variations
South African Medical Research Council
2024-2025
University of Pretoria
2024-2025
University of Zululand
2019-2022
Vaal University of Technology
2017
Protein–protein interactions (PPI) are vital in modulating biochemical pathways many biological processes. Inhibiting PPI is a tremendously important diagnostic and therapeutic strategy averting pathophysiological cues disease progression. Targeting as smart drug discovery tool has been largely overlooked over the years due to their highly dynamic expansive interfacial areas. However recent years, researchers have developed new technologies that potential move this approach up technology...
Bananas (Musa spp. L.) are grouped on the basis of their genomic origins in relation to Musa acuminata (A genome) and M. balbisiana (B genome). The two ancestral wild seeded diploid species evolved vastly different geographical areas contributed several agronomic traits towards present genetic composition cultivated bananas. Most bananas triploid (AAA, AAB ABB), some (AA, BB AB) a few tetraploids (AAAA, AAAB, AABB ABBB). Limitations correct identification A B genomes have generated need for...
Endometrial cancer (EC), a prevalent gynecological malignancy, presents significant challenges due to its genetic complexity and heterogeneity. The genomic landscape of EC is underpinned by alterations, such as mutations in PTEN, PIK3CA, ARID1A, chromosomal abnormalities. identification molecular subtypes—POLE-ultramutated, microsatellite instability (MSI), copy-number low, high—illustrates the diverse profiles within underscores need for subtype-specific therapeutic...
Core-splicing proteins such as small nuclear ribonucleoprotein polypeptide G (SNRPG) and retinoblastoma-binding protein 6 (RBBP6) have been in the spotlight for years because of their regulatory functions mRNA processing active engagement carcinogenesis tumour growth. Varied forms cancer shown to exhibit different amounts expression two proteins. RBPP6 has linked liver, lung, breast, colon, cervical carcinomas, while SNRGP found malignancies prostate, colon. Suggestive evidence postulated...