Palladium-catalyzed oxidative carbonylation of N-sulfonyl-2-aminobiaryls through C–H bond activation and C–C, C–N formation under TFA-free milder conditions has been developed. The reaction tolerates a variety substrates provides biologically important phenanthridinone derivatives in yields up to 94%.

A metal-free one-pot strategy has been developed for the first time to synthesize pharmaceutically important α-amino ketones from readily available benzylic secondary alcohols and amines using N-bromosuccinimide. This new reaction proceeds via three consecutive steps involving oxidation of alcohols, α-bromination ketones, nucleophilic substitution α-bromo give ketones. Importantly, this novel greener avoids direct usage toxic corrosive bromine. methodology employed efficiently amfepramone...

Abstract A facile approach of chemical bath deposition was proposed to fabricate direct synthesis silver sulphide (Ag 2 S) on nickel (Ni) mesh without involvement for binders supercapacitor electrodes. The phase purity, structure, composition, morphology, microstructure the as-fabricated Ag S electrode validated from its corresponding comprehensive characterization tools. electrochemical characteristics electrodes were evaluated by recording measurements such as cyclic voltammetry and...

A novel and metal-free I₂-mediated intramolecular C2 amidation of indoles under mild reaction conditions is developed for synthesis indole fused tetracycles.

A novel molecular I2-catalyzed synthesis of isatins through C(sp3)–H oxidation and intramolecular C–N bond formation 2′-aminoacetophenones with excellent yields up to 97% under transition metal, base, additive, peroxide ligand free conditions is described. The present protocol suitable for gram scale retained its high yield. Further, the synthetic utility this reaction towards bioactive 3-hydroxy-2-oxindoles oxindoles demonstrated.

Abstract An iodine/DMSO‐promoted approach has been developed for the synthesis of indoloquinolines via a sequential sp 3 C−H oxidation/intramolecular cyclization using 2‐(1 H ‐indol‐2‐yl)anilines and aryl methyl ketones. A wide range ketones, including drugs complex bioactive molecule‐derived substrates were compatible in present reaction with yields 30–96%. This protocol proceeds through oxidation ketones to phenylglyoxals, subsequent imine formation, furnish indoloquinolines. Further, is...

We report CBr4 catalyzed Michael addition of indole to α,β‐unsaturated ketones for the synthesis β‐indolylketones through halogen bonding catalysis. This reaction is compatible with a diverse range chalcones, including drug‐derived chalcones containing sensitive functional groups such as amides, yielding products in good yields. Additionally, 3‐indolyl furanoid motifs have been synthesized followed by Paal‐Knorr cyclization utilizing various unsymmetrical 1,4‐enediones one‐pot process

Palladium-catalyzed heteroannulation of N-substituted benzamides with [60]fullerene, which proceeds through direct sp2 C−H bond activation to form 7-membered ring pallada-intermediate C60, led formation [60]fulleroisoquinolinones in moderate good yields (8−64% based on recovered C60). A plausible reaction pathway is proposed.

An efficient, transition-metal-free protocol employing I2/Cs2CO3 for the synthesis of thiosulfonate containing 2-iminoindolin-3-ones motifs has been developed from C-3 phenylthio indoles. The reaction proceeded through intramolecular cyclization involving C–N bond formation, leading to formation indole-fused benzothiazines as a key intermediate. Remarkably, Cs2CO3 played crucial role in an oxygen source, enabling oxidative rearrangement with [1,4]-sulfonyl migration furnish final products...

Abstract An extraordinarily efficient hybrid acids‐assisted, palladium‐catalyzed and chelating‐group‐assisted CH bond activation of N ‐sulfonyl‐2‐aminobiaryls their annulations with [60]fullerene via sequential CC CN formation at room temperature to afford [60]fulleroazepines is demonstrated. The highly regioselective tolerant both electron‐withdrawing electron‐donating groups on the aryl moiety reaction gives monofunctionalized fullerenes in good yields (up 54% isolated yield 92% based...

Conjugated aromatic units of choice can be fused to corannulene in an efficient manner through a photo-induced oxidative cyclization process.

Abstract Rieche formylation of corannulene is shown to afford corannulenecarbaldehyde on a multi‐gram scale, in single step, with an isolated yield 95 %, and without the need chromatographic purification. This compound allowed facile access wide range structures. The developed synthetic routes are expected facilitate utility motif – known for its unique structural electronic properties arena macromolecular materials chemistry.

Abstract Visible‐light‐induced mild, transition metal, base, and photocatalyst‐free green protocol has been developed for the synthesis of tryptanthrin its derivatives. The present reaction is compatible with a wide range substrates good to high yields. Further, novel synthetic transformation derivatives achieved by decarboxylative addition cyanoacetic acid first time. This proceeds visible‐light‐induced single electron transfer between substrate oxygen, followed intramolecular cyclization...

A novel transition metal-free strategy for the synthesis of benzene-fused β-carboline scaffolds has been developed. This protocol offers a rapid and direct pathway to access benzene fused from 2-(1H-indol-3-ylsulfanyl)-phenylamines aryl methyl ketones using an efficient catalytic system I2/DMSO. The present mild proceeds through sequential reactions Kornblum oxidation, Pictet-Spengler cyclization, desulfurization afford desired products in excellent yields up 99%. Moreover, this method wide...

Abstract Organophosphanes promote the [3+2] cycloaddition reactions of dialkyl ( E )‐hex‐2‐en‐4‐ynedioates and [60]fullerene, giving a series cyclopenteno‐fullerenes 3a – k bearing phosphorus ylides. This reaction is initiated by attack nucleophilic phosphanes at α(δ′)‐C atom )‐hex‐2‐en‐4‐ynedioate, which generates 1,3‐dipolar species. These 1,3‐dipoles then react with C 60 followed intramolecular cyclization to give in moderate‐to‐good yields. In cyclic voltmmetry study, these novel...

Transition-metal-free synthesis of chalcogenated furans through the sequential thiol-Michael/Paal–Knorr reaction 1,4-enediones in presence a catalytic amount <italic>p</italic>-toluene sulfonic acid has been developed.

Corannulenecarbaldehyde and corannulenylmethyl triphenylphosphonium bromide are combined through the Wittig olefination reaction to furnish dicorannulenylethene with 70% yield. A subsequent oxidative photocyclization leads annulation of corannulene nuclei produce a C42H18 nanographene structure in 59% Interestingly, only trans isomer forms cocrystals fullerene C60 concave–convex convex–convex π–π stacking interactions. The Mallory could be extended phenanthrene-based diarylethene precursor...

Implementation of non‐planar aromatic motifs in the molecular design π‐conjugated materials represents a paradigm shift that is interesting from fundamental research viewpoint but remains largely underdeveloped. To further facilitate this cause, we report on synthesis and properties two large polycyclic compounds (38 carbon atoms). In one compound planar π‐system pyrene linked to bowl‐shaped hydrocarbon corannulene through C=C bond, which referred as “corannulene–vinylpyrene”. Photochemical...

An I

Abstract A system based on late transition‐metal halides, phosphanes, water, and reducing agents in 1,2‐dichlorobenzene can efficiently catalyze the intermolecular reductive coupling of [60]fullerene with N ‐sulfonylaldimines to afford novel 1,2‐hydrobenzylated derivatives. We found that both group VII B metals (cobalt, rhodium, iridium) VIII (nickel, palladium, platinum) perform this reaction. control experiment absence aldimines produced C 60 H 2 , which showed reaction might proceed via a...

A three-component strategy for the synthesis of 4-thioarylpyrroles from 1,4-enediones, thiols, and ammonium formate in one-pot has been developed. The reaction proceeds through sequential thiol-Michael/Paal–Knorr 1,4-enediones with formation one new C–S two C–N bonds. operationally simple protocol provides direct access to highly functionalized free-NH good excellent yields. synthetic application resulting was demonstrated by oxidation sulfur atom corresponding sulfoxide sulfone.

In this work, we describe the synthesis of a molecule in which fullerene C₆₀ is covalently attached to bowl-shaped polycyclic aromatic hydrocarbon, corannulene. The developed synthetic route comprised four linear steps with isolated yields ranging from 41–91%. first three relate preparation hydrazone derivative corannulene carrying butyric acid methyl ester group. This key compound generates reactive diazo moiety under base-induced decomposition process. generated diazoalkane then...