A5036049635- Radiomics and Machine Learning in Medical Imaging
- Retinal Diseases and Treatments
- Advanced Glycation End Products research
- AI in cancer detection
- Natural Antidiabetic Agents Studies
- Cancer-related Molecular Pathways
- Ubiquitin and proteasome pathways
- Bladder and Urothelial Cancer Treatments
- Hedgehog Signaling Pathway Studies
- Adrenal and Paraganglionic Tumors
- Hormonal Regulation and Hypertension
- Colorectal Cancer Screening and Detection
- Prostate Cancer Diagnosis and Treatment
- Cutaneous Melanoma Detection and Management
- Mathematical Biology Tumor Growth
- Medical Imaging and Analysis
- Urinary and Genital Oncology Studies
- Nonmelanoma Skin Cancer Studies
- Cardiac tumors and thrombi
- Digital Imaging for Blood Diseases
- Medical Imaging Techniques and Applications
- Thyroid Cancer Diagnosis and Treatment
- Cancer and Skin Lesions
- Connexins and lens biology
- Cancer Diagnosis and Treatment
Iuliu Hațieganu University of Medicine and Pharmacy
2022-2025
Establishing basal cell carcinoma (BCC) subtype is sometimes challenging for pathologists. Deep-learning (DL) algorithms are an emerging approach in image classification due to their performance, accompanied by a new concept - transfer learning, which implies replacing the final layers of trained network and retraining it task, while keeping weights from imported layers. A DL convolution-based software, capable classifying 10 subtypes BCC, was designed. Transfer learning three...
Background: Prostate cancer (PCa) is the most frequent neoplasia in male population. According to International Society of Urological Pathology (ISUP), PCa can be divided into two major groups, based on their prognosis and treatment options. Multiparametric magnetic resonance imaging (mpMRI) holds a central role assessment; however, it does not have one-to-one correspondence with histopathological grading tumors. Recently, artificial intelligence (AI)-based algorithms textural analysis,...
Diabetic retinopathy (DR) and cataracts (CA) have an early onset in diabetes mellitus (DM) due to the redox imbalance inflammation triggered by hyperglycaemia. Plant-based therapies are characterised low tissue bioavailability. The study aimed investigate effect of gold nanoparticles phytoreduced with Rutin (AuNPsR), as a possible solution. Insulin, Rutin, AuNPsR were administered early, six-week rat model DR CA. Oxidative stress (MDA, CAT, SOD) was assessed serum eye homogenates,...
Two deep-learning algorithms designed to classify images according the Gleason grading system that used transfer learning from two well-known general-purpose image classification networks (AlexNet and GoogleNet) were trained on Hematoxylin-Eosin histopathology stained microscopy with prostate cancer.The dataset consisted of 439 asymmetrically distributed in four groups.Mean standard deviation accuracy for AlexNet derivate network was 61.17±7 GoogleNet 60.9±7.4.The similar results obtained by...
Basal cell carcinoma (BCC) is the most frequent cancer of skin and comprises low-risk high-risk subtypes. We selected a subtype, namely, nodular (N), micronodular (MN), with aim to identify differences between them using classical morphometric approach through gray-level co-occurrence matrix histogram analysis, as well an based on deep learning semantic segmentation. From whole-slide images, pathologists 216 N 201 MN BCC images. The two groups were then manually segmented compared four...
Diabetic retinopathy (DR) and cataracts (CA) have an early onset in diabetes mellitus (DM) due to the redox imbalance inflammation triggered by hyperglycemia. Plant-based therapies are characterized low bioavailability ocular tissues. The study aimed investigate effect of gold nanoparticles phytoreduced with Rutin (AuNPsR), as a possible solution. Insulin, Rutin, AuNPsR, were administered early, six-week rat model DR CA. Oxidative stress (MDA, CAT, SOD) was assessed serum eye homogenates,...
In a family with Familial Non-Medullary Thyroid Carcinoma (FNMTC), our investigation using Whole-Exome Sequencing (WES) uncovered novel germline
Paraganglioma is a rare neuroendocrine tumor derived from chromaffin cells. The overproduction of catecholamines accounts for the presenting symptoms and cardiovascular complications. clinical presentation frequently overlaps with associated cardiac diseases, delaying diagnosis. Multimodality imaging multidisciplinary team are essential correct diagnosis adequate management.A 37-year-old woman personal medical history long-standing arterial hypertension radiofrequency ablation...