A5011726166- Nanoparticles: synthesis and applications
- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Moringa oleifera research and applications
- Antioxidant Activity and Oxidative Stress
- Fermentation and Sensory Analysis
- Natural Antidiabetic Agents Studies
- Botanical Research and Applications
- Medicinal Plants and Neuroprotection
- Phytochemistry and Biological Activities
- Advanced Glycation End Products research
- Atherosclerosis and Cardiovascular Diseases
- Retinal Diseases and Treatments
- Nigella sativa pharmacological applications
- Tea Polyphenols and Effects
- Plant biochemistry and biosynthesis
- Medicinal Plant Research
- Phytochemicals and Medicinal Plants
- Laser-Ablation Synthesis of Nanoparticles
- Advanced Nanomaterials in Catalysis
- Advanced biosensing and bioanalysis techniques
- Selenium in Biological Systems
- Liver Disease Diagnosis and Treatment
- Vitamin C and Antioxidants Research
- Seed and Plant Biochemistry
Babeș-Bolyai University
2015-2024
Spitalul Clinic Județean de Urgență Cluj-Napoca
2015-2023
The present article reports an environmentally benign method for synthesizing silver nanoparticles using the fruit extract of
European cranberrybush (Viburnum opulus L.) fruits are well known for their biological properties, of which some due to the presence anthocyanins in berries. Current literature provides little information concerning these fruits. The stability from Viburnum fruits, aqueous and ethanolic extracts, stored under darkness 7 days at different temperatures (2 °C, 37 °C 75 °C) pH values (pH = 3 7), was studied here. lowest showed by water extract 7, with half-life constant rate 1.98 h 0.3488 h⁻¹,...
Red fruits are considered a major source of antioxidant compounds in the human diet. They usually contain anthocyanins, phenolic pigments that confer them multiple health-promoting properties. The health benefits these bioactive phytocompounds strongly related to their bioavailability, which has been reported be low. aim present study is investigate changes capacity and anthocyanin content Cornelian cherry fruit extract during gastrointestinal digestion. Thus, work was designed using...
The present study reports for the first time efficacy of bioactive compounds from Ligustrum ovalifolium L. fruit extract as reducing and capping agents silver nanoparticles (AgNPs), developing a green, zero energetic, cost effective simple synthesis method AgNPs. obtained were characterized by UV-Vis spectroscopy, transmission electron microscopy (TEM), X-ray diffraction (XRD) Fourier Transform Infrared spectroscopy (FTIR), confirming that crystalline in nature, spherical shape, with an...
Cornelian cherry (Cornus mas L.) fruits are known for their significant amounts of anthocyanins which can be used as natural food colorants. The storage stability from these fruit extracts, at different temperatures (2 °C, 25 °C and 75 °C), pH 3.02, in the presence two most widely employed preserving agents (sodium benzoate potassium sorbate) was investigated. highest exhibited by anthocyanin extract stored 2 without any added preservative, with half-life constant rate values 1443.8 h 0.48 ×...
Cornelian cherry ( Cornus mas L.) fruits are an important source of bioactive compounds, especially phenolics and anthocyanins which exhibit a high antioxidant activity contribute to their numerous health benefits. The aim this study was evaluate the effect storage temperature on stability polyphenolic compounds extracts, stored under darkness at 2 °C, 22 55 °C 75 respectively. For all ana-lysed conditions, first-order reaction kinetics established for degradation process polyphenols. rate...
To investigate the comparative effects of prenatal exposure to silver nanoparticles (AgNPs) functionalized with citrate and polyphenols on spatial cognition also nitro-oxidative stress apoptosis in hippocampus cerebellum offsprings.Pregnant Wistar rats were orally administered substances from day 10 gestation until 21. Six weeks postpartum, six male offsprings each group used for behavioral evaluation determination oxidative apoptosis.Both groups exhibited hyperactivity anxiety especially...
The main purpose of the present paper is to emphasize non-invasive effect some new prepared nanomaterials on skin diseases (psoriasis) together with procedures obtain them. These materials are based gold nanoparticles and natural compounds extracted from native plants Adoxaceae family (European cranberrybush – Viburnum opulus L. European black elderberry Sambucus nigra L.) possess a known anti-inflammatory activity mainly due their high content anthocyanins other polyphenols. were...
Background: Oral cancer is highly aggressive due to difficult diagnosis, therapy resistance and increasing frequency; thus finding prevention therapies very important. Aim: This study evaluates the use of gold silver nanoparticles (NPs), phyto-synthesized with Cornus mas extract against oral dysplastic lesions. Methods: NPs were characterized by UV-Vis, Fourier-transform infrared spectroscopy, transmission electron microscopy, x-ray diffraction laser Doppler microelectrophoresis. Biological...
To assess ultrastructural changes, alterations in matrix metalloproteinase activity and apoptosis induced by silver nanoparticles (AgNPs) the rat testicle.For 45 days, two groups of animals received different doses AgNPs (0.8 1.5 mg/kg b.w.), a control group was given buffer used as vehicle for AgNPs. At 7 15 days post-treatment, transmission electron microscopy, TUNEL assay, evaluation NFkB, pNFkB, p53, Bcl-2 Nrf2 expressions were performed on removed testes.Transmission microscopy revealed...
The research investigated the effect of gold (Au-CM) and silver nanoparticles (Ag-CM) phytoreduced with Cornus mas fruit extract (CM) on a human colorectal adenocarcinoma (DLD-1) cell line. impact viability DLD-1 tumor cells normal was evaluated. Oxidative stress death mechanisms (annexin/propidium iodide analysis, caspase-3 caspase-8 levels, p53, BCL-2, BAX, NFkB expressions) as well proliferation markers (Ki-67, PCNA MAPK) were evaluated in cells. characterized using UV-Vis spectroscopy...
Diabetic retinopathy (DR) and cataracts (CA) have an early onset in diabetes mellitus (DM) due to the redox imbalance inflammation triggered by hyperglycaemia. Plant-based therapies are characterised low tissue bioavailability. The study aimed investigate effect of gold nanoparticles phytoreduced with Rutin (AuNPsR), as a possible solution. Insulin, Rutin, AuNPsR were administered early, six-week rat model DR CA. Oxidative stress (MDA, CAT, SOD) was assessed serum eye homogenates,...
Cornus mas L. extract (CM) presents hypolipidemic, antioxidant and anti-inflammatory activity. Gold nanoparticles (AuNPs) are considered potent delivery systems may be used to release pharmaceutical compounds at the level of injury. In our study, we gold functionalized with bioactive from (AuNPsCM) in an experimental model a high-fat diet (HFD), assessed their effects on aorta wall but also serum, as compared administration. Sprague Dawley female rats were fed for 9 months HFD. During last...
A test of Raman spectroscopy as a technique to diagnose inflammatory conditions and differentiate the effect treatments with silver gold nanoparticles conjugated natural extracts compared microscopy in experimental acute inflammation.
Cornelian cherries are red fruits which can be considered as a valuable dietary source of antioxidant biologically active compounds, especially anthocyanins. The purpose the present study was to investigate anthocyanins degradation process in cherry juice supplemented with different sweeteners. Four formulations were prepared using sugars (sucrose, fructose) or artificial sweeteners (aspartame and acesulfame potassium). obtained juices stored at three distinct temperatures (2 °C, 25 75 °C)...