- Veterinary Oncology Research
- Nanoplatforms for cancer theranostics
- Nanoparticles: synthesis and applications
- Virus-based gene therapy research
- Nanoparticle-Based Drug Delivery
- Gold and Silver Nanoparticles Synthesis and Applications
- Milk Quality and Mastitis in Dairy Cows
- Liver Disease Diagnosis and Treatment
- Drug-Induced Hepatotoxicity and Protection
- Poisoning and overdose treatments
- Salmonella and Campylobacter epidemiology
- Animal Ecology and Behavior Studies
- Antibiotic Resistance in Bacteria
- Animal Nutrition and Physiology
- Sinusitis and nasal conditions
- Microbial infections and disease research
- Coccidia and coccidiosis research
- Escherichia coli research studies
- Bone Tissue Engineering Materials
- Periodontal Regeneration and Treatments
- Infectious Diseases and Mycology
- Spectroscopy Techniques in Biomedical and Chemical Research
- Anesthesia and Neurotoxicity Research
- Listeria monocytogenes in Food Safety
- Identification and Quantification in Food
University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca
2016-2025
University of Agricultural Sciences, Dharwad
2009-2024
University of Minnesota
2018-2022
Iuliu Hațieganu University of Medicine and Pharmacy
2013-2018
Institutul Regional de Gastroenterologie Prof. Dr. Octavian Fodor
2018
University of Minnesota, Duluth
2018
Technical University of Cluj-Napoca
2013
University of Agronomic Sciences and Veterinary Medicine of Bucharest
2010
In this study, the antibacterial activity of cerium oxide nanoparticles on two Gram-negative and three Gram-positive foodborne pathogens was investigated. CeO2 (CeO2 nps) were synthesized by a Wet Chemical Synthesis route, using precipitation method Simultaneous Addition reactants (WCS-SimAdd). The as-obtained precursor powders investigated thermal analysis (TG-DTA), to study their decomposition process understand nps formation. composition, structure, morphology thermally treated sample...
Pancreatic cancer (PC) is one of the most lethal solid tumor in humans, with an overall 5-year survival rate less than 5%.Thermally active carbon nanotubes have already brought to light promising results PC research and treatment.We report here construct a nano-biosystem based on multi-walled polyethylene glycol (PEG) molecules validated through AFM, UV-Vis DLS.We next studied photothermal effect these PEG-ylated (5, 10 50 μg/mL, respectively) pancreatic cells (PANC-1) further analyzed...
The bioactive glasses can lead to the promotion of growth granulation tissue, while gold nanoparticles (AuNPs) induce acceleration wound healing including tissue regeneration, connective formation, and angiogenesis. aim this study was evaluate impact using glass (BG) BG-AuNPs composites on skin in experimental rat models for 14 days. Sol-gel derived BGs mixed with Vaseline at 6, 12 18 wt% were used repair response skin. During process healing, granulomatous reaction observed treated...
Tobacco usage is linked to multiple cancer types and accounts for a quarter of all cancer-related deaths. smoke contains various carcinogenic compounds, including polycyclic aromatic hydrocarbons (PAH), though the mutagenic potential many tobacco-related chemicals remains largely unexplored. In particular, highly tobacco-specific nitrosamines NNN NNK form pre-mutagenic pyridyloxobutyl (POB) DNA adducts. study presented here, we identified genome-scale POB-induced mutational signatures in...
Therapeutic cancer vaccines (or active immunotherapy) aim to guide the patient's personal immune system eradicate cells.An exciting approach has been offered by nanoscale drug delivery systems containing tumor associated antigens (TAAs).Their capacity stimulate suggested during late years.However, role of macrophages as key-elements in antigen-presentation process following TAAs-containing nanosystems is not completely understood.We aimed evaluate effect gold nanoparticles functionalized...
Abstract There are serious systemic infections associated with methicillin-resistant Staphylococcus aureus (MRSA) and several other types of bacteria leading to the deaths millions people globally. This type mortality is generally caused by increasing number antibiotic-resistant organisms, a consequence evolution via natural selection. After synthesis gold nanoparticles (GNPs) wet chemistry, bio-functionalization IgG molecules was performed. Following administration IgG-GNPs MRSA cultures at...
Background: Establishing the diagnosis of COVID-19 and Pneumocystisjirovecii pulmonary coinfection is difficult due to clinical radiological similarities that exist between two disorders. For moment, fungal coinfections are underestimated in patients. Case presentation: We report case a 52-year-old male patient, who presented emergency department for severe dyspnea died 17 h later. The RT-PCR test performed at his admission was negative SARS-CoV-2. Retesting lung fragments collected during...
Rosmarinic acid is a well-known natural antioxidant and anti-inflammatory compound, it one of the polyphenolic compounds found in comfrey plants. Comfrey root also contains allantoin, which helps with new skin regeneration. This study aimed to investigate healing regeneration process wounds Wistar rats using creams based on extract correlate results active extract. The obtained showed that rich bioactive compounds, including salvianolic acid, rosmarinic are known for their great free radical...
Ossifying fibroma (OF) is a rare, benign fibro-osseous neoplasm that primarily originates from membranous bones. While most frequently documented in equines, OF has also been reported other species, including dogs, though it remains uncommon. The condition poses significant diagnostic challenges due to its ambiguous presentation, often requiring differentiation and malignant intraosseous lesions. This case report describes an ossifying localized the zygomatic bone 9-year-old Hungarian...
Food safety, particularly within the meat industry, is a significant concern addressed under One Health concept, emphasizing necessity of enhanced surveillance and hygiene protocols to mitigate contamination risks. This study assessed microbiological risks in Romanian bovine slaughterhouses by analyzing 150 samples from stool carcasses at post-evisceration cooling stages over seven months two abattoirs, using standardized methods PCR quantify aerobic colony counts (ACCs), Enterobacteriaceae,...
A 2-year-3-month-old neutered male domestic shorthair cat was presented for cardiological evaluation at the University of Agricultural Sciences and Veterinary Medicine in Cluj-Napoca, Romania, with a history dyspnea, open-mouth breathing, cyanosis, exercise intolerance. Physical examination identified grade 4/6 systolic murmur, mild no abdominal abnormalities. Echocardiography revealed right ventricular hypertrophy, severe atrial dilation, thickened tricuspid valve, large nonrestrictive...
Abstract: We present a method of enhanced laser thermal ablation HepG2 cells based on simple gold nanoparticle (GNP) carrier system such as serum albumin (Alb), and demonstrate its selective therapeutic efficacy compared with normal hepatocyte cells. or hepatocytes were treated Alb-GNPs at various concentrations incubation times, further irradiated using 2 W, 808 nm laser. Darkfield microscopy immunochemical staining was used to the internalization inside via Gp60 receptors targeting. The...
Introduction: The occurrence of pathogenic strains in poultry meat is growing concern Romania. Another problem found on a global level the continuous increase antimicrobial resistance bacteria isolated from food. This study aimed to evaluate prevalence carcasses obtained Romania 2012–2013 and reveal most prevalent patterns strains. Methodology: A total 144 broiler chicken were evaluated according classical microbiological methods. DNA was extracted bacterial colonies genes identified by PCR....
Abstract: Systemic infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and other bacteria are responsible for millions of deaths worldwide, much this mortality is due to the rise antibiotic-resistant organisms as a result natural selection. Gold nanoparticles synthesized using standard wet chemical procedure were photoexcited an 808 nm 2 W laser diode further administered MRSA bacteria. Flow cytometry, transmission electron microscopy, contrast phase fluorescence...