Răzvan Vlad Opriș

ORCID: 0000-0002-7055-2113
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About
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Research Areas
  • Amoebic Infections and Treatments
  • Phytochemicals and Antioxidant Activities
  • Sinusitis and nasal conditions
  • Parasitic Infections and Diagnostics
  • Nanoparticles: synthesis and applications
  • Natural Antidiabetic Agents Studies
  • Antibiotic Resistance in Bacteria
  • Flavonoids in Medical Research
  • Plant Pathogens and Fungal Diseases
  • Enterobacteriaceae and Cronobacter Research
  • Selenium in Biological Systems
  • Medicinal Plants and Neuroprotection
  • Antifungal resistance and susceptibility
  • Mycotoxins in Agriculture and Food
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Phytoestrogen effects and research
  • Reproductive System and Pregnancy
  • Oral Health Pathology and Treatment
  • Lipoproteins and Cardiovascular Health
  • Antioxidant Activity and Oxidative Stress
  • Olfactory and Sensory Function Studies
  • Atherosclerosis and Cardiovascular Diseases
  • Toxin Mechanisms and Immunotoxins
  • Moringa oleifera research and applications
  • Helicobacter pylori-related gastroenterology studies

Iuliu Hațieganu University of Medicine and Pharmacy
2016-2023

(1) Background: As β-lactamase-producing Enterobacterales are no longer exclusively associated with the health care system, investigating potential risk they pose to integrity of environment and food safety has become utmost importance. This study aimed determine prevalence extended-spectrum β-lactamase (ESBL), AmpC, carbapenemase-producing isolates from retailed raw vegetables if household washing is an effective method lowering bacterial load; (2) Methods: Seasonal (n = 165) were acquired...

10.3390/foods9121726 article EN cc-by Foods 2020-11-24

To assess ultrastructural changes, alterations in matrix metalloproteinase activity and apoptosis induced by silver nanoparticles (AgNPs) the rat testicle.For 45 days, two groups of animals received different doses AgNPs (0.8 1.5 mg/kg b.w.), a control group was given buffer used as vehicle for AgNPs. At 7 15 days post-treatment, transmission electron microscopy, TUNEL assay, evaluation NFkB, pNFkB, p53, Bcl-2 Nrf2 expressions were performed on removed testes.Transmission microscopy revealed...

10.2217/nnm-2018-0193 article EN Nanomedicine 2019-01-18

Abstract Background Giardia duodenalis is one of the most prevalent and highly diverse human parasites, encompassing a complex eight genetically distinct assemblages, each further divided into sub-assemblages. While in recent years, G. genotype distribution patterns humans have been intensely studied, there still very little information available on diversity genotypes sub-assemblages infecting people Romania. In present study, we investigated genetic asymptomatic patients from Methods Over...

10.1186/s13071-020-04248-2 article EN cc-by Parasites & Vectors 2020-07-31

Cornus mas L. extract (CM) presents hypolipidemic, antioxidant and anti-inflammatory activity. Gold nanoparticles (AuNPs) are considered potent delivery systems may be used to release pharmaceutical compounds at the level of injury. In our study, we gold functionalized with bioactive from (AuNPsCM) in an experimental model a high-fat diet (HFD), assessed their effects on aorta wall but also serum, as compared administration. Sprague Dawley female rats were fed for 9 months HFD. During last...

10.3390/antiox11071343 article EN cc-by Antioxidants 2022-07-08

(1) Background: The study aimed to assess neurobehavioral, ultrastructural, and biochemical changes induced by silver nanoparticles synthesized with Cornus mas L. extract (AgNPs-CM) in rat brains. (2) Methods: included 36 male adult rats divided into three groups. Over a period of 45 days, AgNPs-CM (0.8 1.5 mg/kg b.w.) were administered daily gavage two the groups, while control group received vehicle used for AgNP. After treatment, OFT EPM tests conducted order neurobehavioral changes. Six...

10.3390/nano12010058 article EN cc-by Nanomaterials 2021-12-26

Little evidence has been published regarding the antimicrobial resistance patterns of Helicobacter pylori (H. pylori) strains in Northwestern and Central Romania. The aim this study was to determine antibiotic pattern H. isolates from gastric biopsies collected patients living Romania using ETEST® GenoType HelicoDR. Gastric were obtained 148 adult patients, 87 women 61 men, majority (131 patients) Sixty-nine detected by both culture PCR; sixty-three negative techniques; one biopsy positive...

10.3390/antibiotics12121672 article EN cc-by Antibiotics 2023-11-28

This study aimed to investigate the effect of quercetin without intranasal inflammation and oxidative stress in nasal sinus mucosa, but also serum, lungs brain a rat model acute induced by administration lipopolysaccharides (LPS) (from Escherichia coli). Wistar rats were divided into five groups 10 animals each. The control group received an saline solution once/day, for seven consecutive days. Rats 2 3, low-dose (5 μg) high-dose (10 LPS, 4 5, LPS after h, 80 mg/kg quercetin, once/day days...

10.26402/jpp.2020.4.03 article EN Journal of Physiology and Pharmacology 2020-11-15

The relationship between fungal species and their resistance patterns in vineyard soils has important implications for agriculture medicine. This study explored the prevalence of Aspergillus section Fumigati to azole compounds Romanian soils. A total 265 soil samples from various vineyards were screened fungi resistant azoles. isolates exhibited significant itraconazole voriconazole, but no azole-resistant fumigatus strains detected. Six percent positive strains, all which azole-resistant....

10.3390/antibiotics12121695 article EN cc-by Antibiotics 2023-12-03
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