A5090159672- Bacterial Identification and Susceptibility Testing
- Bacterial biofilms and quorum sensing
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Infective Endocarditis Diagnosis and Management
- Clostridium difficile and Clostridium perfringens research
- Microfluidic and Bio-sensing Technologies
- Streptococcal Infections and Treatments
- Fungal Infections and Studies
- Dental Implant Techniques and Outcomes
- Antifungal resistance and susceptibility
- Actinomycetales infections and treatment
- Microscopic Colitis
- Sinusitis and nasal conditions
- Ocular Diseases and Behçet’s Syndrome
- Protist diversity and phylogeny
- Phytochemistry and Biological Activities
- Vasculitis and related conditions
- Veterinary medicine and infectious diseases
- Cerebrospinal fluid and hydrocephalus
- Head and Neck Anomalies
- Parasitic infections in humans and animals
- Microbial Metabolism and Applications
- Escherichia coli research studies
Iuliu Hațieganu University of Medicine and Pharmacy
2021-2025
Spitalul Clinic Județean de Urgență Cluj-Napoca
2021-2024
Taking into account the increasing number of antibiotic-resistant bacteria, actual research focused on plant extracts is vital. The aim our study was to investigate leaf and stem ethanolic Artemisia absinthium L. annua in order explore their antioxidant antibacterial activities. Total phenolic content (TPC) evaluated spectrophotometrically. Antioxidant activity by DPPH ABTS. wormwood assessed minimum inhibitory concentration (MIC) bactericidal (MBC) Escherichia coli, Staphylococcus aureus,...
Sleep deprivation is highly prevalent in the modern world, possibly reaching epidemic proportions. While multiple theories regarding roles of sleep exist (inactivity, energy conservation, restoration, brain plasticity and antioxidant), unknowns still remain proposed antioxidant sleep. The existing experimental evidence often contradicting, with studies pointing both toward against presence oxidative stress after deprivation. main goals this review were to analyze data relationship between...
(1) Background: This paper aims to provide a description of non-faecalis non-faecium enterococci isolated from tertiary care hospital in Romania and briefly review the existing literature regarding involvement Enterococcus raffinosus, durans avium human infections their antimicrobial resistance patterns; (2) Methods: We retrospectively analyzed all Enteroccocus species “Prof. Dr. O. Fodor” Regional Institute Gastroenterology Hepatology Cluj-Napoca during one year focusing on Enterococci. A...
Antibiotic resistance is on the WHO's top 10 list of global public health threats due to its rapid emergence and spread but also because high morbidity mortality associated with it. Amongst main species driving this phenomenon A. baumannii, a member ESKAPE group medical assistance-associated infections causing famous for extensively drug-resistant phenotypes. Our findings note 91.52% frequency carbapenem-resistant baumannii (XDR CRAB) phenotype amongst clinical isolates from multiple...
Background/Objectives: With the increasing use of dental implants in edentulous patients and high prevalence peri-implantitis, understanding its microbial risk factors is crucial. This study investigated Romanian from two private clinics Cluj-Napoca, Romania, diagnosed with focusing on identifying predominant bacterial species at affected sites compared healthy implant sites. Additionally, we examined impact such as smoking, gender, age, prosthetic restoration type disease prevalence....
COVID-19 offers ideal premises for bacteria to develop antimicrobial resistance. In this study, we evaluated the presence of several resistance genes (ARG) in vancomycin-resistant Enterococcus (VRE) isolated from rectal swabs patients at a hospital Cluj-Napoca, Romania. Rectal were cultivated on CHROMID® VRE (bioMérieux, Marcy-l' Étoile, France) and positive isolates identified using MALDI-TOF Mass Spectrometry (Bruker Daltonics, Bremen, Germany) further analyzed PCR technique following...
(1) Background: Based on the uncontrolled use of antibiotics and lack worldwide-accepted healthcare policies, COVID-19 pandemic has provided best premises for emergence life-threatening infections. changes described in intestinal microbiome, showing an increased number Enterococcus bacteria permeability due to viral infection, infections with have taken spotlight setting; (2) Methods: We conducted a brief review order analyze relationship between two pathogens: SARS-CoV-2 virus bacterial...
is a rare species, part of the viridans streptococcus group, found initially in rabbits and pigs, which can be vancomycin-resistant. We present case 65-year-old patient, smoker chronic alcohol consumer with obstructive pulmonary disease (COPD) multiple dental foci who had been diagnosed bacterial endocarditis caused by
Enterococci commonly cause nosocomial bloodstream infections (BSIs), and the global incidence of vancomycin-resistant enterococci (VRE) BSIs is rising. This study aimed to assess risk factors for enterococcal 30-day mortality, stratified by Enterococcus species, vancomycin resistance, treatment appropriateness. We conducted a retrospective cohort (2014–2021) including all hospitalized adult patients with at least one blood culture positive faecalis or faecium. included 584 BSI: 93 were...
(1) Background: The rise in antibiotic resistant bacteria poses a significant threat to public health worldwide, necessitating innovative solutions. This study explores the role of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) context resistance among different species from
Effective treatment of infectious diseases requires prompt and accurate bacterial identification tailored antimicrobial treatments. Traditional culture methods are considered the gold standard, but their effectiveness diminishes for fastidious hard-to-grow microorganisms. In recent years, molecular diagnostic tools such as 16S rRNA gene next-generation sequencing (16S NGS) have gained popularity in field. We analysed data from samples submitted NGS between July 2022 2023 at Department...
An often-overlooked side of the population aging process and steady rise non-communicable diseases reflects emergence novel infectious pathogens on background an altered host immune response. The aim this article was to present first record a ciliate flagellate protozoa recovered from urine elderly patient review existing medical literature involving these parasites. A 70-year-old female admitted for breathing difficulties basis acute exacerbation COPD (Chronic obstructive pulmonary disease)...
Background: Bacterial biofilm formation (BBF) proves itself to be in the spotlight of microbiology research due wide variety infections that it can associated with, involvement food spoilage, industrial biofouling and perhaps sewage treatment. However, BBF remains difficult study lack standardization existing methods expensive equipment needed. We aim describe a new inexpensive easy reproduce protocol for 3D-printed microfluidic device used dynamic manner. Methods: SolidWorks 3D CAD Software...
The SARS-CoV-2 pandemic has proved to be a significant risk addition for invasive infections with Aspergillus. Even though there are plenty of data about the COVID-19-associated pulmonary aspergillosis (CAPA), especially involving Aspergillus fumigatus, recent studies presenting cases CAPA more than one species We report first case patient associating co-infection with, most likely, section Fumigati and Flavi from Romania, we review existing medical literature in order shed light upon mixed...
Although the COVID-19 pandemic has held spotlight over past years, antimicrobial resistance (AMR) phenomenon continues to develop in an alarming manner. The lack of strict antibiotic regulation added overuse antimicrobials fueled AMR pandemic. This paper aims analyze and identify impact on patterns Enterococcus spp. study was designed as a retrospective observational study. infections data were collected from one academic hospital Cluj-Napoca, Romania 18 months. A statistical analysis...
Little evidence has been published regarding the antimicrobial resistance patterns of Helicobacter pylori (H. pylori) strains in Northwestern and Central Romania. The aim this study was to determine antibiotic pattern H. isolates from gastric biopsies collected patients living Romania using ETEST® GenoType HelicoDR. Gastric were obtained 148 adult patients, 87 women 61 men, majority (131 patients) Sixty-nine detected by both culture PCR; sixty-three negative techniques; one biopsy positive...
A realistic modelling of the way biofilms form and evolve in time requests a dynamic approach. In this study, proposed route uses continuous-flow bioreactors under controlled flow rates temperature culture medium containing bacteria or fungi. 3D printed, Polylactic acid (PLA), flow-based with integrated copper electrodes were used to investigate effect dielectrophoresis on formation growth Staphylococcus aureus ATCC 25923, Enterococcus faecalis 29212, Pseudomonas aeruginosa 27853, Klebsiella...
Background: Alternaria alternata is a melanic fungus capable of causing wide variety infections, some which have lethal potential. It ubiquitous and well-known plant pathogen. Cutaneous infections with most often occur in the extremities patients who perform conventional agriculture, thus being exposed to occupational hazards leading disruption skin barrier. Methods: This paper presents first case report from Romania an itraconazole nonresponsive cutaneous alternariosis patient without any...
Understanding the effect of different electric potentials upon preferential formation biofilms inside microfluidic devices could represent a step forward in comprehending mechanisms that govern biofilm and growth. 3D printed were used to investigate influence dielectrophoretic forces on growth Staphylococcus aureus ATCC 25923 biofilms. Bacterial suspensions 2.5 McF pushed through channels while simultaneously applying various potential differences between 10 60 V. The overall field...