- Veterinary Oncology Research
- Animal Disease Management and Epidemiology
- Essential Oils and Antimicrobial Activity
- Vector-Borne Animal Diseases
- Virus-based gene therapy research
- Viral Infections and Vectors
- Liver Disease Diagnosis and Treatment
- Microbial infections and disease research
- Animal Virus Infections Studies
- Phytochemicals and Antioxidant Activities
- melanin and skin pigmentation
- Skin Protection and Aging
- Infectious Diseases and Mycology
- Photodynamic Therapy Research Studies
- Cancer Research and Treatments
- Helicobacter pylori-related gastroenterology studies
- AI in cancer detection
- Probiotics and Fermented Foods
- Parasitic Infections and Diagnostics
- Bird parasitology and diseases
- Angiogenesis and VEGF in Cancer
- Viral gastroenteritis research and epidemiology
- Drug-Induced Hepatotoxicity and Protection
- Nanoparticles: synthesis and applications
- Antifungal resistance and susceptibility
Ross University School of Veterinary Medicine
2015-2024
University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca
2011-2022
Moredun Research Institute
2019
University of Minnesota
2018
University of the West Indies System
2015
University of Agricultural Sciences, Dharwad
2007-2014
Technical University of Cluj-Napoca
2013
University of Agronomic Sciences and Veterinary Medicine of Bucharest
2010
"Ion Ionescu de la Brad" Iasi University of Life Sciences
2010
Counting mitotic figures (MF) in hematoxylin and eosin–stained histologic sections is an integral part of the diagnostic pathologist’s tumor evaluation. The count (MC) used alone or as a grading scheme for assessment prognosis clinical decisions. Determining MCs subjective, somewhat laborious, has interobserver variation. Proposals standardizing this parameter veterinary field are limited to terminology (use term MC) area (MC counted measuring 2.37 mm 2 ). Digital imaging techniques now...
Standardization of tumor assessment lays the foundation for validation grading systems, permits reproducibility oncologic studies among investigators, and increases confidence in significance study results. Currently, there is minimal methodological standardization assessing tumors veterinary medicine, with few attempts to validate published protocols schemes. The current article address these shortcomings by providing standard guidelines parameters evaluating specific types. More detailed...
The main purpose of the present paper is to emphasize non-invasive effect some new prepared nanomaterials on skin diseases (psoriasis) together with procedures obtain them. These materials are based gold nanoparticles and natural compounds extracted from native plants Adoxaceae family (European cranberrybush – Viburnum opulus L. European black elderberry Sambucus nigra L.) possess a known anti-inflammatory activity mainly due their high content anthocyanins other polyphenols. were...
The integration of deep learning-based tools into diagnostic workflows is increasingly prevalent due to their efficiency and reproducibility in various settings. We investigated the utility automated nuclear morphometry for assessing pleomorphism (NP), a criterion malignancy current grading system canine pulmonary carcinoma (cPC), its prognostic implications. developed algorithm evaluating NP (variation size, i.e., anisokaryosis and/or shape) using segmentation model. Its performance was...
The count of mitotic figures (MFs) observed in hematoxylin and eosin (H&E)-stained slides is an important prognostic marker, as it a measure for tumor cell proliferation. However, the identification MFs has known low inter-rater agreement. In computer-aided setting, deep learning algorithms can help to mitigate this, but they require large amounts annotated data training validation. Furthermore, label noise introduced during annotation process may impede algorithms' performance. Unlike H&E,...
Variation in nuclear size and shape is an important criterion of malignancy for many tumor types; however, categorical estimates by pathologists have poor reproducibility. Measurements characteristics can improve reproducibility, but current manual methods are time-consuming. The aim this study was to explore the limitations develop alternative morphometric solutions canine cutaneous mast cell tumors (ccMCTs). We assessed following evaluation accuracy, prognostic utility: (1) anisokaryosis...
A test of Raman spectroscopy as a technique to diagnose inflammatory conditions and differentiate the effect treatments with silver gold nanoparticles conjugated natural extracts compared microscopy in experimental acute inflammation.