A5071441411- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Dermatology and Skin Diseases
- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Occupational exposure and asthma
- Drug-Induced Adverse Reactions
- Adrenal Hormones and Disorders
- Herpesvirus Infections and Treatments
- Antimicrobial agents and applications
- Viral Infections and Immunology Research
- Nail Diseases and Treatments
- Immunotoxicology and immune responses
- Animal Disease Management and Epidemiology
- Acne and Rosacea Treatments and Effects
- Urticaria and Related Conditions
- Skin Protection and Aging
- Agricultural safety and regulations
- Biomedical and Chemical Research
Isala
2022-2023
University Medical Center Groningen
2013-2019
University of Groningen
2013-2019
Effective treatment options for patients with chronic hand eczema (CHE) are scarce. Dupilumab is licensed the of moderate-to-severe atopic dermatitis and has shown promising results in other studies.
Long-term data of ciclosporin A (CsA) treatment in daily practice patients with severe atopic dermatitis (AD) are lacking.To perform a detailed analysis drug survival, which is the length time patient continues to take drug, for CsA long-term cohort AD. The secondary objective was identify determinants survival.Data were extracted from retrospective treated Drug survival analysed using Kaplan-Meier curves. Determinants uni- and multivariate Cox regression analyses backward selection.In...
Allergic contact dermatitis is a well-known cause of hand eczema, although the influence allergens on different clinical types eczema remains still unclear.To identify most common positive tested among patients and to define relation between specific allergies according guidelines Danish Contact Dermatitis Group (DCDG).We included 1571 subjects who were patch from 1 January 2002 31 December 2013. They retrospectively classified DCDG into six types: recurrent vesicular chronic fissured...
Summary Background Acrylates constitute an important cause of occupational contact dermatitis. Isobornyl acrylate sensitization has been reported in only 2 cases. We encountered industrial process operator with dermatitis caused by isobornyl acrylate. Objectives (i) To investigate whether it is relevant to add the (meth)acrylate test series. (ii) report patients allergy at dermatology clinic. Patients/materials/methods Our patch database was screened for positive reactions (meth)acrylates...
Acitretin has been used off-label for years to treat chronic hand eczema, but acitretin is less often prescribed as alitretinoïne was approved. This study evaluates both retinoids in a daily practice cohort of patients with severe eczema terms drug survival and reasons discontinuation. Patients using alitretinoin or between 01-01-1994 01-08-2015 were included this retrospective analyzed by Kaplan-Meier curves. Potential determinants Cox regression analyses. Ninety-five treated 109 acitretin....
Abstract Background Hand eczema is a common condition; it often chronic and can be difficult to treat. Cyclosporine used off‐label treat severe hand eczema; however, the evidence for this treatment scarce. Objective To examine drug survival of cyclosporine in daily practice cohort patients with eczema. Methods This retrospective use study included who were treated between 01‐06‐1999 01‐06‐2014 two Dutch university hospitals. Patient characteristics retrospectively collected from medical...
Alitretinoin is the only registered systemic treatment of severe chronic hand eczema (HE), but it most effective in hyperkeratotic HE.1 It has never been compared head-to-head studies to other immunomodulating drugs, for example, azathioprine, that can be used (off-label) HE. In one daily practice case series, patients showed moderate-to-good improvement their HE after with azathioprine.2 Based on this which patient was included, combined observations clinical practice, azathioprine could...
Summary Background Tea tree oil is used as a natural remedy, but also popular ingredient in household and cosmetic products. Oxidation of tea results degradation products, such ascaridole, which may cause allergic contact dermatitis. Objectives To identify the optimal patch test concentration for to investigate relationship between positive reaction ascaridole oxidized oil. Patients/materials/methods Three hundred nineteen patients with eczema were tested 1%, 2%, 5%, 250 5%. Readings...