A5066139631- Cancer Research and Treatments
- Cancer Immunotherapy and Biomarkers
- Agricultural Economics and Practices
- Plant Stress Responses and Tolerance
- Domain Adaptation and Few-Shot Learning
- Cancer Mechanisms and Therapy
- Genetic and phenotypic traits in livestock
- Weed Control and Herbicide Applications
- Regional Development and Policy
- Machine Learning in Bioinformatics
- Brain Tumor Detection and Classification
- Plant responses to water stress
- Cancer-related gene regulation
- Agronomic Practices and Intercropping Systems
- Child Nutrition and Water Access
- Neural Networks and Applications
- Biochemical and Molecular Research
- Plant Micronutrient Interactions and Effects
- Microbial Metabolites in Food Biotechnology
- Sesame and Sesamin Research
- Agricultural Science and Fertilization
- Seed and Plant Biochemistry
- Aluminum toxicity and tolerance in plants and animals
- Enzyme function and inhibition
- Legal and Policy Issues
Sardarkrushinagar Dantiwada Agricultural University
2011-2024
Glenmark Pharmaceuticals (India)
2021-2024
Shobhit University
2023
Institute of Medical Sciences
2022
Indian Institute of Technology Guwahati
2018-2019
Jubilant Life Sciences (India)
2018
Sarojini Naidu Medical College
2009-2015
Cadila Healthcare (India)
2013
All India Institute of Medical Sciences
1991
National Botanical Research Institute
1987
Sesame (Sesamum indicum) is an important indigenous oilseed crop but its growth and productivity are severely affected by abiotic stresses. Class III peroxidases key stress related enzymes that exclusively occur in plant kingdom, however, their specific involvement sesame remains largely unexplored. The present study aimed to identify the PRX gene family elucidate role conferring drought tolerance contrasting accessions. Through genome-wide analysis of family, 45 non-redundant members...
Hazards of application hydrogen peroxide to semiclosed space are well known. We present a case suspected gas embolism following irrigation the surgical field during posterior fossa surgery in prone position. Severe cardiovascular collapse occurred when wound was irrigated with solution. Generation pressure gradient leads absorption considerable amount oxygen giving rise features venous embolism. Although associated an uneventful recovery, use for securing hemostatis should be avoided.
The present experiment was conducted during October to February of year 2019−20, investigate the effect salinity on morpho-physiological traits and identify genotype have higher salt tolerance among ten genotypes belongs three grain Amaranth species. Plant growth viz., plant height, shoot root dry weight decreases with increase in stress level (EC 5 10 dS m-1) all genotypes, however significant (p<0.01) genotypic difference were GA-5 maintained maximum under salinity. Percent decrease SDW...
The versatility to learn from a handful of samples is the hallmark human intelligence. Few-shot learning an endeavour transcend this capability down machines. Inspired by promise and power probabilistic deep learning, we propose novel variational inference network for few-shot classification (coined as TRIDENT) decouple representation image into semantic label latent variables, simultaneously infer them in intertwined fashion. To induce task-awareness, part mechanics TRIDENT, exploit...
Background: Akt kinase is a serine/threonine that plays an important role in different cellular processes such as cell proliferation, apoptosis, glucose metabolism, transcription, and migration. It has three isoforms (Akt1, 2, 3) have distinct sometimes contrasting functions cancers. However, to date, most of the inhibitors are directed against generally which would not serve purpose due lack isoform selectivity offtarget toxicity. Therefore, present study elementary step towards demarcation...
Primary anal malignant melanoma is an uncommon and aggressive disease. In many cases, the disease undetected or mistaken for a benign polyp haemorrhoids until it reaches advanced stage. Extracutaneous melanomas require special consideration due to their late diagnosis consequently poor prognosis. are considered be biologically more than cutaneous counterparts. Surgical excision remains cornerstone of therapy. This case reported because rarity in canal found 80 year old female who was managed...
Background: Non-communicable disease (NCD) is the leading cause of death, accounting for 70% total death globally, and posing a major public health challenge.In India, nearly 5.8 million people (WHO report, 2015) die from NCDs every year.The basic element NCD prevention identification associated risk factors modification.The objective current study was conducted to assess prevalence among healthcare staff two units Tertiary Cancer Hospital in Varanasi, using WHO STEPS approach.Methods: This...
A field experiment was conducted during kharif 2023 to study the efficacy of pre and early post-emergence herbicides for management weeds in blackgram. The laid out a randomized block design with 12 treatments replicated thrice. weed free treatment recorded significantly higher seed stover yield (1077 2657 kg/ha, respectively). After free, yields (960 2258 respectively) were observed interculturing followed by hand weedings at 20 40 DAS found par application imazethapyr + imazamox @ 50 (25...
Masked Autoencoders (MAEs) are an important divide in self-supervised learning (SSL) due to their independence from augmentation techniques for generating positive (and/or negative) pairs as contrastive frameworks. Their masking and reconstruction strategy also nicely aligns with SSL approaches natural language processing. Most MAEs built upon Transformer-based architectures where visual features not regularized opposed convolutional neural network (CNN) based counterparts, which can...
<h3>Background</h3> Casitas B-lineage lymphoma-b (Cbl-b), a protein of the Cbl family ring finger E3 ligases,<sup>1</sup> regulates innate and adaptive immune activation by mediating ubiquitination degradation various signalling transducers.<sup>2 3</sup> A master regulator downstream TAM receptors (NK-cells)<sup>4</sup> CD28/CTLA4 (T-cells), Cbl-b promotes an immunosuppressive milieu in TME (tumor microenvironment), limiting anti-tumor effector functions T NK cells.<sup>5</sup> Lack CD28...
Abstract Background: Pre-clinical profile of GRC 54276, a clinical candidate with Phase 1/2 trial ongoing, is presented here. 54276 novel small molecule inhibitor Hematopoietic progenitor kinase 1 (HPK1), serine/threonine kinase1,2 that negatively regulates T and B cell receptor signaling3. Inhibition HPK1 an attractive therapeutic strategy for immuno-oncology based treatment solid tumors3. Methods: was designed developed using SAR medicinal chemistry design supported by computational...