- Aquatic Ecosystems and Biodiversity
- Aquaculture Nutrition and Growth
- Mycobacterium research and diagnosis
- Bacterial biofilms and quorum sensing
- Tuberculosis Research and Epidemiology
- Physiological and biochemical adaptations
- Antimicrobial Resistance in Staphylococcus
- Fish Biology and Ecology Studies
- Malaria Research and Control
- Aquatic Ecosystems and Phytoplankton Dynamics
- Essential Oils and Antimicrobial Activity
- Aquaculture disease management and microbiota
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive biology and impacts on aquatic species
- Gut microbiota and health
- Genetic diversity and population structure
- Sperm and Testicular Function
- Diagnosis and treatment of tuberculosis
- Primate Behavior and Ecology
- Animal Behavior and Welfare Studies
- Moringa oleifera research and applications
- Antimicrobial Peptides and Activities
- Cancer Research and Treatments
- Agricultural pest management studies
- Pharmaceutical and Antibiotic Environmental Impacts
Maseno University
2010-2024
Moroccan Agency For Solar Energy (Morocco)
2014
University of Konstanz
2010
Effects of high stocking densities (HSDs) were evaluated for Nile tilapia fish ( Oreochromis niloticus ) under culture to determine its influence on plasma cortisol and whole blood glucose concentration. Plasma levels (ng/ml) assayed by E nzyme- L inked I mmuno s orbent A ssay (ELISA). Whole determined using a hand-held one touch ultraglucose meter (MD-300) test strips. level determinations replicated three times O. reared both low (LSD) HSD. One way Analysis Variance (ANOVA) was performed...
ABSTRACT In combination with antibiotics, quinine is recommended as the second-line treatment for uncomplicated malaria, an alternative first-line severe and of malaria in first trimester pregnancy. Quinine has been shown to have frequent clinical failures, yet mechanisms action resistance not fully elucidated. However, linked polymorphisms multiple genes, including multidrug 1 (Pf mdr1 ), chloroquine transporter crt sodium/hydrogen exchanger gene nhe1 ). Here, we investigated association...
The aim of the present study was to assess effect extrinsic factors on antimicrobial effectiveness essential oils (EOs) against medically important gram positive and negative bacteria. Clove, oregano, bay cinnamon were tested against Salmonella typhimurium, Escherichia coli, Bacillus cereusand Listeria innocua. Agar diffusion test used estimate strength oil. Clove most effective all groups minimum inhibition concentrations (MIC) four ranged from 1.25 3.50% (v/v) as determined by...
Fish farmers have a tendency of employing high stocking density (HSD) as means increasing productivity. However, HSD is chronic stressor that likely to lower profitability fish farming if not implemented properly. induces stress which in turn elevates sequentially the levels plasma cortisol and glucose. The resultant glucose distributed various tissues by transporter protein (GLUTs) restore normalcy. GLUT 1, transmembrane found erythrocytes, responsible for import export red blood cells....
Over 65% of human infections are ascribed to bacterial biofilms that often highly resistant antibiotics and host immunity. Staphylococcus epidermidis is the predominant cause recurrent nosocomial biofilm-related infections. However, susceptibility patterns S. physico-chemical stress induced by commonly recommended disinfectants [(heat, sodium chloride (NaCl), hypochlorite (NaOCl) hydrogen peroxide (H2O2)] in domestic healthcare settings remains largely unknown. Further, molecular mechanisms...
Abstract Staphylococcus epidermidis is the predominant cause of recalcitrant biofilm-associated infections, which are often highly resistant to antibiotics. Thus, use physico-chemical agents for disinfection offers a more effective approach control S. biofilm infections. However, underlying tolerance mechanisms employed by against these disinfectants remain largely unknown. The expression σ B -dependent gene, alkaline shock protein 23 ( asp23 ) and catalase activity planktonic cells exposed...
The novelty and suitability of the mitochondrial gene CO1 in DNA barcoding as a reliable identification tool animal species are undisputed. This is attributed to its standardized sequencing segment cytochrome c oxidase-1 (CO1) which has necessary universality variability making it generally acceptable barcode region. haploid single locus that uniparentally-inherited. Protein-coding regions present high-copy numbers an ideal barcode. oxidase subunit I (COI) robust with suitable threshold for...
Abstract Chironomidae is a group of diptera insects, commonly known as “non-biting midges'' in the adult stage and “bloodworms” larval stage, represent insects that thrive various aquatic environment worldwide. Despite plethora information on many parts world, there paucity data regarding this indicator species polluted Kenyan Nyanza Gulf Lake Victoria molecular identification has not been explored. This study aimed to characterize based mitochondrial DNA barcoding cytochrome oxidase subunit...
The Chironomidae family, known as "non-biting midges" in their adult stage and "bloodworms" larval stage, consists of diverse dipteran insects inhabiting various global aquatic environments. Despite extensive research, data on the polluted Nyanza Gulf Lake Victoria, Kenya, is scarce, molecular identification methods have not been explored. This study aimed to quantify heavy metal concentrations water, sediment, insect samples assess impact Chironomid species identified using mitochondrial...
Background. Tuberculosis (TB) remains a high-burden infectious disease worldwide. Mycobacterium tuberculosis complex (MTBC) is the aetiological agent of TB. Research Gap. The TB burden significantly linked to development drug-resistant strains. Thus, there an urgent need for close surveillance MTBC circulating in given region, such as Western Kenya, treatment Aim. To determine proportion species, strains and genetic diversities circulation HIV/AIDS-prevalent regions, Kenya particular....
Chronic stress poses a significant challenge to aquaculture production, and cortisol glucose have traditionally served as markers. However, recent doubts emerged about the reliability of scale chronic determinant due its involvement in calcium homeostasis. While influences gene expression response cascade, few studies explore impact on metabolic pathways cultured Nile tilapia. This study delves into relationship between signatures tilapia regulation Mitogen Activated Protein Kinase (MAPK)...
<ns3:p>Background Malaria during pregnancy is a serious threat to maternal and child health in malaria-endemic regions. often leads placental malaria, which has severely detrimental effects on fetal outcomes, including growth restriction, preterm delivery, stillbirth. However, the mechanisms by malaria causes adverse outcomes remain poorly understood. Crucially, there are no tools for detecting and/or intervening pregnancy. This mainly because placenta inaccessible research Nonetheless, its...
It is widely accepted that bacterial biofilms are overly resistant to antibiotics, host immunity and disinfectants. Biofilms develop on various food-processing surfaces hence pose major risks in food industries. serve as protective niches for pathogens water thus enhance transmission of borne pathogens. Furthermore, implicated medical implant infections. The serious problems associated with food, biomedical environmental fields have stimulated active research over two decades. Biofilm cells...
Abstract We carried out a postrelease evaluation to determine predictors of habitat use and carrying capacity for the black rhinoceros ( Diceros bicornis michaeli) , which are critical monitoring how Ruma National Park sub‐population may contribute Kenya's meta‐population strategy. determined whether level elevation, rockiness, shade, distance fence, roads, human settlements predict use, differences in diet preference between female male rhinoceros, ecological (CC) park. used standard...
Maize is a vital staple crop in Kenya, serving as primary source of food and feed. Contamination maize (Zea mays) by Aspergillus flavus the subsequent production aflatoxins pose significant threats to safety human health. The risk A. contamination on imported at both gazetted un-gazetted points entry has not been extensively studied. objective this study was examine genotypic, phenotypic, aflatoxigenic traits biovars derived from Gazetted Un-gazetted Points Entries Kenya. Furthermore, sought...
Tuberculosis (TB) remains a burden in many countries, including Kenya, especially, Western Kenya. Mycobacterium tuberculosis complex (MTBC) is the etiological agent of tuberculosis. TB majorly linked to development drug resistant strains. For treatment TB, there need for close surveillance MTBC circulating given region. Hence, this study aimed determine proportion species, strains and genetic diversity circulation an HIV prevalent region, western Clinical isolates archived between 2013 2014...
Background. Tuberculosis (TB) remains a high burden infectious disease worldwide. Mycobacterium tuberculosiscomplex (MTBC) is the etiological agent of TB. Research Gap. TB majorly linked to development drug resistant strains. Thus, there urgent need for close surveillance MTBC circulating in given region like Western Kenya treatment Aim. To determine proportion species, strains and genetic diversities circulation an HIV/AIDS prevalent regions especially Kenya. The clinical isolates were...